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      RFK Jr says they are poisoning us, influencers call them unnatural – but what is the truth about seed oils?

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      It’s curious that something so bland could cause so much controversy. Most of us have a bottle of seed oil, normally called vegetable oil in the UK, in our kitchens – a nearly tasteless but very useful fat that has been a commonplace cooking ingredient for decades.And yet this previously unremarkable golden liquid has sparked online furore and vicious debate. Nutrition influencers on social media have described it as “toxic”, “inflammatory”, “unnatural” and the root cause of the obesity epidemic.The US health secretary Robert F Kennedy Jr, who has caused controversy with his views on subjects from vaccines to fluoride in drinking water, has said the population is being “unknowingly poisoned” by seed oils and urged people to revert to “traditional” fats such as butter, lard and beef dripping for better health.Last month the Wall Street Journal reported that fast food chains were promoting their shift away from seed oils after Kennedy’s criticisms. He even made a televised visit to a branch of Steak ’n Shake to praise its decision to cook fries in beef tallow instead.So should we really be ditching our bottles of vegetable and sunflower oils and covering everything in lard?Seed oils have been in widespread use since about the 1950s and, as well as being used for home cooking, are also in many ultra-processed foods. They include rapeseed (known as canola in the US and generally labelled as vegetable oil in the UK), sunflower, soya bean, corn, grapeseed, rice bran, sesame and safflower. While you can buy cold-pressed seed oils, the most common production method involves using a solvent (normally hexane) to extract the oil from the plant. It is correct that hexane is a toxic substance, but it is almost entirely removed from the final product by the refining process – the EU allows a maximum residual limit of 1mg per kilo.The refining process includes bleaching and deodorising, both of which critics have jumped on to claim that seed oil is “unnatural” and therefore “bad”.Tom Sanders, emeritus professor of nutrition and dietetics at King’s College London, who has spent his career researching dietary fat and health, explains: “The processing actually takes out potentially toxic material.”Sarah Berry, professor of nutritional sciences at King’s, agrees: “The end product, in my opinion, is very safe to eat.”The next allegation against seed oils is that they are “inflammatory”. This assumption is based on a fundamental misunderstanding of the science, says Berry.View image in fullscreenSeed oil critics claim that the type of omega-6 fatty acid present in them (called linoleic acid) can be inflammatory, whereas omega-3 – the other essential polyunsaturated fatty acid, found in foodstuffs such as oily fish, flaxseed and chia seeds – can reduce inflammation.“Because the enzymes used to convert omega-3 into anti-inflammatory chemicals are the same ones used to convert omega- 6, their argument is that having too much seed oil will mean the enzymes are stolen away from the omega-3,” says Berry.“This isn’t true. It’s true from a theoretical biochemical pathway. It’s true in mice upon unrealistic stimuli. But it is absolutely not true in humans.” In fact, randomised, controlled trials show that linoleic acid has either a neutral or, in most studies, an anti-inflammatory effect in humans.“The idea that linoleic acid is some sort of toxic thing is absolute nonsense,” says Sanders. “It’s an essential nutrient. Of the essential fatty acids it’s the most important one. If you’re deficient, it impairs immune function and platelet function doesn’t work.”It also has a potent cholesterol-lowering effect, says Berry, who is chief scientist at nutrition company Zoe. “It has been shown to reduce blood cholesterol significantly. Because of this and based on the current evidence I would say that not only are seed oils not bad for us, they are a healthy part of our diet.”Sanders attributes much of the decline in cardiovascular disease we’ve seen in the past 50 years to our increased consumption of seed oils. A few weeks ago, a study that followed 200,000 adults over 33 years found that those who replaced a tablespoon of butter a day with the same amount of plant-based oil such as soya bean or rapeseed had a 17% reduction in risk of death from all causes. The study, which was published in JAMA Internal Medicine also found a 17% reduction in risk of death from cancer.“Our study found that higher butter intake was associated with increased deaths from all causes and cancer, while higher intake of plant-based oils was associated with lower deaths from all causes, cancer and cardiovascular disease,” said lead study author Yu Zhang, a graduate student at Harvard TH Chan School of Public Health.Priya Tew, from Dietitian UK, says some of the confusion might have come from a 1960s study: “It showed men with heart disease had a higher intake of seed oils. But this was through margarines that also contain trans fats, which we know increase the risk of heart disease.”A similar logic applies to the argument that, as our intake of seed oils has risen – which it has more than 200-fold over the past 50 to 70 years – so too have our rates of chronic disease.“Association does not mean causality,” says Berry. “Think what else has changed; our food landscape is almost unrecognisable compared with 70 years ago. It’s estimated 60% of the seed oils we consume come from ultra-processed food which has many other chemicals that are unhealthy for us and processes that affect the healthfulness of the food.”In other words, it’s not the seed oil that’s the problem.Berry’s recent statements about seed oils have landed her in hot water. After appearing on a podcast explaining that seed oils are healthy, she received relentless hate mail, including being told she’s “the most hated scientist in America”.“It nearly got to the point where I was going to stop speaking out on the topic so I didn’t have to be subjected to such horrible comments and meanness. But then I thought, that’s exactly what they want. They want to shut down the real evidence, so it just galvanised me to speak out about it even more.”As always, with nutrition, it’s better to consider overall diet than to hyper-fixate on one ingredient. But these kind of messages don’t tend to get as much traction. “Human nature is such that we are more susceptible to risk and scare headlines,” Berry says. “They’re going to get more clicks than a balanced, boring nutrition scientist like myself saying seed oils are fine as part of a balanced diet.”Sanders says you don’t have to ditch your seed oils and you shouldn’t swap them for butter or lard. “The seed oil scare is all just gossip. It’s not based on any good science at all.” More

