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    Pfizer Nears Deal to Provide More Vaccine Doses

    #masthead-section-label, #masthead-bar-one { display: none }Covid-19 VaccinesVaccine QuestionsDoses Per StateAfter Your VaccineHow the Moderna Vaccine WorksWhy You’ll Still Need a MaskAdvertisementContinue reading the main storySupported byContinue reading the main storyPfizer Nears Deal With Trump Administration to Provide More Vaccine DosesThe company could provide at least tens of millions of additional doses of a coronavirus vaccine under an agreement that would give it better access to the supplies it needs to expand manufacturing.A health worker receiving the Pfizer vaccine in Arlington, Va., on Wednesday. The Trump administration is nearing a deal with Pfizer to provide tens of millions of additional doses in the second quarter of next year, helping to address a looming shortage.Credit…Michael A. McCoy for The New York TimesSharon LaFraniere and Dec. 22, 2020Updated 6:17 p.m. ETThe Trump administration and Pfizer are close to a deal under which the pharmaceutical company would bolster supply of its coronavirus vaccine for the United States by at least tens of millions of doses next year in exchange for a government directive giving it better access to manufacturing supplies, people familiar with the discussions said.An agreement, which could be announced as early as Wednesday, would help the United States at least partly offset a looming vaccine shortage that could leave as many as 110 million adult Americans uncovered in the first half of 2021.So far, only two pharmaceutical companies — Pfizer and Moderna — have won federal authorization for emergency distribution of Covid-19 vaccines, and most of what they are capable of producing for the next six months has already been allocated through contracts with the United States and other governments.In the negotiations, the government is asking for 100 million additional doses from Pfizer from April through June. The company has signaled that it should be able to produce at least 70 million, and perhaps more, if it can get more access to supplies and raw materials.To help Pfizer, the deal calls for the government to invoke the Defense Production Act to give the company better access to roughly nine specialized products it needs to make the vaccine. One person familiar with the list said it included lipids, the oily molecules in which the genetic material that is used in both the Moderna and Pfizer vaccines is encased.Pfizer first started asking for the government’s help in obtaining supplies as early as September and has been unhappy about the lack of response, according to documents reviewed by The New York Times.Moderna and other companies that worked more closely than Pfizer with the administration through its Operation Warp Speed to develop their vaccines already receive favored treatment from suppliers, putting Pfizer at a disadvantage. That includes two companies — Sanofi and Novavax — that have yet to begin large-scale clinical trials in the United States.Pfizer and the administration have been negotiating for more doses from Pfizer for more than a month. But a host of other issues have stood in the way of a deal, including Pfizer’s commitments to other nations that moved faster than the United States to lock in a big supply, according to people familiar with the situation.Pfizer already has a federal contract, signed in July, to deliver 100 million doses of its vaccine by the end of March. Moderna has the same agreement, and has also pledged to sell the government 100 million more doses in the second quarter of the year, from the start of April to the end of June.Because the Pfizer and the Moderna vaccine both require two doses, that supply would cover only 150 million Americans out of the roughly 260 million who are eligible at the moment to be vaccinated. (Moderna’s vaccine is now restricted to those 18 and over, and Pfizer’s is limited to those 16 and over.)If Pfizer provides another 100 million doses, that would leave about 60 million eligible Americans uncovered in the first half of the year. Other producers could also cover the shortfall should their vaccines prove successful.It is not clear how many more doses Pfizer can quickly produce even if the administration uses the Defense Production Act to clear away supply obstacles. One person familiar with the situation said the firm may only be able to