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    ‘Americans should be alarmed’: Experts say loss of expertise at CDC will harm US health

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    After high-profile departures and sweeping layoffs, the US Centers for Disease Control and Prevention (CDC) faces an unprecedented loss of expertise and a simultaneous erosion of trust as top health leaders undermine vaccines and other vital health tools.“Americans should be alarmed,” said Nirav Shah, former principal deputy director at CDC and now a visiting professor at Colby College. “All of these moves leave us less safe, and it comes at a time of rising public health threats.”Project 2025, the conservative blueprint for the second Trump administration, vowed to strip the CDC of its ability to issue guidance on vaccines and to end required testing for new pathogens.The changes to US health will be felt for decades, and the cutbacks and changes will erode the public’s already wavering trust in health officials, experts say.“Losing top, experienced experts managing crucial units in the CDC is going to put all of us at risk,” said Dorit Reiss, professor of law at UC Hastings College of Law.The departure of four senior officials – Debra Houry, Demetre Daskalakis, Daniel Jernigan and Jennifer Layden – dealt “a big blow to our nation’s health preparedness”, Shah said.They joined thousands of health agency employees who have been laid off or resigned, with entire departments gutted, since Donald Trump was re-elected.“Next time there’s a problem, we will not have qualified leadership for our response,” Reiss said.The loss of “experienced, world-class” experts at the CDC is “directly related to the failed leadership of extremists” in charge of the Department of Health and Human Services (HHS), said Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota.The losses may continue under budget cuts, with proposed reductions of $5bn – a 42% decrease from 2024.Two of the recently ousted officials will testify before Congress on Wednesday. Susan Monarez, the most recent CDC director, who was fired after 28 days, criticized the administration’s “reckless” approach to science, including a request to “rubber-stamp” recommendations from the CDC’s independent advisers.The advisory committee on immunization practices (ACIP) plans to meet on Thursday and Friday. Advisers have indicated the committee will re-examine recommendations on routine childhood vaccinations such as those against hepatitis B and HPV (human papillomavirus).The Make Our Children Healthy Again Strategy released on Tuesday “reaffirms that Kennedy is gunning for childhood vaccines”, Reiss said.Emily Hilliard, an HHS spokesperson, said: “Secretary Kennedy has been clear: the CDC has been broken for a long time. Restoring it as the world’s most trusted guardian of public health will take sustained reform and more personnel changes.”When asked about Kennedy’s stance on childhood vaccines, Hilliard said that HHS is “reaffirming the importance of the doctor-patient relationship so people can make informed decisions about their health”, emphasizing the roles of “clear, honest information and personal choice”.Kennedy has also limited access to the Covid vaccines, restricting them only to people “at higher risk”, while also saying “anyone can get the booster”.“Kennedy’s claim that anyone can get them is deeply insincere,” Reiss said. He already removed, for example, the recommendation for pregnant people, making it harder for them to access the vaccine.skip past newsletter promotionafter newsletter promotion“While it’s legal to give vaccines off-label, not all doctors and pharmacists will, and depending what ACIP does, not all insurers will cover them”, including Medicaid, which is bound by ACIP recommendations, she said.Kennedy has repeatedly undermined the CDC and vaccines, calling the agency a “cesspool of corruption” and the Covid vaccine, for instance, the “deadliest vaccine ever made”. During the worst measles outbreak in decades, Kennedy framed vaccination as a personal choice. He has also cut millions of dollars for research on mRNA vaccines.Earlier this month, Trump defended the Covid and polio vaccines. But the president has given Kennedy sweeping control over the nation’s health and nutrition agenda.“In an era of rising threats to public health – whether it’s measles, whether it’s an Ebola outbreak, or whether it’s the continuing concern and threat from H5 [bird flu] – none of these things makes America healthy again,” Shah said.The acting director of the CDC, Jim O’Neill, has a background in biotechnology investing but he does not appear to have training in medicine or public health.“Based on what I understand, he does not have the requisite background to even be serving as acting director,” said Shah, who was acting director of the CDC while the Trump administration entered office.“Americans need to ask themselves: ‘Are we safe right now?’” Shah said. “‘Is there somebody who knows at the higher levels what should be done in the face of an emerging Ebola outbreak? Are they doing it? How do we know that?’”The news that top experts at the CDC haven’t briefed Kennedy is “alarming”, Shah said. ”If America’s top generals were planning a war and sketching out battlefield plans but had not talked to any of their lieutenants and colonels in the field, we would say that’s not leadership.”So far, many Americans have not yet felt the shock waves of Kennedy’s changes to public health, Shah said.For most people, “you don’t actually see the consequences of it until there’s an emergency”, Shah said. “And it’s way too late at that point.” More

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      Guided by angels, pursued by chemtrails: the weird world of Florida health chief’s influential wife