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      When the physicists need burner phones, that’s when you know America’s changed | John Naughton

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      At international academic conferences recently, one sees an interesting trend. Some American participants are travelling with “burner” phones or have minimalist laptops running browsers and not much else. In other words, they are equipped with the same kind of kit that security-conscious people used to bring 15 years ago when travelling to China.So what’s up? Well, these academics have a finger on the pulse of Trump’s America, and are concerned about what might happen when they return home. They’ve read on Robert Reich’s Substack about the French scientist who was prevented from entering the country because US Border Patrol agents had found messages from him in which he had expressed his “personal opinion” to colleagues and friends about Trump’s science policies.Or they’ve heard about Dr Rasha Alawieh, a kidney transplant specialist and professor at Brown University who was trying to return to the US after visiting relatives in Lebanon. She was deported, reports Reich, “despite having a valid visa and a court order” blocking her removal. “Federal authorities alleged that they found ‘sympathetic photos and videos of prominent Hezbollah figures’ in her phone and that she attended the funeral for the leader of Hezbollah in February.”And they also know about Mahmoud Khalil, a Columbia University graduate, whom – though he is a legal permanent resident of the US and has not been charged with a crime – the government is trying to deport because he had participated in pro-Palestinian demonstrations at Columbia.Those pro-Gaza demonstrations so irked the Trump regime that it demanded the return of $400m of federal research funding. When Columbia sought a meeting to discuss the matter, it received a letter setting out the conditions that it would have to accept before the government would deign to talk. These included a stipulation that Columbia must “begin the process of placing the Middle East, South Asian, and African Studies Department under academic receivership for a minimum of five years”.The bullying of Columbia is the canary in the coalmine which reveals the Trump-Musk junta has it in for American universities. There are two reasons for their hostility. The first is that, as elite institutions devoted to freedom of inquiry and the telling of uncomfortable truths, they are anathema to the new autocrats in Washington. The second is that some of them (the so-called Ivy League) are fabulously wealthy, being for the most part hedge funds with nice universities attached. And if there’s one thing that Donald Trump cannot abide, it is large pots of money that he and his ghastly tribe can smell but not touch. So if the aloof trustees of Harvard, Princeton, Yale et al think that their august institutions lie beyond his reach, perhaps they should understand that Trump looks on them much as Henry VIII looked on the rich monasteries of his heyday.Many teachers and researchers in US universities are now fearful of what lies ahead. No line of inquiry is safe from the raging firestorm of Maga intolerance. Many of the most vulnerable areas of inquiry lie in the health sector – LGBTQ+ medicine, epidemiology, infectious diseases, immunology, and so on. But there’s also endangered research on environmental issues and the climate crisis, socioeconomic inequality, plus the humanities, social science and astrophysics.The looming crisis in the US is beginning to remind people in Europe of the 1930s, when the UK and the US began to realise that Jewish scientists needed to be rescued from the Nazis. About 2,000 scientists and academics fled the fascist countries between 1933 and 1941, fearing for themselves or Jewish family members. Then, universities in the US and the UK made space for and welcomed a whole generation of geniuses – Albert Einstein, Enrico Fermi, Leo Szilard, Hans Bethe, Max Born, Rudolf Peierls, Francis Simon, to name just a few. Likewise, members of the Frankfurt School were rescued and installed in New York, where they became mightily critical of American capitalism but at least lived to tell their particular tale. As did Thomas Mann.Now, in a different age, there are stirrings in Europe to provide safe places for American researchers. In France, Aix-Marseille University is welcoming American scientists whose work has become untenable after the Trump administration’s cuts in certain academic sectors. The Free University of Brussels (VUB) is opening 12 postdoctoral positions for international researchers, which are open to American researchers working in socially relevant fields. The fellowships come with substantial funding (€2.5m) as part of the European Marie Skłodowska-Curie programme. It’s also aiming to attract American professors looking to relocate. VUB, with its Francophone sister university ULB, is providing 18 apartments for international researchers seeking temporary residence at the Brussels Institute for Advanced Studies.This is the beginning of something hopeful. But it also raises the question of what UK institutions are doing to meet the coming challenge. The answer, at the moment, seems to be nothing much. Perhaps that’s because most of British academia still can’t get its head around the idea that the US is now an enemy, not an ally, and that the “special relationship” is yesterday’s story.What I’ve been readingHow I accidentally got sent Trump’s Yemen textsJeffrey Goldberg’s astonishing story about the White House security leak in the Atlantic.Philosophy and fatherhoodA curious tendency among western philosophers explored in an intriguing post by Doug Muir.AI has learned to reason … … or has it? A lovely explainer by Melanie Mitchell.

