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      Capsized Boat Near Jacksonville, Fla., Leaves 1 Dead and 3 Missing

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      One adult and two children are missing, and four others were rescued on the St. Johns River near Jacksonville, Fla. They were on the water to take pictures of the sunset, an official said.One person died and three others were missing, including two children, after a small boat capsized on a river near Jacksonville, Fla., on Friday night, the authorities said.The U.S. Coast Guard received reports of an overturned vessel around 7 p.m. near Goat Island, which is north of Jacksonville. No one was wearing life jackets, according to a Coast Guard news release.Officials said that the people on board had set out to take photos of the sunset while on the St. Johns River, which is the longest river in Florida and winds through and around Jacksonville.The marine unit of the Jacksonville Sheriff’s Office rescued four boaters who were perched atop the overturned boat. According to the Jacksonville Fire and Rescue Department, none of the survivors were taken to a hospital.There were four others thought to have been underneath the boat. Divers from the sheriff’s office did not find any people underneath the boat, however.“A Coast Guard Station Mayport rescue surface swimmer attempted to contact the people reportedly underneath the vessel but received no responses,” according to the news release.A crew from the sheriff’s office discovered a person in the water who was dead, said Capt. Eric Prosswimmer, a spokesman for the fire department.It was not immediately clear what caused the boat to capsize. Additional details about those on board were not released.“It’s an 18-foot watercraft boat — a pleasure craft so to speak,” Captain Prosswimmer told reporters on Friday night. “We have recovered the boat, and it was flipped. We flipped it back over, and it was towed back to the dock.”Crews from the Coast Guard, Jacksonville Fire and Rescue Department, the sheriff’s office and the Florida Fish and Wildlife Conservation Commission were engaged in the search. Two helicopters were also deployed in the search.The weather was calm in Jacksonville on Friday evening, with a light breeze and passing clouds. More

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      Drugs Have Uses We Can’t Imagine. He’s Using A.I. to Find Them.

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      A little over a year ago, Joseph Coates was told there was only one thing left to decide. Did he want to die at home, or in the hospital?Coates, then 37 and living in Renton, Wash., was barely conscious. For months, he had been battling a rare blood disorder called POEMS syndrome, which had left him with numb hands and feet, an enlarged heart and failing kidneys. Every few days, doctors needed to drain liters of fluid from his abdomen. He became too sick to receive a stem cell transplant — one of the only treatments that could have put him into remission.“I gave up,” he said. “I just thought the end was inevitable.”But Coates’s girlfriend, Tara Theobald, wasn’t ready to quit. So she sent an email begging for help to a doctor in Philadelphia named David Fajgenbaum, whom the couple met a year earlier at a rare disease summit.By the next morning, Dr. Fajgenbaum had replied, suggesting an unconventional combination of chemotherapy, immunotherapy and steroids previously untested as a treatment for Coates’s disorder.Within a week, Coates was responding to treatment. In four months, he was healthy enough for a stem cell transplant. Today, he’s in remission.The lifesaving drug regimen wasn’t thought up by the doctor, or any person. It had been spit out by an artificial intelligence model.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Why Did Israel Resume Airstrikes on Gaza? What to Know About the Attacks

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      The deadly airstrikes shattered a period of relative calm and raised the prospect of a return to all-out war.Israeli forces on Tuesday launched the largest and most deadly attacks on Gaza since a cease-fire with Hamas that began roughly two months ago. The barrage killed hundreds of people, according to health authorities in the enclave.As of midday Tuesday, it remained unclear whether the strikes were a brief attempt to force Hamas to compromise in cease-fire talks or the beginning of a new phase in the conflict.Here’s what you need to know:What happened with the latest strikes?Why did Israel resume airstrikes on Gaza?How did cease-fire negotiations break down?How did Hamas respond to the Israeli airstrikes?How many hostages remain in Gaza?What happened with the latest strikes? More

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      Severe Storm Risk Shifts to East Coast

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      Thunderstorms and potentially tornadoes are expected from Central Florida to western Pennsylvania on Sunday, forecasters said.The deadly bombardment of severe storms that spawned tornadoes and dust storms across the Midwest and South is expected to sweep across the East Coast on Sunday. The system, which has killed at least 36 people, is expected to unleash storms that could generate tornadoes across the Mid-Atlantic and the Southeast.The turbulent weather that has caused widespread destruction is part of a huge cross-country system that dropped hail — some as large as baseballs — and produced tornadoes Friday and Saturday that killed at least 23 people.The system also caused wildfires driven by hurricane-force winds, and dust storms that led to crashes that killed at least 13 people in Kansas, Oklahoma and the Texas Panhandle.On Sunday, the threat of tornadoes and thunderstorms is expected to be over in the South and will shift east, though at a level much lower than it was on Saturday.Forecasters said there would be a slight risk of severe storms and tornadoes from Central Florida to western Pennsylvania. However, a higher enhanced risk was in place for western and central Pennsylvania.“I’m not expecting the coverage to be as significant and the storms to be as numerous in terms of the overall severity,” said Rich Otto, a meteorologist with the National Weather Service’s Weather Prediction Center. “But there’s still going to be a risk for tornadoes, large hail and damaging winds.”Mr. Otto said that Mississippi and Alabama, which experienced the highest possible level of tornado risk on Saturday, “should have a relatively tranquil day on Sunday.”Tornadoes across the South and MidwestLocations of tornado sightings or damage reported since Friday morning. More

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      In Mexico, a Grisly Discovery of Piles of Shoes, Ovens and Human Remains