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      The wife of Florida surgeon general Dr Joseph Ladapo, a leading vaccine skeptic, believes that angels have spoken to her and that “dark forces” are targeting her family with chemtrails, and has claimed her husband won’t work with anyone she hasn’t vetted.In published works and interviews reviewed by the Guardian, Brianna Ladapo – who edited her husband’s USA Today op-ed from March 2020 against Covid-19 shutdowns and appears alongside him at conferences – claims to have regularly received visions that come true and believes her life has been saved “multiple times” by angels.Joseph Ladapo, a longtime vaccine skeptic who was handpicked by Florida’s governor, Ron DeSantis, has faced accusations by public health advocates of peddling “scientific nonsense”. Ladapo has defended his stances on vaccines and Covid guidance, stating in 2023 in response to allegations he falsified a Covid report: “Between my scientific experience and training, and the fact that I am only comfortable saying the truth and speaking the truth, I felt completely fine with that announcement.”He recently ended vaccine mandates for children in Florida against preventable diseases, including measles, mumps, chickenpox, polio and hepatitis, comparing mandates to “slavery” and claimed the move would receive the blessing “of God”. Florida is the first state in the US to do so.The Guardian made several attempts to reach Brianna Ladapo and Joseph Ladapo by email. They did not respond to multiple requests for comment. The Florida department of health and DeSantis also did not respond to multiple requests for comment.In a Substack post on 5 September, Brianna Ladapo defended her husband’s decision to end vaccine mandates and claimed there are “dubious origins, nonexistent safety profiles, and dirty money trails surrounding vaccines”.She wrote in the post: “You believe in vaccines because you’ve been told to by a corrupt medical establishment that has a vested interest in keeping you subservient and stupid.”In a July 2025 podcast, Brianna Ladapo stated: “I often think if I hadn’t had to learn to trust my own gut and learn how to think and stand on my own two feet at such a young age, when Covid had come through, apparently swept away everyone’s brains, I might have been swept away right along with it if I didn’t already know how to listen to that truth that I believe is inside every single one of us.”She added in the podcast that “even to the lead-up, I was having visions, I was having dreams”, about the pandemic, before it began in early 2020. “Immediately, ridiculous inconsistencies started to show themselves.”She also appeared in an interview with the prominent anti-vaccine group Children’s Health Defense in January 2025, in which she said: “If we all listen to our intuition, we listen to that voice, we would not fall for propaganda. Like, what’s happened with Covid. People did truly insane things to keep from catching a virus that over, well over 99% of people survived without intervention, right? That’s textbook insanity.”Joseph Ladapo has appeared with his wife on stage at conferences on health and parenting.In Dr Ladapo’s 2022 memoir, Transcend Fear, he wrote that his wife has “a history of extraordinary experiences that were hard to explain with natural laws”. In March 2020, he wrote an op-ed for USA Today against shutdowns in response to Covid-19, the first of several he wrote about the virus, and noted that it was edited by his wife.Joseph Ladapo wrote in Transcend Fear that when he was recruited for the job of Florida surgeon general by DeSantis, his wife claimed it was the message she was waiting for.In Brianna Ladapo’s 2023 memoir, she claimed “as long as I can remember, I have received communications from beings beyond this realm. Even as a young child, angels regularly spoke to me.”She added that “since I was born, I have also received constant communications in the form of visions” and that “eventually, every single one of them came to pass”.In the book, Brianna Ladapo claims she went on a “pilgrimage” trip to Egypt in graduate school during which she saw the rest of a “recurring vision” from a past life.In a video podcast on Rumble earlier this year, she reiterated these claims about her “gifts”.“I was born a very sensitive child, the kind of kid who would see angels and talk to beings that no one else could necessarily perceive,” she said, claiming her family “perceived what was happening to me as satanic and demonic and evil”.skip past newsletter promotionafter newsletter promotion“I saw a lot of angels, but my angels would talk to me and they saved my life multiple times,” she claimed.Brianna Ladapo also claimed their children together “have all been having experiences like this since they were born” and have “innate divine intelligence”.She claimed one of her children as a baby had “a gift” that was temporarily shared with her.“I started to hear conversations that sounded like they were right next to me. There were no people anywhere near us. And they were clearly from different eras, sometimes different countries, different languages and dialects,” Ladapo said.She said initially in their relationship, her husband was skeptical, but came to believe in her “gifts”.“After a number of years, he came to deeply trust my gift and now he won’t work with anybody I haven’t vetted,” she said. The couple did not respond to requests for comment about Brianna Ladapo’s vetting.Later in the podcast, Ladapo claimed she floated an inch above the ground during a session with a former Navy Seal and self-proclaimed traditional healing guru, whom she said her husband had also seen and had similar experiences with. The healer declined to comment, citing client confidentiality.Ladapo is also a proponent of the chemtrails conspiracy theory about planes mass-dumping chemicals. She claims in the podcast interview that she and her children got sick because of chemtrails, and she used a patch that has been characterized as pseudoscience by medical experts.“As we try to chase down where this is coming from, who is funding the companies who are flying the planes, who are piloting these planes, where are they taking off? We don’t even know where they are, because none of this is on the books.” Ladapo said about chemtrails.She added in the podcast interview about a photo of a Florida sky outside of her home: “This is how the chemtrails have been looking outside our window for the past few weeks. They are, I hate to say it, but that looks like a pentagram and they’ve been plastering it in the sky right outside our house for the last few weeks.”She characterized the perceived chemtrailers as “dark forces” out to get her and her husband.“They’ve been trying to stop us for years,” she claimed. “We are operating at a level of light that puts us essentially out of the grasp of those with a very low vibration, very evil intention.” More