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      The Guardian view on Trump and reality: from promoting alternative facts to erasing truths | Editorial

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      What does the public need to know? The Trump White House boasts of being the most transparent administration in history – though commentators have suggested that the inadvertent leak of military plans to a journalist may have happened because senior figures were using messaging apps such as Signal to avoid oversight. Last week, it released thousands of pages of documents on John F Kennedy’s assassination. Donald Trump has declared that Kennedy’s family and the American people “deserve transparency and truth”.Strikingly, this stated commitment to sharing information comes as his administration defunds data collection and erases existing troves of knowledge from government websites. The main drivers appear to be the desire to remove “woke” content and global heating data, and the slashing of federal spending. Information resources are both the target and collateral damage. Other political factors may be affecting federal records too. Last month, Mr Trump sacked the head of the National Archives without explanation, after grumbling about the body’s involvement in the justice department’s investigation into his handling of classified documents.The impact is already painfully evident. Cuts at the National Oceanic and Atmospheric Administration have affected not only climate records but also an extreme weather risk tool. The purge’s results are absurd as well as damaging. A webpage on the Enola Gay, the aircraft that dropped the atomic bomb on Hiroshima, appears to have been marked for deletion because it was mistaken for a reference to LGBTQ+ issues.Yet the disparity between the data dump on the Kennedy assassination and the removal of other material is not a contradiction. It speaks volumes about the administration’s approach to truth and knowledge, which it regards as contingent and a matter of convenience. (Tellingly, it is also axing the body that provides most federal funding to libraries.)The 1963 presidential assassination is not only an event around which multiple theories circle but one that helped feed a broader culture of conspiracy theorising and distrust in authority. That has metastatised to the bizarre and extreme claims embraced and even promoted by Mr Trump or figures around him, including birtherism, Pizzagate and QAnon. These increasingly fantastical narratives have had real-world consequences. Facts, science and rationality itself are under attack.In his first term, Mr Trump’s aides shamelessly promoted “alternative facts” while decrying actual facts as “fake news”. The Washington Post tallied more than 30,000 false or misleading claims over those four years. This time round, his administration is removing existing sources of information. Websites, datasets and other information vanished from federal health websites – such as that for the Centers for Disease Control – last month, though some has since reappeared. One scientist called it “a digital book burning”. The Union of Concerned Scientists has warned that “critically important science conducted at many US agencies, institutions, and universities [is] under increasing assault”.Ad hoc preservation of essential national information and records is usually the work of those faced with the destructive force of foreign invasions, jihadist insurgencies or dictators. But as this bonfire blazes, a motley but committed array of individuals – “nerds who care”, in the words of one – are fighting back by preserving data before it is deleted. Their admirable effort to defend the truth deserves support.

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      European universities offer ‘scientific asylum’ to US researchers fleeing Trump’s cuts

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      Laced with terms such as “censorship” and “political interference”, the Belgium-based jobs advert was far from typical. The promise of academic freedom, however, hinted at who it was aimed at: researchers in the US looking to flee the funding freezes, cuts and ideological impositions ushered in by Donald Trump’s administration.“We see it as our duty to come to the aid of our American colleagues,” said Jan Danckaert, the rector of Vrije Universiteit Brussel (VUB), in explaining why his university – founded in 1834 to safeguard academia from the interference of church or state – had decided to open 12 postdoctoral positions for international researchers, with a particular focus on Americans.“American universities and their researchers are the biggest victims of this political and ideological interference,” Danckaert said in a statement. “They’re seeing millions in research funding disappear for ideological reasons.”The university is among a handful of institutions across Europe that have begun actively recruiting US researchers, offering themselves as a haven for those keen to escape the Trump administration’s crackdown on research and academia.Since Trump took power in late January, researchers in the US have faced a multipronged attack. Efforts to slash government spending have left thousands of employees bracing for layoffs, including at institutions such as Nasa, the Centers for Disease Control and Prevention, and at the National Oceanic and Atmospheric Administration, the US’s pre-eminent climate research agency. The government’s targeting of “wokeism” has meanwhile sought to root out funding for research deemed to involve diversity, certain kinds of vaccines and any mention of the climate crisis.In France, the director of the prestigious Pasteur Institute in Paris, Yasmine Belkaid, said it was already working to recruit people from across the Atlantic for work in fields such as infectious diseases or the origins of disease.View image in fullscreen“I receive daily requests from people who want to return: French, European or even Americans who no longer feel able to do their research or are afraid to do it freely,” Belkaid told the French newspaper La Tribune. “You might call it a sad opportunity, but it is an opportunity, all the same.”The sentiment was echoed by France’s minister for higher education and research, Philippe Baptiste, in a recent letter that called on research institutions to send in proposals on how best to attract talent from the US. “Many well-known researchers are already questioning their future in the US,” he said. “Naturally, we wish to welcome a certain number of them.”On Thursday, the Netherlands said it was aiming to swiftly launch a fund to attract researchers to the country.While the fund would be open to people of all nationalities, the country’s education minister, Eppo Bruins, hinted at the tensions that have gripped US academia in announcing the plans.“There is currently a great global demand for international top scientific talent. At the same time, the geopolitical climate is changing, which is increasing the international mobility of scientists,” Bruins said in a letter to parliament.“Several European countries are responding to this with efforts to attract international talent,” he added. “I want the Netherlands to remain at the vanguard of these efforts.”The Dutch effort comes after France’s Aix-Marseille University said it had set up a programme – titled Safe Place for Science – that would put aside funding for more than two dozen researchers from the US for three years.skip past newsletter promotionafter newsletter promotion“We wish we didn’t have to do this,” said Éric Berton, the university’s president. “We’re not looking to attract researchers. But we were quite indignant about what was happening and we felt that our colleagues in the US were going through a catastrophe … we wanted to offer some sort of scientific asylum to those whose research is being hindered.”Two weeks after the programme was launched there have been about 100 applications, with researchers from Yale, Nasa and Stanford among those who have expressed interest. The university continues to receive about 10 applications a day, said Berton, many of them from researchers involved in studying climate, health or social sciences.Berton said he hoped universities across Europe would join his in providing a safe space for researchers. “I think that we need to realise the historic moment we’re living through and the serious, long-term consequences this could have,” he said. “Europe must rise to the occasion.”At VUB, the opening of the 12 postdoctoral positions was also aimed at acknowledging the global impact of Trump’s crackdown. Two research projects in which the university was involved – one delving into youth and disinformation and another investigating the transatlantic dialogue between the US and Europe – had been cancelled due to “changed policy priorities”, it said.For the university in Brussels, the openings were also a vindication of sorts. In a 2016 interview with Fox News, Trump had sought to characterise life in Brussels as akin to “living in a hellhole”, falsely accusing migrants in the city of failing to assimilate.“At the time, the statement elicited many emotional reactions in Europe,” the university said. “This gives additional symbolic meaning to the VUB initiative.” More

