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    Scientists Describe Rare Syndrome Following Covid Vaccinations

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    In a small study, patients with the syndrome were more likely to experience reactivation of Epstein-Barr virus and high levels of a coronavirus protein.The Covid-19 vaccines were powerfully protective, preventing millions of deaths. But in a small number of people, the shots may have led to a constellation of side effects that includes fatigue, exercise intolerance, brain fog, tinnitus and dizziness, together referred to as “post-vaccination syndrome,” according to a small new study.Some people with this syndrome appear to show distinct biological changes, the research found — among them differences in immune cells, reawakening of a dormant virus called Epstein-Barr, and the persistence of a coronavirus protein in their blood.The study was posted online Wednesday and has not yet been published in a scientific journal. “I want to emphasize that this is still a work in progress,” said Akiko Iwasaki, an immunologist at Yale University who led the work.“It’s not like this study determined what’s making people sick,” she said, “but it’s the first kind of glimpse at what may be going on within these people.”Independent experts noted that the findings were not conclusive on their own. Yet the results, from a scientific team known for rigorous work, suggest that post-vaccination syndrome deserves further scrutiny, they said.“One of the most important things is that we get some attention to really shine a light on this and try to understand exactly what it is,” said John Wherry, director of the Institute for Immunology at the University of Pennsylvania. (Dr. Wherry has previously collaborated with Dr. Iwasaki’s team, but did not participate in this work.)We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Why Do Mental Health Conditions Lead to More Severe Covid?

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      People with psychiatric conditions are more likely to be hospitalized or die of the virus. Scientists have ideas about why that might be the case.It’s been clear since the early days of the pandemic: People with mental illness are more likely to have severe outcomes from Covid. Compared to the general population, they’re at higher risk of being hospitalized, developing long Covid or dying from an infection.That fact puts mental illness on the same list as better-known Covid risk factors like cardiovascular issues, chronic kidney disease and asthma.When it comes to Covid risk, mental illness “shouldn’t be treated differently than you treat diabetes or heart disease or cancer,” said Dr. Ziyad Al-Aly, the chief of research and development at the Veterans Affairs St. Louis Healthcare System.Scientists now have a better understanding of who is vulnerable. While research has linked a wide range of mental illnesses to worse Covid outcomes, experts generally believe that the risk is greatest for people with severe or unmanaged mental health conditions — suggesting that someone with schizophrenia, for example, is more likely to get sicker from Covid than someone receiving treatment for anxiety. They also have several hypotheses about why mental illness might make people more susceptible.The Strain of StressMany mental health conditions can lead to chronically high stress levels. And stress sabotages the immune system, flooding the body with hormones like cortisol and adrenaline. Those hormones make it harder to produce certain immune cells that are crucial for fighting off illnesses.“The whole system is not designed to be constantly activated,” said Andrea Lynne Roberts, a researcher at Harvard University who has studied the effects of mental health conditions on Covid outcomes. That’s why people with mental illness may be more vulnerable to viral infections in general, from the common cold to Covid.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      A Summer Guide to Covid Testing, Symptoms and Treatment

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      Experts say cases could rise in the coming weeks. Here’s what to know about symptoms, testing and treatment.As the so-called “FLiRT” variants of the coronavirus continue to gain traction, doctors and researchers are bracing for a potential rise in cases this summer. KP.2, one of these variants, now accounts for 28.5 percent of cases, and data from the Centers for Disease Control and Prevention shows a small increase in Covid-related emergency room visits and positive tests.Here’s what to know about symptoms, testing and treatment if you do fall ill:Symptoms to watch out forThere’s no evidence that symptoms of the FLiRT variants and other recent strains are any different, said Aubree Gordon, an infectious disease epidemiologist at the University of Michigan.The symptoms still include sneezing, congestion, headaches, sore muscles, nausea or vomiting. Many people also report exhaustion and a general “blah” feeling.In general, the more immunity you’ve built up from vaccination or past infections, the milder your next bout with the virus is likely to be. (Though it’s possible to experience more intense symptoms with a new infection than you’ve had in past Covid cases.)The symptoms of Covid can look similar to those caused by allergies or other infections. The best way to tell the difference is to test.When (and how) to testIn an ideal world, experts said, people would take a Covid test as soon as they develop symptoms or learn they were exposed, and then test again a day or two later. But if you only have a limited number of at-home rapid tests, there are a few ways to maximize their usefulness: Test immediately if you have a fever and a cough, said Dr. Davey Smith, an infectious disease specialist at the University of California, San Diego.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More