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    Patient Dies Weeks After Kidney Transplant From Genetically Modified Pig

    Richard Slayman received the historic procedure in March. The hospital said it had “no indication” his death was related to the transplant.Richard “Rick” Slayman, who made history at age 62 as the first person to receive a kidney from a genetically modified pig, has died about two months after the procedure.Massachusetts General Hospital, where Mr. Slayman had the operation, said in a statement on Saturday that its transplant team was “deeply saddened” at his death. The hospital said it had “no indication that it was the result of his recent transplant.”Mr. Slayman, who was Black, had end-stage kidney disease, a condition that affects more than 800,000 people in the United States, according to the federal government, with disproportionately higher rates among Black people.Surgeons performing the world’s first kidney transplant from a genetically modified pig into a living human in March.Michelle Rose/Massachusetts General Hospital, via Agence France-Presse — Getty ImagesThere are far too few kidneys available for donation. Nearly 90,000 people are on the national waiting list for a kidney.Mr. Slayman, a supervisor for the state transportation department from Weymouth, Mass., had received a human kidney in 2018. When it began to fail in 2023 and he developed congestive heart failure, his doctors suggested he try one from a modified pig.“I saw it not only as a way to help me, but a way to provide hope for the thousands of people who need a transplant to survive,” he said in a hospital news release in March.His surgery, which lasted four hours, was a medical milestone. For decades, proponents of so-called xenotransplantation have proposed replacing ailing human organs with those from animals. The main problem with the approach is the human immune system, which rejects animal tissue as foreign, often leading to serious complications.Recent advances in genetic engineering have allowed researchers to tweak the genes of the animal organs to make them more compatible with their recipients.The pig kidney that was transplanted into Mr. Slayman was engineered by eGenesis, a biotech company based in Cambridge, Mass. Scientists there removed three genes and added seven others to improve compatibility. The company also inactivated retroviruses that pigs carry and could be harmful to humans.“Mr. Slayman was a true pioneer,” eGenesis said in a statement on social media on Saturday. “His courage has helped to forge a path forward for current and future patients suffering from kidney failure.”Mr. Slayman was discharged from the hospital two weeks after his surgery, with “one of the cleanest bills of health I’ve had in a long time,” he said at the time.In a statement published by the hospital, Mr. Slayman’s family said he was kind, quick-witted and “fiercely dedicated to his family, friends and co-workers.” They said they had taken great comfort in knowing that his case had inspired so many people.“Millions of people worldwide have come to know Rick’s story,” they said in the statement. “We felt — and still feel — comforted by the optimism he provided patients desperately waiting for a transplant.” More

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    Witnesses Describe Fear and Deprivation at Besieged Hospital in Gaza

    More than a dozen patients have died as a result of the prolonged Israeli military assault against the Al-Shifa hospital complex, the Gazan authorities say.Seven days after Israel’s military began a raid on the Gaza Strip’s largest hospital, Al-Shifa, a picture of the sustained assault on the complex and its surrounding neighborhood emerges in fragments.Residents nearby described a relentless daily soundtrack of gunshots, airstrikes and explosions. A surgeon spoke of doctors and patients corralled in the emergency ward while Israeli forces took control of the complex outside. A Palestinian teenager who spent four days sheltering in the hospital described the bodies she saw piled up outside the entrance.“They had put the bodies on the side and thrown blankets over them,” said Alaa Abu Al-Kaaf, 18, who said she and her family were at Al-Shifa for days before leaving on Thursday. It was not immediately clear when or how the bodies were brought there.Interviews with other witnesses in the hospital, residents in or near the facility and the Gazan authorities in recent days, as well as with others who have left the complex over the past week, described a situation of fear and deprivation, interrogations and detentions of Palestinian men by Israeli forces, and a persistent lack of food and water.The assault on Al-Shifa, one of Israel’s longest hospital raids of the war in Gaza, began on Monday with tanks, bulldozers and airstrikes. The military said it was aimed at senior officials of Hamas, the armed group that led an attack into southern Israel on Oct. 7. Israel began a war on Gaza in response to that assault, with intense aerial bombardments and a ground offensive.A woman in the Gaza Strip on Thursday after fleeing the Al-Shifa medical complex.Agence France-Presse — Getty ImagesWe are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Gang Violence Pushes Haiti’s Health System to the Brink of Collapse