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      A French university is offering ‘scientific asylum’ for US talent. The brain drain has started | Alexander Hurst

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      In six weeks, the Trump administration’s “rapid scheduled disassembly” of American science has been as sharp and deep as its trashing of the US’s alliances and goodwill; Earth science, weather forecasting and early warning systems, medical research (including cancer research), Nasa. Academic grants more broadly have been cut, paused and subject to review for a long list of banned words (including such contentious terms as “political” and “women”).This has caused universities across the country to reduce their intake of PhD students, medical students and other graduate students, introduce hiring freezes and even rescind some offers of admission. More than 12,500 US citizens currently in other countries on Fulbright research grants recently had their funding paused, along with 7,400 foreign scholars currently hosted in the US, leaving them financially stranded. And, when it came to one foreign academic visiting the US, detaining them and refusing them entry.Even more worryingly, the administration is specifically targeting some universities, including pulling $400m in funding from Columbia University, and $800m from Johns Hopkins, forcing it to lay off 2,000 people. Furthermore, the legally dubious arrest and detention of Mahmoud Khalil, and the cancelling of his green card, is sure to have a chilling effect on foreign students and researchers already in the US – and on the desire of others to go there in the future. As Christina Pagel, a German-British professor at University College London, writes: “This isn’t chaos.” Instead, the attacks on research appear to follow a three-pronged objective: to forcibly align science with state ideology; undermine academic independence and suppress dissent; and maintain geopolitical and economic goals.The Saturn V rockets that took US astronauts to space – and eventually the moon – in the 1960s owed their existence to Operation Paperclip, which brought 1,500 former Nazi scientists (such as Wernher von Braun, the former director of Nasa’s Marshall Space Flight Center) to the US. In the week after Donald Trump’s election, I wondered whether the German philosopher Jürgen Habermas may inadvertently get his wish (of a Europe that unified through opposition to the US) and suggested that Europe position itself to reverse the decades-long transatlantic brain drain by welcoming highly educated American researchers and scientists who were sure to find themselves under attack. This time, there is no moral quandary about it, no Nazi pasts to ignore; only as much advantage to be gained as can be in a world where the EU must hold the ground for liberal democratic society, joined by Canada to the west, and Japan, South Korea, Australia and New Zealand to the east.To some extent, EU governments and institutions are already picking up on the opportunity. For example, on 7 March, the University of Aix-Marseille announced Safe Place for Science, a three-year, €15m programme to bring 15 American scientists working in climate, health and astrophysics to its campus. According to a university spokesperson, more than 60 applications have been received, 30 of them coming within the first 24 hours. The university indicated that it has been in contact with other universities and the French government about expanding “scientific asylum” on both a national and European level, and to help coordinate welcoming and relocating different researchers.US federal government spending on all research and development (R&D) totalled roughly $195bn in 2024. That sounds imposing, but let’s put it into greater context. As of 2023, US GDP was $27.7tn and EU GDP was $26.5tn, when adjusted for purchasing power parity. Taken as a whole, both polities are roughly the same economic size. Let’s imagine that the EU were to put real money on the table to lure science of all kinds out of the US and to the continent. It wouldn’t need to match $195bn, euro for dollar, in part because more than half the US total is defence R&D, and the EU is already boosting defence spending … bigly. So, say it just picked a bold, round number that lends itself well to narrative, storytelling and headlines, and is enough to rope in the cuts happening in the US.A sum of €25bn a year would represent just under 0.1% of the EU’s GDP, and even less if the UK, Norway and Switzerland (all of which participate in the Horizon Europe research funding programme) were included. As it is, R&D spending in the EU lags behind the US – and a report ordered by the European Commission’s research department recently recommended more than doubling Horizon Europe’s €95bn, seven-year budget. What I’m suggesting goes further, yes. But not only is it well within the EU’s ability to afford, it would ultimately pay for itself: research found that non-defence R&D spending returned 200% for the US during the postwar period.But let me push the boundary of fantastical again, and suggest that the EU may lure not just American researchers, but American universities themselves. According to the Cross Border Education Research Team, US universities maintain 29 actual campuses in Europe (and far more if you include “centres” and study abroad programmes). There are dozens of American colleges and universities with enormous endowments that regularly splash out hundreds of millions of dollars at a time on new buildings. If US crackdowns (like the recent demands made of Columbia) on academic freedom, funding, and foreign students and faculties become more frequent, they may find the idea of second campuses in Europe tempting indeed.