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      RFK Jr does not just reject vaccines. He rejects science and must step down | Bernie Sanders

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      Since taking office, Robert F Kennedy Jr, the secretary of the health and human services department (HHS), has undermined vaccines at every turn. He has dismissed the entire Centers for Disease Control and Prevention (CDC) vaccine advisory panel, narrowed access to life-saving Covid-19 vaccines, filled scientific advisory boards with conspiracy theorists and fired the newly appointed CDC director for refusing to rubber-stamp his actions.But his rejection of vaccines is only part of the problem. Secretary Kennedy is unfit to be our nation’s leading public health official because he rejects the fundamental principles of modern science.For generations, doctors have agreed that germs – like bacteria or viruses – cause infectious diseases.In the 1850s, John Snow, known as the father of epidemiology, traced a cholera outbreak in London to water contaminated with human waste – not the “bad air”, or so-called miasma, that many at that time believed to be the cause.In the 1880s, Louis Pasteur, the French chemist, in a controlled experiment, injected one group of sheep with an anthrax vaccine while another group went without it. Then he injected all of the sheep with anthrax bacteria. The vaccinated sheep survived, the unvaccinated did not.The germ theory led to a revolution in public health and medicine which, over the years, has saved tens of millions of lives.Just a few examples.At a time when many women were dying during childbirth at hospitals, Dr Ignaz Semmelweis found that handwashing by doctors saved lives.Joseph Lister showed that sterilizing medical equipment before surgery prevented needless deaths.Florence Nightingale, considered the mother of modern nursing, substantially improved hygiene at hospitals and made healthcare much safer for patients.Pasteur made the food we eat and the milk we drink safer through a process of heating called pasteurization.And these are just a few examples.Yet, incredibly, in the year 2025, we now have a secretary of HHS who has cast doubt and aspersions on the very concept of the germ theory – the very foundation of modern medicine for over a century.In his book The Real Anthony Fauci, Kennedy absurdly claims that the central tenet behind the germ theory “is simply untrue”. Vaccines are not, Kennedy falsely asserts, responsible for the massive decline in deaths from infectious diseases. Instead, Kennedy falsely proclaims that “science actually gives the honor of having vanquished disease mortalities to sanitation and nutrition”.Yes. No one disputes that proper sanitation, a nutritious diet and exercise can lead to healthier lives. But no credible scientist or doctor believes that alone makes a person immune from polio, measles, mumps, Covid, HIV/Aids and other infectious diseases. Otherwise healthy people can become sick, hospitalized or even die from these and other terrible diseases.Sadly, Kennedy’s dangerous rejection of well-established science is behind his wild conspiracy theories and misinformation campaigns.It’s what led to Kennedy’s false assertion that “there is no vaccine that is safe and effective” despite peer-reviewed scientific studies finding that vaccines have saved more than 150 million lives and reduced infant deaths by 40% in the past 50 years.It’s behind Kennedy’s bogus claim that the polio vaccine “killed many, many, many, many, many more people than polio ever did”, even though the scientific data has shown that the polio vaccine has saved 1.5 million lives and prevented about 20 million people from becoming paralyzed since 1988.It undergirds his history of promoting the ridiculous idea that HIV does not cause Aids, despite rigorous studies finding the exact opposite. This type of outrageous HIV/Aids denialism is widely believed to have caused the deaths of at least 330,000 people in South Africa who did not receive the life-saving medicine they needed.It’s what led him to say that the Covid vaccine was the “deadliest vaccine ever made”, that vaccines cause autism, and that the hepatitis B vaccine doesn’t work and should only be used for “prostitutes” and “promiscuous gay men” – lies that have been thoroughly debunked by scientific data and the medical community.Frighteningly, it’s what caused Kennedy to say: “I see somebody on a hiking trail carrying a little baby and I say to him, ‘Better not get him vaccinated.’ And he heard that from me. If he hears it from 10 other people, maybe he won’t do it.”As a private citizen, Kennedy is entitled to his views, no matter how misguided they may be.If Kennedy would like to swim in water contaminated by raw sewage and fecal matter, as he has done recently in Washington DC’s Rock Creek Park, he is free to do that.But as our nation’s top health official, Secretary Kennedy’s rejection of science and the actions he has taken as a result of his bizarre ideology is endangering the lives of millions of children in the United States and throughout the world.Today, Kennedy is making it harder for people to get vaccines. Tomorrow, what will it be? Will he tell doctors they don’t need to wash their hands before surgery? Will he tell hospitals that they don’t need to sterilize their scalpels and other medical equipment?The American people need a secretary of HHS who will listen to scientists and doctors, and not conspiracy theorists.We need a secretary of HHS who will listen to medical experts who may disagree with him, not fire them summarily.Bottom line: we need an HHS secretary who will not engage in a war on science and the truth itself.Secretary Kennedy must step down.

