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    A Blood Test for Alzheimer’s: What to Know

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    The test may make it easier to identify whether people with memory and thinking problems have Alzheimer’s or not.A blood test that can help diagnose Alzheimer’s disease has received clearance from the Food and Drug Administration. This is a step toward a goal of scientists and doctors to one day be able to diagnose a confounding illness with the prick of a finger. But there is still a long way to go.Here is what to know:What is the test, and how should it be used?The test, manufactured by Fujirebio Diagnostics, is intended to be used only by specialists in Alzheimer’s, the F.D.A. said. Its mouthful of a name — Lumipulse G pTau217/ß-Amyloid 1-42 Plasma Ratio — describes what the test measures: levels of two proteins, amyloid and tau, that are hallmarks of Alzheimer’s disease.In people who develop Alzheimer’s, amyloid begins to accumulate and form plaques in the brain more than 20 years before any symptoms of cognitive impairment. Tau accumulates later, forming tangles in the brain, and is much more closely correlated with cognitive decline.Can people who don’t have memory problems take the blood test?No. The F.D.A., and Alzheimer’s experts, emphasized that the blood test should be given only to people who are already experiencing cognitive decline and are ages 55 and older. Moreover, it should not be used on its own to diagnose or to rule out Alzheimer’s.“Other clinical evaluations or additional tests should be used for determining treatment options,” the F.D.A. said in a statement, adding that “the results must be interpreted in conjunction with other patient clinical information.”The current gold standard for diagnosing Alzheimer’s still involves either imaging using PET scans, which are expensive, or spinal taps, which are invasive. The blood test can help flag the presence of the Alzheimer’s-related proteins, and doctors might then order confirmatory testing with one of the other methods.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      F.D.A. Approves Novavax Covid Vaccine With Stricter New Conditions

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      The agency narrowed who can get the shot and added new study requirements that could cost the company tens of millions.The Food and Drug Administration on Friday approved the Novavax Covid-19 vaccine, but only for older adults and for others over age 12 who have at least one medical condition that puts them at high risk from Covid.Scientific advisers to the Centers for Disease Control and Prevention, who typically make decisions on who should get approved shots and when, have been debating whether to recommend Covid shots only to the most vulnerable Americans. The F.D.A.’s decision appeared to render at least part of their discussion moot.The new restriction will sharply limit access to the Novavax vaccine for people under 65 who are in good health. It may leave Americans who do not have underlying conditions at risk if a more virulent version of the coronavirus were to emerge. It could also limit options for people who want the vaccine for a wide array of reasons, including to protect a vulnerable loved one.The vaccine had previously been authorized under emergency use. Covid vaccines developed by Pfizer-BioNTech and Moderna, which are more widely used by Americans, were granted full approval in 2022. However, the companies are working on updated shots for the fall, and the new restrictions on the Novavax shot portend a more restrictive approach from the F.D.A.The F.D.A.’s new restrictions also appeared to reflect the high degree of skepticism about vaccines from Robert F. Kennedy Jr., the health secretary, and the other leaders he has appointed at health agencies.“This is incredibly disappointing,” said Dr. Camille Kotton, an infectious disease physician at Massachusetts General Hospital who cares for immunocompromised patients, and a former adviser to the C.D.C.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Trump Budget Cuts Hobble Antismoking Programs

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      Students at Wyoming East High School in West Virginia’s coal country had different reasons for joining Raze, a state program meant to raise awareness about the health risks of tobacco and e-cigarettes.Cayden Oliver, 17, grew up around generations of people who smoked and vaped, and he wanted to make his own choice. Nathiah Brown, 18, was struggling to quit e-cigarettes and showed up for moral support. Kimberly Mills, 18, wanted to prove that even though she had been a foster child, she would defy the odds.This high school’s program cost West Virginia less than $3,000 a year and was meant to protect teenagers in the state that has the highest vaping rate in their age group. It fell prey to U.S. government health budget cuts that included hundreds of millions of dollars in tobacco control funds that reached far beyond Washington, D.C.At the high school, students pack into stalls in the school restrooms, sneaking puffs between classes. “It’s bad now,” said Logan Stacy, 18, a member of the Raze group. “Imagine what it will be like in two years.”Experts on tobacco control said the Trump administration’s funding cuts would set back a quarter-century of public health efforts that have driven the smoking rate to a record low and saved lives and billions of dollars in health care spending. Still, the Centers for Disease Control and Prevention estimates that nearly 29 million people in the United States continue to smoke.The decimation of antismoking work follows a year of lavish campaign donations by tobacco and e-cigarette companies to President Trump and congressional Republicans.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      5 Places to Turn for Accurate Health Information