      Alexander Hurst is a Guardian Europe columnist

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      Russia will ‘undoubtedly’ discuss future Mars flights with Musk, Putin envoy says

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      Russian officials expect to hold talks with Elon Musk soon about space travel to Mars, Vladimir Putin’s international cooperation envoy said on Tuesday. The envoy’s comments, which Musk has not confirmed, also stated that Russia wanted to expand its cooperation with the US on space projects.“I think that there will undoubtedly be a discussion with Musk [about Mars flights] in the near future,” Kirill Dmitriev said at a business forum in Moscow, going on to praise Musk’s efforts to push the boundaries of human achievement.The proposed talks would once again put Musk, the world’s richest man and a senior adviser to Trump, in an outsized and largely unaccountable role in international politics. Musk has joined in on White House calls with international leaders since Donald Trump’s reelection, and prior to his new role in the administration reportedly was in regular contact with Putin.Musk’s ownership of SpaceX and control of the Starlink satellite communications system have increasingly allowed him to take on the role of power broker in space travel and international telecommunications. In the US, Nasa has come to rely on SpaceX for the majority of its launches, and recently fired workers have raised alarms about his growing sway over the agency. Musk has also used his leverage over international telecoms to assert his political influence, including limiting Ukraine’s military use of Starlink during the Russia-Ukraine war and recently clashing with Poland’s foreign minister over the technology.Dmitriev, who was named by Putin last month as his special envoy on international economic and investment cooperation, also claimed on Tuesday that Russia’s “enemies” were trying to derail Trump’s efforts to restore a dialogue with Russia. His remarks came as Trump held a call with Putin on Tuesday to discuss a potential ceasefire in Ukraine and eventual end to hostilities after Russia invaded the country in 2022.Dmitriev said Russia wanted to work with Musk as part of Moscow’s efforts to strengthen and develop Russia’s space agency, Roscosmos, and state nuclear corporation Rosatom. Dmitriev stated he was in touch with Roscosmos, Russian businesses and the American Chamber of Commerce in Russia.skip past newsletter promotionafter newsletter promotionRussia said in 2022 it would start work on its own Mars mission after the European Space Agency (ESA) suspended a joint project in the wake of Putin’s decision to send tens of thousands of troops into Ukraine. More

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      ‘It’s back to drug rationing’: the end of HIV was in sight. Then came the cuts