    Many hospitals in Haiti’s capital have been looted by gangs or abandoned by their staffs amid the violence. Some are open, but too dangerous for people in need of care to reach.Taïna Cenatus, a 29-year-old culinary student in Haiti, lost her balance at school one day this month and toppled over, but it was not until she hit the ground that she realized she had been hit in the face by a stray bullet.It left a small hole in her cheek, just missing her jawbone and teeth.Unlike many Haitians wounded by gunfire in the middle of a vicious gang takeover of the capital, Port-au-Prince, Ms. Cenatus was actually lucky that day — she made it to a clinic. But she is still in pain, her wound swelling, and she cannot get any relief, with more and more hospitals and clinics abandoned by staff or looted by gangs.“My teeth hurt,” she said. “I can feel something is wrong.”A gang assault on Haiti’s capital has left an already weak health care system in tatters.More than half of the medical facilities in Port-au-Prince and a large rural region called Artibonite are closed or not operating at full capacity, experts said, because they are too dangerous to reach or their medicine and other supplies have been stolen.In a country where the United Nations estimates that up to one million people are facing the threat of famine, the unraveling of the medical infrastructure threatens to put thousands more lives at risk.Even in periods of less upheaval, the public health system was already in shambles, but now hospitals run by humanitarian groups and churches that many Haitians depend on are closing one by one.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    A UnitedHealthcare and Mount Sinai Dispute May Force Thousands to Switch Doctors

    As Mount Sinai Hospital and UnitedHealthcare haggle over pay rates, patients may have to pay out-of-network prices if they want to keep their doctors.Stalled contract negotiations between UnitedHealthcare, the health insurance giant, and Mount Sinai Health System, a leading New York City hospital system, are forcing tens of thousands of New Yorkers to switch doctors or risk paying out-of-network prices.The impasse has dragged on for months. Mount Sinai has sought to raise prices significantly, but the insurance company has refused to agree to pay the new proposed rates. As a result, Mount Sinai’s hospitals are now out of network for patients insured by UnitedHealthcare or Oxford, which are subsidiaries of the same company. But the issue is about to become even more urgent for many patients because many Mount Sinai affiliated doctors — in addition to the hospitals themselves — are about to be removed from UnitedHealthcare’s network, starting March 22. That means patients with United who have employer-sponsored or individual plans will be billed out-of-network rates when they see a Mount Sinai affiliated doctor at a doctor’s office.The negotiations have sent many patients scrambling to find new doctors. UnitedHealthcare says about 80,000 Mount Sinai patients are affected.What Happened?The dispute between the insurance giant and the hospital system is a rare instance in which health care contract negotiations have spilled into public view.Mount Sinai sought to negotiate better rates with UnitedHealthcare, demanding that the insurance giant pay the hospital more for doctor visits and hospital stays. United claims Mount Sinai was asking for rates to go up some 58 percent over the next four years.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Overwhelmed by War, Another Gazan Hospital Is Declared ‘Not Functional’

    Conditions at Nasser Hospital in the southern Gaza Strip were described as desperate after Israeli forces raided it in search of Hamas militants.The largest medical facility still managing to function in wartime Gaza is now a hospital in little more than name only, the head of the World Health Organization said on Sunday.After a week of siege by the Israeli military, there are only about 20 critically ill patients left at Nasser Hospital — but even that is too many for it to handle, said Tedros Adhanom Ghebreyesus, the W.H.O. director general.“Nasser hospital in Gaza is not functional anymore,” Dr. Tedros said on social media.Dr. Tedros said on Sunday that some 200 patients remained at the hospital in Khan Younis, in the southern Gaza Strip, and that about 20 of them urgently needed to be transferred elsewhere. “The cost of delays will be paid by patients’ lives,” he said.Israel has justified its military actions at the hospital by saying that Hamas militants have been using it and other medical centers to conceal military activities, and on Sunday it said it had found both weapons and Hamas militants at the Nasser complex.Hamas has repeatedly denied using hospitals as cover.On Thursday, after days of repeated orders for the thousands of civilians taking shelter at the hospital to leave, Israeli forces began staging a raid.Asked about the W.H.O. statement, a spokesman for the Israeli military, Lt. Col. Richard Hecht, said in a briefing that “it’s in our best interest that the hospital keeps functioning.” He said that work was being done to fix a broken generator there and that a temporary generator was in use.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Hundreds Flee One of Gaza’s Last Working Hospitals, Fearing Israeli Attack