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      Changes to federal health websites have raised concerns about their reliability. These independent sources offer an alternative.Soon after President Donald J. Trump took office for his second term, thousands of health websites run by the federal government that kept the public informed about infectious diseases, mental health, vaccines and more were taken offline.Many eventually returned — in large part because a judge ordered the Centers for Disease Control and Prevention to temporarily restore the pages — but some had been altered, with sections on topics such as health equity and teen pregnancy deleted. The changes, along with uncertainty around the future of these sites, has led some public health experts to question whether the websites can still be trusted as the gold standard of trustworthy health information, as they’ve long been regarded.Federal health agencies are already facing a crisis of confidence. When a recent national poll asked respondents how much trust they had in the C.D.C. to make the right health recommendations, more than one-third replied “not much” or “not at all.” Nearly half said the same about the Food and Drug Administration.Experts fear that with less trust in public health institutions, more people seeking medical information might turn to social media, where misinformation is rampant. That has made it all the more valuable for the public to find evidenced-based sources of health information.Here are five websites run by independent organizations that have accurate, easy-to-understand information.1. Vaccine Education CenterOf all the health information on federal websites, medical experts have been increasingly concerned about the availability of accurate vaccine information. Robert F. Kennedy Jr., the nation’s health secretary, has been a longtime critic of vaccines and has spread misinformation about their safety for years.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      RFK Jr. Announces Ban on Food Dyes and Says ‘Sugar Is Poison’

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      Health Secretary Robert F. Kennedy Jr. escalated his war against the food industry on Tuesday, declaring that “sugar is poison.”Mr. Kennedy’s comment came during a highly publicized news conference where he also asserted that he has “an understanding” with major food manufacturers to remove petroleum-based food colorings from their products by 2026.No one from the food industry attended the event, and none have publicly agreed to Mr. Kennedy’s demands, although the International Dairy Foods Association has pledged to eliminate artificial colors in milk cheese and yogurt sold to schools as part of the federal lunch and breakfast programs by the start of the 2026 school year.However, Mr. Kennedy and his advisers said that every major food manufacturer and some fast-food companies have contacted the agency looking for guidance.“Four years from now, we are going to have most of these products off the market, or you will know about them when you go to the grocery store,” Mr. Kennedy said.Mr. Kennedy’s push to get food manufacturers to remove dyes from their products is his first effort at sweeping reform of the food industry, which he has long blamed for creating and marketing ultra-processed foods that he says are making Americans obese and contributing to a host of diseases, including diabetes and heart disease.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Patients Cut Off From Cheaper Obesity Drugs as FDA Halts Sales of Copycats

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      Hundreds of thousands of Americans stand to soon lose their access to cheaper weight-loss drugs, with a federal crackdown on copycat versions threatening to disrupt treatment and raise costs.The Food and Drug Administration has ordered producers and sellers of the less expensive products to wind down operations in the coming weeks now that it has declared there are no longer shortages of the blockbuster drugs Wegovy and Zepbound.Produced through a process of mixing drug ingredients known as compounding, the copycat medications had spawned a booming multi-billion-dollar industry. Patients turned to compounding because their health insurance would not pay for the brand-name drugs and they could buy the compounded versions for less than $200 a month in some cases.Eli Lilly and Novo Nordisk now offer the brand-name drugs for $500 a month in most cases to patients who pay with their own money instead of going through insurance. Until recently, patients sometimes had to pay over $1,300 a month.The F.D.A. ordered compounding for versions of Eli Lilly’s Zepbound to end last month. Small compounders have until April 22 to stop making and selling versions of Novo Nordisk’s Wegovy; large compounders have until May 22.It is not clear how the F.D.A. will enforce these deadlines. The Health and Human Services Department, which oversees the F.D.A., declined to answer questions for this article.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Supreme Court Rules Against Makers of Flavored Vapes Popular With Teens