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      This year the world should have been “talking about the virtual elimination of HIV” in the near future. “Within five years,” says Prof Sharon Lewin, a leading researcher in the field. “Now that’s all very uncertain.”Scientific advances had allowed doctors and campaigners to feel optimistic that the end of HIV as a public health threat was just around the corner.Then came the Trump administration’s abrupt cuts to US aid funding. Now the picture is one of a return to the drugs rationing of decades ago, and of rising infections and deaths.But experts are also talking about building a new approach that would make health services, particularly those in sub-Saharan Africa, less vulnerable to the whims of a foreign power.The US has cancelled 83% of its foreign aid contracts and dismantled USAid, the agency responsible for coordinating most of them.Many fell under the President’s Emergency Plan for Aids Relief (Pepfar) programme, which has been the backbone of global efforts to tackle HIV and Aids, investing more than $110bn (£85bn) since it was founded in 2003 and credited with saving 26 million lives and preventing millions more new infections. In some African countries it covered almost all HIV spending.View image in fullscreenThere is a risk, says Lewin, director of Melbourne University’s Institute for Infection and Immunity and past president of the International Aids Society, of “dramatic increases in infections, dramatic increases in death and a real loss of decades of advances”.There is no official public list of which contracts have been cancelled, and which remain. It appears that virtually no HIV-prevention programmes funded by the US are still in operation, save a handful principally providing drugs to stop pregnant women passing on the infection to their babies. Countries report disruption to the most basic measures, such as condom distribution.Some treatment programmes have been spared, but not those whose focus conflicted with the Trump administration’s war on “gender ideology” or diversity, equity and inclusion (DEI), such as those working with transgender communities. Doctors, nurses and other healthcare workers have been laid off, while worried patients are hoarding drugs or stretching supplies, according to UNAids surveillance. UNAids itself has lost more than half of its funding.Even programmes that have survived the cull have faced turmoil since February, with instructions to stop work rescinded but with no certainty that funding will continue.View image in fullscreenIn only one example, the Elizabeth Glaser Paediatric Aids Foundation says it has had to halt HIV treatment for 85,000 people in Eswatini, including more than 2,000 children, and tests for thousands of pregnant women and babies to prevent transmission and begin life-saving medication.Access to drugs represents an “immediate crisis”, Lewin says. “If people with HIV stop the medications, then not only do they get sick themselves, which is tragic, but they also then become infectious to others.”As clinics on the frontline of treating the disease scrabble to secure access to basic drugs, scientists at this month’s Conference on Retroviruses and Opportunistic Infections in San Francisco were hearing that HIV might soon be preventable with a once-a-year injection.The drug lenacapavir was already generating huge excitement in the field, after trial results showed that a six-monthly jab could prevent HIV. New results from the manufacturer Gilead suggest that a tweak to the formula and how it is given could see its protective effects last even longer.Nevertheless, Lewin says, the mood at the meeting, packed with many of the world’s leading HIV specialists, was “dire”.As well as programme cancellations, there are “huge concerns around science and what’s going to happen to the [US] National Institutes of Health, [whose] funding of science has been so significant on every level”, she says.Some scientists in receipt of US funding have been told to remove their names from DEI-linked research, she says, even though DEI is fundamental to the HIV response.View image in fullscreen“I don’t mean that in a sort of touchy-feely way, I mean that’s what we need to do: you need to actually get those treatments to these diverse communities.”In 2022, 55% of all new HIV infections were within “key populations”, such as gay men, other men who have sex with men, sex workers, transgender people, prisoners and people who inject drugs.Prof Linda-Gail Bekker, of South Africa’s Desmond Tutu Health Foundation, has seen US funding for three trials of potential HIV vaccines involving eight countries cancelled and only reinstated after an appeal to the US supreme court.“We’re running around like chickens without heads to at least get one going, because the vaccines are sitting in the fridge and will expire,” she says.She led the lenacapavir trial that showed it offered 100% protection to young women in sub-Saharan Africa, but now worries about HIV/Aids prevention “falling off the radar completely”.The global community had been making headway towards the United Nations’ goal of ending Aids by 2030, she says, with a five-year plan to use “amazing new innovative tools and scale them up”, which would have led to “less dependence on foreign aid and more self-reliance” as new infections fell and attention shifted to maintaining treatment for people with HIV.“All of that is hugely at risk now because, without these funds, our governments will have to step up but they will concentrate on treatment,” she says. “We know they will do that, because that is what we did for the first 30 years.”Efforts to control Aids were entering “the last mile”, which was always likely to be more expensive, she says. “The people who were happy to come into health facilities, they would have come into health facilities.”It would be difficult to rely on government funding to reach the remaining groups, she says, not only because of fewer resources but also because in some countries it means targeting groups whose existence is illegal and unrecognised, such as sex workers or sexual minorities, and young girls may be reluctant to use government clinics if they are not supposed to be sexually active.“I feel like the odds are very stacked against us,” says Bekker, adding: “We’re obviously going to have to re-programme ourselves [and] formulate a different plan.”Pepfar had pledged funding to the Global Fund to Fight Aids, Tuberculosis and Malaria, to deploy 10m doses of lenacapavir in low-income countries. While the Global Fund has promised to maintain its commitment, it might receive fewer than the planned number of doses, Bekker fears.“Six months ago, I was saying the best thing we can do with lenacapavir is offer it to everybody in a choice environment. [Now] I think we’re gonna have to say who needs [injectable] prep,” she says, “and the rest have to do the best they can.“How do we make that decision? And what does that look like? It is back to sort of rationing.“When we started ARVs [antiretroviral drugs] way back in 2000,” Bekker recalls, “you would go, ‘you get treatment; you don’t, you don’t, you don’t’.“It feels terrible … but you have to get over that. You have to say it will be infection-saving for some people. And we’ve got to make it count.”View image in fullscreenFor Beatriz Grinsztejn, president of the International Aids Society, the disruption is critical and threatens many vulnerable people. But, she adds, it could present “an important opportunity for ownership – otherwise we are always left in the hands of others”.She worries about the impact of cuts to funding on younger scientists, with their potential loss from the research field “a major threat for the next generation”. But, she adds, the HIV community is “powerful and very resilient”.There have already been calls for new ways of doing things. It is “time for African leadership”, members of the African-led HIV Control Working Group write in the Lancet Global Health. There are now plans for Nigeria to produce HIV drugs and tests domestically.Christine Stegling, deputy director of UNAids, says it began “a concerted effort” last year to develop plans with countries about how their HIV programmes could become more sustainable domestically “but with a longer timeframe … now we are trying to do some kind of fast-tracking”.Governments are determined, she says, but it will require fiscal changes either in taxation or by restructuring debt.The goal of ending Aids by 2030 is still achievable, Stegling believes. “I think we have a very short window of opportunity now, in the next two, three months, to continue telling people that we can do it.“I keep on reminding people, ‘look, we need to get back to that same energy that we had when people were telling us treatment can’t be available in the global south, right?’ And we didn’t accept it. We made it happen.“We have national governments now who are also very adamant, because they can see what can happen, and they want to make it happen for their own populations.” More