      Bernie Sanders is a US senator, and ranking member of the health, education, labor and pensions committee. He represents the state of Vermont and is the longest-serving independent in the history of Congress More

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      RFK Jr accused of ‘reckless disregard for science and the truth’ in Senate hearing

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      The US health secretary, Robert F Kennedy Jr, faced the Senate finance committee in a tense and combative hearing on Thursday, during which lawmakers questioned his remarks expressing vaccine skepticism, claims that the scientific community is deeply politicized and the ongoing turmoil plaguing the Centers for Disease Control and Prevention (CDC).In a hearing lasting more than three hours and ostensibly about the Trump administration’s healthcare agenda, Kennedy defended his leadership at the Department of Health and Human Services (HHS), claiming that his time at the agency will be focused on “unbiased, politics-free, transparent, evidence-based science in the public interest”.Senate Democrats on the committee began the hearing calling for Kennedy’s resignation. “Robert Kennedy’s primary interest is taking vaccines away from Americans,” ranking member Ron Wyden, a Democratic senator from Oregon, said in his opening remarks. “People are hurt by his reckless disregard for science and the truth in this effort. I hope the very least, Robert Kennedy has the decency to tell the truth this morning.”Raphael Warnock, also a Democrat, called Kennedy a “hazard to the health of the American people”, repeating calls for him to step down or for Donald Trump to fire him.Last week, Kennedy fired the CDC director, Susan Monarez, less than a month after she was confirmed to her position. She is now mounting a legal case challenging her removal.Shortly after Monarez’s termination, several leading public health officials at the CDC resigned from their positions, citing frustration with Kennedy’s approach to vaccines and his management style.Kennedy said Monarez was “lying” about her claims that she was fired for refusing to sign off on the secretary’s new vaccine policies. Instead, Kennedy said that she was removed after admitting to being untrustworthy.The Democratic senator Elizabeth Warren, of Massachusetts, was unconvinced – citing Kennedy’s prior characterization of the former CDC director as “unimpeachable”.“You had full confidence in her and you had full confidence in her scientific credentials, and in a month she became a liar?” she asked. Thom Tillis, the outgoing Republican senator of North Carolina, asked about the same contradiction in his questioning.Monarez’s lawyers responded in a statement to Kennedy’s comments, calling them “false” and “at times, patently ridiculous”. They added that Monarez would repeat her published claims “under oath”.Kennedy also justified wider firings at the CDC , calling them “absolutely necessary”.“We are the sickest country in the world,” he said. “That’s why we need to fire people at CDC. They did not do their job. This was their job to keep us healthy.”In June, Kennedy fired all 17 members of the CDC’s vaccine advisory committee – a move that defied a promise he made during his confirmation hearing to Republican senator Bill Cassidy, a physician who chairs the Senate health committee. Many of Kennedy’s replacements for the advisory panel have a history of vaccine skepticism.When asked about the changes to the advisory committee, and how that will change vaccine recommendations and scheduling, Kennedy said he didn’t anticipate changes to the MMR (measles, mumps and rubella) vaccine.In an exchange with Kennedy, Cassidy noted the possible conflict of interest with some of the panel’s new members who are involved in ongoing litigation with vaccine manufacturers.Cassidy cast a critical vote to confirm Kennedy earlier this year. He had previously expressed a number of concerns about the health secretary’s historic comments that undermined vaccine efficacy. The senator has since been critical of a number of Kennedy’s policies, including his decision to cut half a billion dollars worth of mRNA vaccine funding – calling the move “unfortunate”.skip past newsletter promotionafter newsletter promotionLast month, the Food and Drug Administration (FDA) approved the new batch of Covid-19 vaccines, but placed restrictions on who would be able to access them. The agency has authorized shots for people 65 and older, who are known to be more at risk from serious illnesses from Covid infections. Younger people will only be eligible if they have an underlying medical condition that makes them vulnerable. Infectious disease experts say that this policy could prove extremely dangerous, particularly for young children.On Tuesday, Kennedy defended HHS’s handling of the measles outbreak that affected several states in an opinion piece. While the secretary branded his agency’s response as effective, public health experts said Kennedy’s own messaging around vaccines was muddied and confusing.Cassidy concluded his remarks at the hearing by telling Kennedy that his policies were “effectively denying people the vaccine”, sharing an email from a doctor friend who expressed confusion about Covid inoculation eligibility given the FDA’s new recommendation policies.Kennedy snapped back: “You’re wrong.”The Republican senator John Barrasso, of Wyoming, also a doctor, expressed similar concerns about Kennedy’s policies. “In your confirmation hearing you promised to uphold the highest standard for vaccines,” Barrasso said. “Since then, I’ve grown deeply concerned.”During a back and forth with the Virginia senator Mark Warner, a Democrat, Kennedy falsely claimed that there are “no cuts to Medicaid” under the One Big Beautiful Bill Act – Trump’s hallmark domestic policy legislation that was signed into law in July.The congressional budget office estimates that around 7.8 million people stand to lose their health insurance over a decade, due to Medicaid changes under the law.Multiple Democrats on the committee had heated exchanges with the health secretary. Many of them pointed out the inconsistency between Kennedy’s recent support for the president’s “Operation Warp Speed” and his disparagement of the Covid-19 shot. He has previously called it the “deadliest” vaccine ever manufactured.At the hearing, Kennedy refused to acknowledge the wealth of data that shows that the Covid-19 vaccine has saved lives.“Trump has said the vaccine works, and has saved millions of lives. Your own process, on the other hand, has not been transparent,” said the Democratic senator Maggie Hassan, of New Hampshire. “You repeatedly choose to ignore data because it doesn’t match your preconceived notions and lies.” More