deliver 70 million by the end of June, even with better access to supplies. Had the government agreed to prioritize its supply needs earlier, one person familiar with Pfizer’s situation said, the company might be better positioned now to fully meet the demands. Documents reviewed by The Times showed that Pfizer officials began asking Gen. Gustave F. Perna, the chief operating officer of Operation Warp Speed, in September for help with supplies and brought up the issue repeatedly in weekly meetings.A senior Trump administration official said the government was unwilling to intervene because Pfizer refused to promise that it would use those materials to produce vaccines solely for Americans..css-fk3g7a{font-family:nyt-franklin,helvetica,arial,sans-serif;font-weight:700;font-size:0.875rem;line-height:1.125rem;color:#121212 !important;}@media (min-width:740px){.css-fk3g7a{font-size:0.9375rem;line-height:1.25rem;}}.css-1sjr751{-webkit-text-decoration:none;text-decoration:none;}.css-1sjr751 a:hover{border-bottom:1px solid #dcdcdc;}.css-rqynmc{font-family:nyt-franklin,helvetica,arial,sans-serif;font-size:0.9375rem;line-height:1.25rem;color:#333;margin-bottom:0.78125rem;}@media (min-width:740px){.css-rqynmc{font-size:1.0625rem;line-height:1.5rem;margin-bottom:0.9375rem;}}.css-rqynmc strong{font-weight:600;}.css-rqynmc em{font-style:italic;}.css-zs9392{margin:10px auto 5px;font-family:nyt-franklin,helvetica,arial,sans-serif;font-weight:700;font-size:1.125rem;line-height:1.3125rem;color:#121212;}@media (min-width:740px){.css-zs9392{font-size:1.25rem;line-height:1.4375rem;}}#NYT_BELOW_MAIN_CONTENT_REGION .css-zs9392{font-family:nyt-cheltenham,georgia,’times new roman’,times,serif;font-weight:700;font-size:1.375rem;line-height:1.75rem;margin-bottom:20px;}@media (min-width:740px){#NYT_BELOW_MAIN_CONTENT_REGION .css-zs9392{font-size:1.5rem;line-height:1.875rem;}}.css-121grtr{margin:0 auto 10px;}.css-16ed7iq{width:100%;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;-webkit-box-pack:center;-webkit-justify-content:center;-ms-flex-pack:center;justify-content:center;padding:10px 0;background-color:white;}.css-pmm6ed{display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;}.css-pmm6ed > :not(:first-child){margin-left:5px;}.css-5gimkt{font-family:nyt-franklin,helvetica,arial,sans-serif;font-size:0.8125rem;font-weight:700;-webkit-letter-spacing:0.03em;-moz-letter-spacing:0.03em;-ms-letter-spacing:0.03em;letter-spacing:0.03em;text-transform:uppercase;color:#333;}.css-5gimkt:after{content:’Collapse’;}.css-rdoyk0{-webkit-transition:all 0.5s ease;transition:all 0.5s ease;-webkit-transform:rotate(180deg);-ms-transform:rotate(180deg);transform:rotate(180deg);}.css-eb027h{max-height:5000px;-webkit-transition:max-height 0.5s ease;transition:max-height 0.5s ease;}.css-6mllg9{-webkit-transition:all 0.5s ease;transition:all 0.5s ease;position:relative;opacity:0;}.css-6mllg9:before{content:”;background-image:linear-gradient(180deg,transparent,#ffffff);background-image:-webkit-linear-gradient(270deg,rgba(255,255,255,0),#ffffff);height:80px;width:100%;position:absolute;bottom:0px;pointer-events:none;}#masthead-bar-one{display:none;}#masthead-bar-one{display:none;}.css-qmg6q8{background-color:white;margin:1.5rem auto 1.9rem;max-width:600px;}#NYT_BELOW_MAIN_CONTENT_REGION .css-qmg6q8{padding:0;width:calc(100% – 40px);max-width:600px;margin-right:auto;margin-left:auto;}.css-qmg6q8 strong{font-weight:700;}.css-qmg6q8 em{font-style:italic;}@media (min-width:740px){.css-qmg6q8{margin:40px auto;}}.css-qmg6q8:focus{outline:1px solid #e2e2e2;}.css-qmg6q8 a{color:#326891;-webkit-text-decoration:none;text-decoration:none;border-bottom:1px solid #ccd9e3;}.css-qmg6q8 a:visited{color:#333;-webkit-text-decoration:none;text-decoration:none;border-bottom:1px solid #ddd;}.css-qmg6q8 a:hover{border-bottom:none;}.css-qmg6q8[data-truncated] .css-rdoyk0{-webkit-transform:rotate(0deg);-ms-transform:rotate(0deg);transform:rotate(0deg);}.css-qmg6q8[data-truncated] .css-eb027h{max-height:300px;overflow:hidden;-webkit-transition:none;transition:none;}.css-qmg6q8[data-truncated] .css-5gimkt:after{content:’See more’;}.css-qmg6q8[data-truncated] .css-6mllg9{opacity:1;}.css-11uwurf{border:1px solid #e2e2e2;padding:15px;border-radius:0;margin:0 auto;overflow:hidden;}@media (min-width:600px){.css-11uwurf{padding:20px;}}#NYT_BELOW_MAIN_CONTENT_REGION .css-11uwurf{border-top:1px solid #121212;border-bottom:none;}Covid-19 Vaccines ›Answers