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      View image in fullscreenTechno-optimism – the belief that technology will usher in a golden age for humanity – is in vogue once more.In 2022, a clutch of pseudonymous San Francisco artificial intelligence (AI) scenesters published a Substack post entitled “Effective Accelerationism”, which argued for maximum acceleration of technological advancement. The 10-point manifesto, which proclaimed that “the next evolution of consciousness, creating unthinkable next-generation lifeforms and silicon-based awareness” was imminent, quickly went viral, as did follow-up posts.Effective accelerationism, or “e/acc”, exploded from being a fringe movement dedicated to pushing back against AI extinction-fearing “doomers” to being namechecked by major Silicon Valley CEOs such as Garry Tan, the CEO of start-up accelerator Y Combinator; Sam Altman, head of OpenAI; Marc Andreessen, the billionaire software engineer; and Elon Musk.In 2023, Andreessen issued his Techno-Optimist Manifesto, expanding beyond the e/acc’s focus on AI to encompass all questions of technological progress. “We are told to be angry, bitter, and resentful about technology,” he writes, yet previously and for hundreds of years, we had glorified it. The enemies of techno-optimism are, he says, statism, economic planning and socialism. Andreessen tells us: “Technology is the glory of human ambition and achievement, the spearhead of progress, and the realization of our potential … It is time, once again, to raise the technology flag.”And last year saw the release of the Techno-Humanist Manifesto from the Roots of Progress Institute and Jason Crawford, who makes similar arguments for the liberatory power of technology, while also arguing that anything that can be for profit should be.But where is the left in all this?One would think that in the wake of the Covid-19 pandemic, which saw the market flounder and the state rise to the occasion with responses such as Operation War Speed’s vaccine development and rollouts, the left would be crowing about how it produced technological progress far better than all this market fundamentalism.It was the embrace of varieties of economic planning that produced the innovation needed to defeat the virus. For decades, large firms had gotten out of the business of vaccine development because it was insufficiently profitable. The mRNA vaccine delivery vehicle that is now recognized as revolutionary for the life sciences far beyond Covid had been sitting on the shelf for about a decade, spurned by uninterested, risk-averse investors.At the start of the pandemic, big pharma remained wary that transmission might fizzle out and they’d be left having spent billions on a white elephant. Instead, it was the advance purchase agreements, subsidies and coordination of the government – which does not need to turn a profit – via the Biomedical Advanced Research and Development Authority (Barda) and Operation Warp Speed that delivered the vaccine and saved the world.Meanwhile, free-market driven distribution of PPE, ventilators, medical fridges and oxygen had produced little more than corruption, bottlenecks and irrational allocation to those who could pay the highest price – not allocation where it was most needed. It was only when the White House deployed the Defense Production Act to enable the government to takeover distribution that the market’s deadly mess was cleared up.@font-face{font-family:Guardian Headline Full;src:url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.woff2) format(“woff2”),url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.woff) format(“woff”),url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.ttf) format(“truetype”);font-weight:300;font-style:normal}@font-face{font-family:Guardian Headline Full;src:url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-LightItalic.woff2) format(“woff2”),url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-LightItalic.woff) 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      The left should be proudly flaunting the record of governments around the world in responding to Covid
      The left should be proudly flaunting the record of governments around the world in responding to Covid. It should make the case that all major technological and scientific advancements are best delivered by governments. And it should make the case that we – the people – should embrace faith in technological progress that is rooted in public investment.In other words, the left should be the real techno-optimists. But instead, in recent years, there has been a growing skepticism of technology on the contemporary left – from cynicism about space-faring to fear of genetic engineering and opposition to nuclear power.The left should be calling for government intervention to ensure decarbonization of data centers for AI. It should demand that we direct machine-learning research to prioritize the solving of grand scientific challenges such as prediction of protein folding instead of than bad fantasy-art fabrication and plagiarism. But instead, the most popular leftwing tech podcast calls for degrowth of generative AI and data centers due the latter’s carbon intensity.Progressives could be reminding the world of Neil Armstrong’s warning about the privatization of space – while still cheering on SpaceX’s work to develop reusable rocketry, radically reducing the cost of humans and payloads escaping our planet’s gravity well, all the better to deliver the space and planetary science we need to monitor and solve so many ecological challenges.We could be explaining how space colonization, a worthwhile multigenerational, perhaps millennia-long endeavor, will be public sector led or it will not happen, due to the risible likelihood of it being profitable. Musk won’t get to mars without Nasa. But instead the left declares space-faring to be settler-colonialism, oddly equating lifeless rocks with indigenous peoples.Environmentalists and green NGOs should be celebrating research into genetically modified crops that if successful will reduce pesticide use, nitrogen pollution, and land-use change. But instead, anti-GMO campaign groups vandalized an Italian research trial of rice-blast-resistant arborio (risotto) rice this summer, while Greenpeace successfully convinced a Filipino court to overturn approval of commercial cultivation of Golden Rice, a variety modified to combat vitamin A deficiency, which causes blindness and even death in tens of thousands of children annually in Asia.This leftwing technophobia is something of an historic aberration. Traditionally, the left had always been enthusiastic about the potential of technology for liberation, to release us from drudgery and boundlessly expand our degrees of freedom – so long as technology was unfettered from the irrationality of profit and hierarchy and yoked to egalitarian reason. Prometheus plus Spartacus, as mid-century Marxist Hal Draper put it.We sometimes forget that the Communist Manifesto was itself a techno-optimist declaration of intent. It was a critique of capitalism but it was also a celebration of the new technologies, both industrial and social, that this system had set loose.From Karl Marx’s enthusiasm for the Industrial Revolution through to British Labour prime minister Harold Wilson’s call to harness the “white heat” of the Scientific Revolution, the conventional left position was that its programme would enable society to surpass the technological progress of mere capitalism. The point was not to retreat from capitalism, but instead to advance from it. We the people would develop the “forces of production” much more rapidly through conscious, democratic planning (albeit to greater or lesser degrees of such planning, depending on the flavour of leftist) rather than leaving such development to the fetters imposed by the risk-averse, poorly coordinated and unconscious anarchy of the market.@font-face{font-family:Guardian Headline Full;src:url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.woff2) format(“woff2”),url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.woff) format(“woff”),url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.ttf) format(“truetype”);font-weight:300;font-style:normal}@font-face{font-family:Guardian Headline 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      The left should be the real techno-optimists. But instead, in recent years, there has been a growing skepticism of technology on the contemporary left