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      Friday briefing: What will US funding cuts on mRNA vaccines mean for the health of the world?

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      Good morning. You may have heard a saying along the lines that “when the US sneezes, the rest of the world catches a cold”. So when the US health department announced plans to cut half a billion dollars in vaccine research funding on Wednesday, the world took notice.The US is the world’s largest funder of biomedical research, but this position has become more precarious with the appointment of Robert F Kennedy Jr, a longtime vaccine sceptic, as US health secretary.This week, Kennedy has announced plans to terminate 22 federal contracts for mRNA-based vaccines, casting doubt on the safety of a technology widely credited with helping end the Covid-19 pandemic and saving millions of lives.In total the affected projects are worth nearly $500m (£376m), according to the health agency. As for Kennedy, he said: “We reviewed the science, listened to the experts, and acted.”The only problem? The scientific community in the US and around the world has overwhelmingly condemned the decision. To understand why, for today’s newsletter I spoke to Michael Head, a global health researcher at the University of Southampton. That’s after the headlines.Five big stories

      Israel-Gaza war | Benjamin Netanyahu’s office said his security cabinet had approved a plan to take over Gaza City after the prime minister earlier said Israel planned to take full control of the Palestinian territory. The decision early on Friday marks another escalation of Israel’s offensive in Gaza. Follow developments live

      Ukraine | Volodymyr Zelenskyy said ahead of an expected meeting between Donald Trump and Vladimir Putin that Europe must participate in the peace process between Ukraine and Russia. As the Kremlin refused a three-way meeting with Zelenskyy and Trump, the Ukrainian president said: “Ukraine is not afraid of meetings and expects the same brave approach from the Russian side.”

      Economy | The chancellor and prime minister will begin to foreshadow tax rises and reforms from September to prepare the country for a difficult budget that could be held in November, the Guardian has been told. A rise in gambling levies – advocated by Gordon Brown – is thought to be near-guaranteed as part of the package of tax rises.

      UK news | Amnesty International has warned the Met police against arresting participants protesting this Saturday in London in support of Palestine Action.