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      The justices said the Food and Drug Administration had acted lawfully in rejecting applications from makers of flavored liquids used in e-cigarettes.The Supreme Court ruled on Wednesday that the Food and Drug Administration had acted lawfully in rejecting applications from two manufacturers of flavored liquids used in e-cigarettes with names like Jimmy the Juice Man Peachy Strawberry, Signature Series Mom’s Pistachio and Suicide Bunny Mother’s Milk and Cookies.In a unanimous decision written by Justice Samuel A. Alito Jr., the justices upheld an F.D.A. order that prohibited retailers from marketing flavored tobacco products. The court rejected claims that the agency had unfairly switched its requirements during the application process.Justice Alito wrote that the agency’s denials of the applications were “sufficiently consistent” with agency guidance on tobacco regulations. The justices rejected a ruling by the U.S. Court of Appeals for the Fifth Circuit that the agency had acted arbitrarily and capriciously, finding that the F.D.A. had not tried to change the rules in the middle of the approval process.A 2009 law, the Family Smoking Prevention and Tobacco Control Act, requires makers of new tobacco products to obtain authorization from the F.D.A. According to the law, the manufacturers’ applications must demonstrate that their products are “appropriate for the protection of the public health.”The agency has denied many applications under the law, including the two at issue in the case before the justices, saying the flavored liquids presented a “known and substantial risk to youth.”The appeals court ruled last year that the agency had changed the rules in the middle of the application process, accusing it of “regulatory switcheroos” that sent the companies “on a wild-goose chase.” More formally, the court said the agency’s actions had been arbitrary and capricious.In asking the Supreme Court to hear the case, Food and Drug Administration v. Wages and White Lion Investments, No. 23-1038, the agency’s lawyers cited another appeals court that had reached the opposite conclusion. The Fifth Circuit’s decision “has far-reaching consequences for public health and threatens to undermine the Tobacco Control Act’s central objective of ‘ensuring that another generation of Americans does not become addicted to nicotine and tobacco products,’” they wrote, quoting from the other appeals court’s decision. More

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      Why the Right Still Embraces Ivermectin

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      Five years after the pandemic began, interest in the anti-parasitic drug is rising again as right-wing influencers promote it — and spread misinformation about it.Joe Grinsteiner is a gregarious online personality who touts the anti-parasitic drug ivermectin. In a recent Facebook video, he produced a tube of veterinary-grade ivermectin paste — the kind made for deworming horses.He gave the tube a squeeze. Then he licked a slug of the stuff, and gulped.“Yum,” Mr. Grinsteiner said in the Feb. 25 video, one of a number of ivermectin-related posts he has made that have drawn millions of views on Facebook this year. “Actually, that tastes like dead cancer.”Ivermectin, a drug proven to treat certain parasitic diseases, exploded in popularity during the pandemic amid false claims that it could treat or prevent Covid-19. Now — despite a persistent message from federal health officials that its medical benefits are limited — interest in ivermectin is rising again, particularly among American conservatives who are seeing it promoted by right-wing influencers.Mr. Grinsteiner, 54, is a Trump supporter and country music performer who lives in rural Michigan. He has claimed in his videos that ivermectin cured his skin cancer, as well as his wife’s cervical cancer. In a video last month, he said a woman told him her nonverbal autistic child had become verbal after using ivermectin. In a recent phone interview, Mr. Grinsteiner said that he takes a daily dose of ivermectin to maintain his general well-being.There is no evidence to support people taking ivermectin to treat cancer or autism. Yet Mr. Grinsteiner believes that the medical and political establishments just want to keep average people from discovering the healing powers of a relatively affordable drug. We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      What Ivermectin Can (and Can’t) Do

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      Social media posts have promoted the anti-parasitic drug for cancer and Covid. That has doctors alarmed.At least once a week, someone asks Dr. Skyler Johnson if ivermectin can treat their cancer.Patients have asked about the anti-parasitic drug for years, especially during the pandemic. But in recent months, Dr. Johnson, a radiation oncologist at the University of Utah Huntsman Cancer Institute, has fielded more and more questions about the medication.Exaggerated and inaccurate comments about ivermectin have intensified online lately. Google searches for “ivermectin” hit their highest point in January since a Covid wave in 2022. That month, the actor Mel Gibson appeared on the hit podcast “The Joe Rogan Experience” and said that three friends with Stage 4 cancer recovered after taking ivermectin, among other drugs. Researchers said the podcast, which received 10 million views on YouTube alone, fed into a flood of inaccurate claims and misinformation about the drug’s purported health benefits.At the same time, politicians in several states are promoting legislation that would make it easier for people to obtain ivermectin. The governor of Arkansas signed a bill last week that would enable people to buy it without a prescription. Lawmakers in Georgia, Texas, West Virginia, Alabama, Louisiana and Kentucky have filed, or said they plan to file, similar legislation. A wealth of research has shown the drug does not treat Covid. And there is not evidence to support people taking ivermectin to treat cancer.“I understand that people, a lot of times, want to take health into their own hands — they want to figure things out on their own,” said Krissy Lunz Trujillo, an assistant professor of political science at the University of South Carolina who researches health misinformation. “But that might have really serious consequences.”Dr. Johnson worries that people will forgo traditional cancer treatments for a drug that hasn’t been proven to work. He tells patients that there is no rigorous research showing the anti-parasitic drug cures cancer in humans. Still, he has seen some people with early, treatable tumors turn to the drug, and return months later with cancers that have spread to their lymph nodes, bones and brain.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More