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      The authorities are investigating the discovery of cremation ovens, human remains, piles of shoes and other personal effects at an abandoned ranch outside Guadalajara.A group of volunteers searching for their missing relatives first received a tip last week about a mass grave hidden in western Mexico.When they arrived at an abandoned ranch outside La Estanzuela, a small rural village outside Guadalajara, they discovered three underground cremation ovens, burned human remains, hundreds of bone shards and discarded personal items, along with figurines of Santa Muerte — the Holy Death.The Mexican authorities, who were notified of the grisly discovery, said in several statements that they later found 96 shell casings of various calibers and metal gripping rings at the ranch. By last Friday, the discovery was dominating local newspapers and TV reports, and the search group was referring to the site as an “extermination camp.”It is unclear how many people died on the site, and none of remains have been identified. The authorities have yet to say who operated the camp, what crimes were committed there and for how long. But this week, the Attorney General’s Office took over the investigation at the request of President Claudia Sheinbaum.Photos taken by the authorities and by the volunteer group, Searching Warriors of Jalisco, at the abandoned ranch showed more than 200 shoes piled together and heaps of other personal items: a blue summer dress, a small pink backpack, notebooks, pieces of underwear. The more than 700 personal items were a chilling hint about the number of people who may have died there.In a country seemingly inured to episodes of brutal violence from drug cartels, where clandestine graves emerge every month, the images shocked Mexicans and prompted outraged human rights groups to demand that the government put an end to the violence that has ravaged the nation for years.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      $3.5 Million Settlement in Sacramento Jail Death

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      The fatal overdose of a homeless man at a Sacramento County jail is one of multiple deaths in which staff have been accused of medical neglect.The family of a man who died from an overdose in a Sacramento County jail after being left unattended for hours have agreed to a $3.5 million settlement.That man, David Kent Barefield Sr., 55, was dragged across a garage into the jail last May, not given a medical exam despite being visibly ill, handcuffed in a cart while awaiting booking and only offered medical aid in his final minutes, jail footage shows.Mr. Barefield’s relatives described the neglect in a civil case filed last December against the county’s Sheriff’s Office, its health department and the City of Sacramento police. The settlement was confirmed by the family’s lawyer and by a county spokeswoman; a copy of the document shows it was signed on March 5. The case with the city is still pending.The Sheriff’s Office investigated Mr. Barefield’s death and found that none of its employees violated any law or policy, according to a redacted report that was released to The New York Times and The Desert Sun on Thursday.Mr. Barefield being dragged inside the jail, as captured in surveillance footage.via Sacramento Sheriff Legal AffairsThe details of Mr. Barefield’s last hours are captured in surveillance and body camera video obtained by The Times and The Sun through a records request. The organizations previously reported some of that information, citing accounts from lawyers and medical experts who investigated the death and six others in the county’s jails last year as part of a federal court monitoring program. The court had appointed those monitors in a class-action lawsuit related to broader complaints about medical care in the facilities.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Grieving Covid Losses, Five Years Later

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      <!–> –><!–> [–><!–> –><!–> [–><!–> –><!–> [–><!–> –><!–> [–><!–> –><!–> [–><!–> –> <!–> –><!–> [–><!–> –><!–> [–><!–> –><!–> [–><!–>More than 1.2 million Americans died in the coronavirus pandemic. For their grieving families, the fifth anniversary of the pandemic’s beginning is an aching reminder of what they have lost.–><!–> –><!–> [–><!–> –><!–> [–><!–> –><!–> [–><!–> –><!–> […] More

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      3 People Killed in Medical Helicopter Crash in Mississippi

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      A pilot and two crew members were aboard the helicopter, which was not carrying any patients when it plunged into the woods outside Jackson.All three people working aboard a medical helicopter were killed when it crashed into a densely wooded area outside Jackson, Miss., on Monday while returning from transporting a patient, hospital officials said.Two of the people were crew members who worked for the University of Mississippi Medical Center and the other was a pilot, Dr. LouAnn Woodward, the medical center’s top administrator, said during a news conference. The helicopter was not carrying any patients at the time of the accident, she added.It was not clear what caused the aircraft, which the Federal Aviation Administration identified as a Eurocopter EC-135, to lose control. The F.A.A. said that it and the National Transportation Safety Board would investigate the crash, which occurred around 1:15 p.m.Officials did not release the names of the three people who died. They were based out of Columbus, Miss., and were part of AirCare 3, one of four medical helicopter units operated by the medical center.“The entire medical center family is heartbroken over this,” Dr. Woodward said. “This is the crew that responds to emergencies all across the state, and to see them today to respond to one of their own was just something that you can’t put into words.”Dr. Woodward said that the AirCare helicopters and their crews played an integral role in providing critical care services across Mississippi, and that they had a spotless safety record until the crash on Monday.The crews frequently include nurses and paramedics, according to an information page on the medical center’s website. They are equipped with oxygen, ventilators and other critical care equipment.Dr. Woodward said that the pilot who died worked for Med-Trans, the company that leases the AirCare helicopters to the medical center.The company did not immediately respond to a request for comment on Monday.The crash happened a little more than five weeks after a medical jet crashed in Philadelphia, killing six people aboard the plane and one person on the ground. And it added to a spate of recent aviation accidents. On Jan. 29, an American Airlines regional jet and an Army helicopter collided over the Potomac River in Washington, D.C., leaving no survivors. On Feb. 17, a Delta Air Lines flight trying to land at Toronto Pearson International Airport amid strong winds and drifting snow crashed and flipped over on the tarmac; all 80 people who were aboard that plane survived. More