      Labour | The UK homelessness minister, Rushanara Ali, resigned after it emerged she evicted tenants from her east London property before increasing the rent by almost £700 a month.
      In depth: ‘The mRNA vaccines saved about 20 million lives’View image in fullscreenThe first thing to understand is that mRNA vaccines work differently from traditional ones. The latter generally introduce a weakened or inactivated part of a virus to train the immune system to recognise and fight it in the future; whereas mRNA vaccines use a molecule that tells our cells how to make a viral protein, which triggers the body’s immune responses.This technology is a scientific gamechanger, to the extent the researchers behind it won the Nobel prize in 2023. But since rising to prominence during the Covid pandemic, mRNA vaccines have been dogged by misinformation (this analysis by my colleague Nicola Davis is well worth a read.)Michael Head tells me that mRNA technology offers a very effective and adaptable approach to developing vaccines. “It’s often described as plug-and-play because you can adapt constituents of the vaccine with, for example, the latest Covid variant.”For something like a flu vaccine, researchers need to incubate the virus and grow it, which takes weeks, Head explains. “That’s fine to an extent when it comes to producing an annual vaccine like we do for seasonal influenza, but the advantage to mRNA technology is that it can be updated so quickly that it allows us to produce new vaccines or update existing vaccines quicker, which can hopefully then reduce the threat of whatever infectious disease is present.”This is crucial during a pandemic such as Covid. “The mRNA vaccines saved about 20 million lives globally in the first year of their rollout,” Head says.Why is Kennedy doing this?Kennedy once described mRNA Covid vaccines as “the deadliest vaccine ever made”. On Wednesday, he justified the health agency’s decision to terminate research by claiming that data shows mRNA vaccines “fail to protect effectively against upper respiratory infections like Covid and flu”.Kennedy offered no scientific evidence to support this – and Head said Kennedy has been spreading vaccine misinformation for years. “He has on at least one or two occasions compared vaccines to being like the Holocaust, a common anti-vaccine trope.”He has also recently falsely claimed vaccines such as the measles, mumps and rubella (MMR) jab contain “aborted foetus debris”; ordered a sweeping new study on the long-debunked link between vaccines and autism; and dismissed a panel of government vaccine experts, replacing them with his own appointees – who then voted to ban a longstanding vaccine preservative that has been a frequent target of the anti-vaccine movement despite its strong safety record.Kennedy claims he is shutting down research on mRNA vaccines and instead shifting funding to “safer, broader vaccine platforms that remain effective even as viruses mutate”, and that mRNA vaccines “encourage new mutations and can actually prolong pandemics”.It’s just not true, though. Head says variants actually tend to emerge in the absence of vaccinations, and in people with long-term infections – often those who are immunocompromised and can’t get over the virus quickly. That gives the virus more chances to multiply and mutate.“Vaccines reduce the risk of transmission and infection,” Head says, which means fewer opportunities for the virus to mutate. “So vaccines will have a protective effect against new variants emerging, rather than as Kennedy suggests.”What impact will this have?The question of the next pandemic is not if, but when. History shows pandemics happen, Head says, pointing to the 1918 flu pandemic, swine flu, Sars, and of course Covid.Head says this is especially true in our era of globalisation and human encroachment into new environments. “If you create enough opportunities, a new virus will enter human beings. There might be a scenario where it runs out of control like we saw with Covid. Or, it might be a bit more like Sars, where we were able to get it under control within a couple of months.“But again, globalisation and the mixing of people and animals makes things more challenging. And so a pandemic will happen at some point. We just don’t know when.”Technologies like mRNA vaccines, then, are vital. Head added that the potential applications go far beyond infectious disease.“There’s quite promising research on skin cancer and the potential for this technology to be applied across different areas of health,” Head says. That is another reason Kennedy’s decision is so damaging, he adds.One of Head’s research areas focuses on how funding decisions impact science such as cancer research. “It’s very early days, but we are starting to see a slightly alarming picture. It’ll be very hard for the rest of the world to fill the cancer research gaps that the US is likely to leave.”Is this a worrying time for the scientific community?There is no way to sugarcoat it; this is a particularly alarming moment for scientists. The World Health Organization coined the term “infodemic” during the pandemic to describe the overwhelming amount of misinformation that spreads during a public health crisis, Head says. Even before Covid, in 2019 the WHO listed vaccine hesitancy as one of the top 10 global health threats.“I have huge concerns that if a pandemic happened again tomorrow, whether populations in the UK, US, and around the world would trust public health decision making that would be vital to mitigate the impacts of any new pandemic. So the role of misinformation is significant and it can be very severe,” Head warned.“It does not help that some of the most powerful people, like US president Donald Trump and Robert F Kennedy Jr, are making poor quality comments on vaccination because that does have an impact on population level decision making.”Some of Head’s research has looked into vaccine uptake in Ghana during the pandemic. The study found that political views played a big role in whether someone agreed to receive a Covid vaccine.“​​The government was saying, go and get vaccinated, please, but there was a fair amount of anti-government sentiment at the time. And hesitancy was greater if you voted for the opposition and therefore trusted the government messaging less. So there are lessons to be learned on who delivers the messaging to get your vaccine, and how to address that lack of trust in governance,” Head said.For now, the world holds its breath … and hopes no one sneezes.skip past newsletter promotionafter newsletter promotionWhat else we’ve been readingView image in fullscreen

      Patrick Barkham’s piece about the recent hopeful surge of some wildlife is both a joyous celebration of animals’ resilience and a call for us to give them a helping hand. Lucinda Everett, newsletters