      Scientific, technological and industrial development would not only be faster, but broader, for the left would share the fruits of development with all humanity as rapidly as economic capacity would allow, rather than limiting their spread to those locations and populations where such production was profitable. A virtuous circle was then supposed to emerge as a result: with ever more humans benefiting from such progress, ever more humans would be able to contribute to science, engineering, medicine and agronomy, resulting in yet more progress. Liberation would beget ever accelerating liberation.It was instead the counter-Enlightenment right – aristocrats, the church, Burkean critics of the French Revolution – who were horrified at how technology and industry constantly revolutionized society, washing away ancient traditions and endlessly transforming social relations. The industrial engineering of the factory and the “social engineering” of democracy were the same thing to the reactionary, anti-modernist mind. The children of the Radical Enlightenment, both liberals and socialists, also made little distinction between social and technological progress, but thought them good, and were intent on carrying out French revolutionary Georges Danton’s commandment: “De l’audace, encore de l’audace, toujours de l’audace!” (“Audacity; yet more audacity; always audacity!”)Today, however, that leftwing optimism and confidence about humanity’s capacity for superior, entwined social, scientific and technological progress – once political economy was thoroughly democratized, has been lost, especially on the environmental left. It has been replaced by a techno-scepticism and cynicism about progress that varies from a soft neo-Luddism through to a more thoroughgoing Malthusian opposition to further economic development, prompted by a fear that we have long since outstripped the carrying capacity of the planet. Many believe industrial modernity was a mistake.(Note that these contemporary neo-Luddites should not be confused with the historical Luddites, the 19th Century stockingers – workers running stocking frame mechanical knitting machines – who engaged in riot and sabotage of automated textile machinery to protest employers’ use of such machines to drive down wages. It was the capitalist socio-economic relations surrounding this technology that the Luddites were protesting, not technology itself. If anything, today’s neo-Luddites should learn from their namesakes and focus less on the machines and more on who owns them.)All of this creeping anti-modernism threatens not merely human development and the expanding freedom that flows from it, but also undermines our ability to adequately respond to a range of existential threats, from climate change to pandemics. We are caught between the capitalist techno-hucksterism of Musk and the Malthusian technophobia of Greenpeace and friends.Thankfully, there is – to coin a phrase – a third way.In place of technophobia, the left’s traditional arguments around the “market alignment problem” still offer a better path toward enhancing human liberation. In place of both market fundamentalist neoliberalism and green-inflected neo-Luddism, the left should be talking once again about conscious design of the economy – and thence which technologies we want to develop and accelerate – through industrial policy, public ownership and other forms of democratic economic planning.As of 2024, we are roughly at the halfway point between the first climate treaty, 1997’s Kyoto Protocol, and the 2050 deadline for net-zero decarbonization of the economy. Yet due to policymakers’ overdependence on market-based mechanisms such as carbon-pricing (and the developing world’s understandable demand for fossil-fueled development), the share of fossil fuels in global energy consumption has barely moved, dropping from 86% to 82%. But industrial policy domestically – building on Bidenomics’ version of the Green New Deal, the Inflation Reduction Act – and a properly egalitarian approach to climate finance and economic development internationally, can turn all this around.Our suite of antibiotics is rapidly failing and so in the absence of new discovery and development of new ones, as well as new diagnostic techniques and vaccines, clinicians warn that we are nearing a collapse of the foundation of antimicrobial protection upon which almost all of modern medicine depends. But decommodification of pharmaceutical production and, again, internationalism could solve the problem entirely.Similarly, pandemic monitoring and early warning systems require robust public-sector funding, restructuring of intellectual property rights, and even global democracy. All of this is optimized by a more muscular social democracy.@font-face{font-family:Guardian Headline Full;src:url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.woff2) format(“woff2”),url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.woff) format(“woff”),url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-Light.ttf) format(“truetype”);font-weight:300;font-style:normal}@font-face{font-family:Guardian Headline Full;src:url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-LightItalic.woff2) format(“woff2”),url(https://assets.guim.co.uk/static/frontend/fonts/guardian-headline/noalts-not-hinted/GHGuardianHeadline-LightItalic.woff) 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      There are so many areas where the left should have so much more to say about technology and progress
      Biodiversity loss threatens to undermine ecosystem services that we depend upon, but precision agriculture, new genetic techniques and “lab meat” can radically reduce humanity’s land-footprint, so long as there is strong state intervention to de-risk these new technologies.In order to overcome less well known but still profound risks from space debris and near-Earth asteroids, we need not cynicism about space, but a revival of space as primarily a public-sector enterprise and the sort of internationalism and global democracy that the left favours.But a left approach to technology is not just about avoiding harm, but about grand ambition. Getting to Mars and beyond, spreading life throughout the cosmos, is a gargantuan multi-generational endeavour, of the level of audacity that Danton commanded. Markets will never get us there if it isn’t profitable enough – and it is unlikely to be so.Artificial intelligence has already solved the hard problem of protein-folding, and soon it could radically enhance medical diagnosis, accelerate materials discovery, and reduce mineral exploration costs, and maybe even predict earthquakes, but much of this will require humans working alongside AI rather than AI replacing humans – meaning an increased cost over either humans or computers alone, which will thus tend to be far less attractive to capital. And so AI thus far appears to be primarily directed at much more profitable but far less freedom-enhancing endeavours such as enterprise software, theft from artists and musicians, and ever more panoptical state surveillance.To steal a phrase from artificial intelligence discourse, the market has an “alignment problem”. It is an algorithm independent of human control. And so it could be said that the techno-libertarians want to liberate themselves from all things that unconsciously dominate humanity – except for markets.There are so many areas where the left should have so much more to say about technology and progress, whether the challenges we face are existential threats or how to achieve the most soaring of ambitions.Neither Silicon Valley tech hucksters nor eco-austerity technophobes are up to the task.

      Leigh Phillips is a science writer and a political journalist More