    Hundreds of displaced Palestinians fled one of the Gaza Strip’s last functioning hospitals on Wednesday, after the Israeli military ordered them to leave and threatened further action to stop what it said was Hamas activity there.Thousands of Gazans have sheltered at the Nasser Medical Complex in the southern city of Khan Younis for weeks, and many are terrified that Israeli forces will bombard or storm the complex, said Mohammed Abu Lehya, a doctor there. Previous Israeli warnings to evacuate hospitals, including Al-Shifa, the largest in Gaza, have often preceded military raids.Hanin Abu Tiba, 27, an English teacher sheltering at the hospital, described dire conditions inside, with food running out and aid convoys all but unable to deliver supplies. In text messages overnight, she said that she had seen an Israeli military vehicle outside the hospital gate.“I’m terrified to leave the hospital and get shot,” she said. But inside the complex, she said, “the electricity is cutting out, and the water, and the canned food is almost gone. We don’t know what to do.”Dr. Abu Lehya, in a WhatsApp message on Wednesday, called conditions at the hospital “beyond imagination.”The tensions at the hospital played out as Israel carried out extensive airstrikes in southern Lebanon on Wednesday in response to a deadly rocket attack on northern Israel. The rocket attack struck a military base near the city of Safed, killing a soldier and wounding eight people, the Israeli authorities said. There was no immediate claim of responsibility, but suspicion quickly fell on Hezbollah, the Lebanese militia allied with Hamas.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Hundreds Flee Nasser Hospital in Gaza After Israel Orders Evacuation

    Hundreds of displaced Palestinians were fleeing a major hospital in the Gaza Strip on Wednesday, according to doctors and videos from the scene, after Israeli forces ordered them to leave and threatened military action to stop what it said was Hamas activity at the hospital.Thousands of Gazans have been sheltering at the Nasser Medical Complex in Khan Younis for weeks, having been forced to flee their homes and other parts of Gaza by Israel’s intense bombardment of the territory and military orders to leave their towns and cities. Hospitals have become places of refuge during the war, even as they have often become a focus of Israel’s military offensive.Inside Nasser, which is one of the last functioning hospitals in Gaza, there was terror that Israeli forces would bombard or storm the complex, said Mohammed Abu Lehya, a doctor there. Previous Israeli warnings to evacuate hospitals, including Al-Shifa, the largest in Gaza, have often preceded military raids on the facilities.“The situation is very difficult, difficult, difficult, difficult,” Dr. Abu Lehya said in a WhatsApp message Wednesday morning. “It’s beyond the imagination or description.”An injured person arriving at Nasser Medical Complex in Khan Younis in December. The hospital is one of the last functioning medical facilities in the Gaza Strip.Yousef Masoud for The New York TimesA video shared on social media on Wednesday and verified by The New York Times shows crowds of people carrying belongings and bedding leaving the hospital as explosions are heard in the background. The Israeli military called for those sheltering to evacuate but said it had not called on patients and medical staff to leave the hospital.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    A Tunnel Offers Clues to How Hamas Uses Gaza’s Hospitals

    Gaza’s hospitals have emerged as a focal point in Israel’s war with Hamas, with each side citing how the other has pulled the facilities into the conflict as proof of the enemy’s disregard for the safety of civilians. In four months of war, Israeli troops have entered several hospitals, including the Qatari Hospital, Kamal Adwan […] More