      I love this ranking of Daniel Day-Lewis films, and to learn that the triple Oscar winner has retired from acting, and returned twice. Aamna

      We asked our readers to share the strangest things they’ve found in a new home, and they didn’t disappoint. Forgotten placenta, anyone? Lucinda

      This story by my colleague Mark Townsend is extraordinary: it pieces together, using intelligence reports and witness testimony, how the RSF paramilitary began a massacre described as “genocidal” in Zamzam refugee camp. Aamna

      Daniel Boffey examines how David Lammy is wooing JD Vance, from inviting the US vice-president to pray with him, to shedding tears over his memoir. Lucinda
      SportView image in fullscreenTennis | Ahead of the Cincinnati Open, Emma Raducanu told Tumaini Carayol in an exclusive interview that she believes her new coaching partnership with Francisco Roig can help to take her game to the next level.Football | Liverpool have agreed a fee of £46.3m plus add-ons with Al-Hilal for Darwin Núñez. The Uruguay international is expected to complete a move to the Saudi Pro League once personal terms have been finalised.Cricket | The leader of the Tech Titans consortium that has bought 49% of London Spirit believes the Hundred will become a multibillion-dollar competition to rival the Indian Premier League.The front pagesView image in fullscreenThe Guardian print edition reports “Netanyahu defies warnings over taking military control of all Gaza”. “Minister resigns over rental ‘hypocrisy” – that’s the Telegraph while the i paper expands on that: “UK’s minister for homelessness quits after she’s caught ejecting tenants and hiking rent”. “Minister for hypocrisy is forced to quit” the Mail delights. “Single-sex spaces ‘off limits to trans women’” says the Times. “Weight loss pill ‘on NHS’” and “Pill for weight loss on NHS” – the Mirror and Express both says it’s a possibility. Deep breath needed before reading the FT’s headline aloud: “BoE lowers rates but tight vote forces investors to rein in bets on more cuts”. “He’s our brave little miracle” reports the Metro, about a lifesaving “world-first operation” on a little boy.Something for the weekendOur critics’ roundup of the best things to watch, read, play and listen to right nowView image in fullscreenMusicAmaarae: Black Star | ★★★★☆Weaving elements of house, trance and EDM into Afrobeats rhythms and spiky rap cadences, the Ghanaian-American singer’s slick take on a club record is deliriously in love with wealth, celebrity and all the power it affords. But there is a difference between Amaarae and the other stars fixated on such topics: for her, glamour is a side quest and love is the motive. Shaad D’SouzaTVLucy Letby: Beyond Reasonable Doubt? | ★★★★★
      Neonatal nurse Lucy Letby became, in tabloid parlance, “Britain’s worst child serial killer” when she was convicted in 2023 of seven murders and seven attempted murders of infants in her care. This brilliantly cogent documentary, which forces sentiment aside and unpacks the science and statistics around the most contested pieces of evidence, covers more ground more meticulously in an hour than any documentary I’ve seen in recent years, and perhaps ever. Lucy ManganFilmThe Kingdom | ★★★★☆
      Lesia, a moody 15-year-old, is sent to her mob boss father’s luxurious and fortified family compound , and she is thrilled when she quickly becomes lieutenant. There are fierce and overwhelmingly authentic performances from first-time actors in Julien Colonna’s intensely atmospheric, absorbing and exciting drama. Peter BradshawGamesTime Flies | ★★★★☆
      This perception-warping bug puzzler reimagines the inevitably short lifespan of a housefly as an absurd tragedy – by providing the soon-to-perish pest with a bucket list. Over the course of roughly a minute, players buzz around minimalist 2D environments trying to make those last wishes come true. By blending this thinky thesis with playful mechanics, it supplies a lighthearted canvas for players to engage with existentialism for an hour or two. Sarah ThwaitesToday in FocusView image in fullscreenInside China’s fast-fashion factories as a US trade war loomsThe Guardian’s senior China correspondent, Amy Hawkins, visits factories threatened by US tariffs in Guangzhou, south China, as the deadline for a US-China trade agreement approaches with no deal yet in sight.Cartoon of the day | Martin RowsonView image in fullscreenThe UpsideA bit of good news to remind you that the world’s not all badView image in fullscreenLynx – shy wild cats no bigger than a Labrador – became extinct in Britain 1,300 years ago thanks to hunting and habitat loss. But a paper published in the Journal of Environmental Management says the animals could thrive in Northumberland’s Kielder Forest area. The paper found that releasing 20 lynx over several years would eventually create a healthy population of about 50 animals, bringing benefits like helping to curb the overpopulation of deer in woodlands. According to the researchers, Kielder Forest is the only area of England and Wales with enough woodland for lynx to thrive. But thankfully locals are keen on the plan, with 72% of people in the project area supporting reintroduction.Sign up here for a weekly roundup of The Upside, sent to you every SundayBored at work?And finally, the Guardian’s puzzles are here to keep you entertained throughout the day. Until tomorrow.

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      DoJ drops charges against Utah doctor accused of destroying Covid vaccines

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      The US Department of Justice dropped charges on Saturday against Michael Kirk Moore, the Utah doctor accused of destroying more than $28,000 worth of government-provided Covid-19 vaccines and administering saline to children instead of the shot.Pam Bondi, the US attorney general, announced the news in a statement on the social media platform X, saying the charges had been dismissed under her direction.“Dr Moore gave his patients a choice when the federal government refused to do so,” Bondi said. “He did not deserve the years in prison he was facing.”According to a 2023 press release from the US attorney’s office in Utah, Moore distributed at least 1,937 fraudulent vaccination record cards in exchange for either direct payment or required donations to a specific charity. The minors he gave saline shots to were under the impression, at the request of their parents, that they were receiving a Covid-19 shot. Moore ran the operations from a plastic surgery center in Midvale, Utah, and was charged, along with three other co-defendants, with conspiracy to defraud the United States.Far-right congresswoman Marjorie Taylor Greene thanked Bondi in a statement on X and called Moore a “hero who refused to inject his patients with a government-mandated unsafe vaccine”.The Utah senator Mike Lee also weighed in, saying on X that he was glad Moore could remain a free man and that countless Americans endured lies and lockdowns during the pandemic.Moore was indicted by the justice department in 2023. He pleaded not guilty to the charges, which also included conspiracy to convert, sell, convey and dispose of government property, and the conversion, sale, conveyance and disposal of government property.The fake vaccination records were sold under Moore’s scheme for $50 each, and operations allegedly ran between May 2021 and September 2022. Attorneys for Moore argued that the regulations set at the time by the Centers for Disease Control and Prevention (CDC) were unconstitutional.The charges against Moore were brought in when Joe Biden was president, but Covid-19 conspiracists and skeptics have been embraced in the new administration under Trump.Recently, the Trump administration canceled a $766m award to Moderna on the research and development of H5N1 bird flu vaccines, and officials announced new restrictions and regulations for Covid mRNA vaccines.The US health secretary, Robert F Kennedy Jr, who has for decades baselessly sowed doubt about vaccine safety, contrary to scientific research, thanked Moore in a statement on X back in April.“Dr Moore deserves a medal for his courage and his commitment to healing,” Kennedy Jr said. More

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      Pregnant doctor denied Covid-19 vaccine sues Trump administration

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      A pregnant physician who was denied a Covid-19 vaccine is suing the Trump administration alongside a group of leading doctors associations, charging that the administration sought to “desensitize the public to anti-vaccine and anti-science rhetoric”, according to their attorney.The lawsuit specifically takes aim at health secretary Robert F Kennedy’s unilateral decision to recommend against Covid-19 vaccines for pregnant women and healthy children.Kennedy’s announcement circumvented expert scientific review panels and flouted studies showing pregnant women are at heightened risk from the virus, and made it more difficult for some to get the vaccine.“This administration is an existential threat to vaccination in America, and those in charge are only just getting started,” said Richard H Hughes IV, partner at Epstein Becker Green and lead counsel for the plaintiffs in a statement.The American Academy of Pediatrics, American College of Physicians and American Public Health Association are among a list of leading physicians associations named as plaintiffs in the lawsuit.“If left unchecked, secretary Kennedy will accomplish his goal of ridding the United States of vaccines, which would unleash a wave of preventable harm on our nation’s children,” said Hughes. “The professional associations for pediatricians, internal medicine physicians, infectious disease physicians, high-risk pregnancy physicians, and public health professionals will not stand idly by as our system of prevention is dismantled. This ends now.”In late May, Kennedy announced that the Centers for Disease Control and Prevention (CDC) would no longer recommend Covid-19 vaccines for healthy children or pregnant women. The announcement, made on social media, contradicted a raft of evidence showing pregnant women and infants are at especially high-risk from the disease, including from the administration’s own scientific leaders.In June, Kennedy went further by firing all 17 sitting members of a key vaccine advisory panel to the CDC. The advisory panel is a key link in the vaccine distribution pipeline, helping to develop recommendations insurers use when determining which vaccines to cover.That panel met for the first time in late June. Members announced they would review both the childhood vaccine schedule and any vaccines that had not been formally reviewed in seven years. They also recommended against a long-vilified vaccine preservative, in spite of a lack of evidence of harm.The news comes amid the largest annual measles case count in 33 years, and amid reports of more parents seeking early vaccination for their children, fearing vaccines will go into shortage or no longer be covered by insurance. More