to Your Vaccine QuestionsWith distribution of a coronavirus vaccine beginning in the U.S., here are answers to some questions you may be wondering about:If I live in the U.S., when can I get the vaccine? While the exact order of vaccine recipients may vary by state, most will likely put medical workers and residents of long-term care facilities first. If you want to understand how this decision is getting made, this article will help.When can I return to normal life after being vaccinated? Life will return to normal only when society as a whole gains enough protection against the coronavirus. Once countries authorize a vaccine, they’ll only be able to vaccinate a few percent of their citizens at most in the first couple months. The unvaccinated majority will still remain vulnerable to getting infected. A growing number of coronavirus vaccines are showing robust protection against becoming sick. But it’s also possible for people to spread the virus without even knowing they’re infected because they experience only mild symptoms or none at all. Scientists don’t yet know if the vaccines also block the transmission of the coronavirus. So for the time being, even vaccinated people will need to wear masks, avoid indoor crowds, and so on. Once enough people get vaccinated, it will become very difficult for the coronavirus to find vulnerable people to infect. Depending on how quickly we as a society achieve that goal, life might start approaching something like normal by the fall 2021.If I’ve been vaccinated, do I still need to wear a mask? Yes, but not forever. Here’s why. The coronavirus vaccines are injected deep into the muscles and stimulate the immune system to produce antibodies. This appears to be enough protection to keep the vaccinated person from getting ill. But what’s not clear is whether it’s possible for the virus to bloom in the nose — and be sneezed or breathed out to infect others — even as antibodies elsewhere in the body have mobilized to prevent the vaccinated person from getting sick. The vaccine clinical trials were designed to determine whether vaccinated people are protected from illness — not to find out whether they could still spread the coronavirus. Based on studies of flu vaccine and even patients infected with Covid-19, researchers have reason to be hopeful that vaccinated people won’t spread the virus, but more research is needed. In the meantime, everyone — even vaccinated people — will need to think of themselves as possible silent spreaders and keep wearing a mask. Read more here.Will it hurt? What are the side effects? The Pfizer and BioNTech vaccine is delivered as a shot in the arm, like other typical vaccines. The injection into your arm won’t feel different than any other vaccine, but the rate of short-lived side effects does appear higher than a flu shot. Tens of thousands of people have already received the vaccines, and none of them have reported any serious health problems. The side effects, which can resemble the symptoms of Covid-19, last about a day and appear more likely after the second dose. Early reports from vaccine trials suggest some people might need to take a day off from work because they feel lousy after receiving the second dose. In the Pfizer study, about half developed fatigue. Other side effects occurred in at least 25 to 33 percent of patients, sometimes more, including headaches, chills and muscle pain. While these experiences aren’t pleasant, they are a good sign that your own immune system is mounting a potent response to the vaccine that will provide long-lasting immunity.Will mRNA vaccines change my genes? No. The vaccines from Moderna and Pfizer use a genetic molecule to prime the immune system. That molecule, known as mRNA, is eventually destroyed by the body. The mRNA is packaged in an oily bubble that can fuse to a cell, allowing the molecule to slip in. The cell uses the mRNA to make proteins from the coronavirus, which can stimulate the immune system. At any moment, each of our cells may contain hundreds of thousands of mRNA molecules, which they produce in order to make proteins of their own. Once those proteins are made, our cells then shred the mRNA with special enzymes. The mRNA molecules our cells make can only survive a matter of minutes. The mRNA in vaccines is engineered to withstand the cell’s enzymes a bit longer, so that the cells can make extra virus proteins and prompt a stronger immune response. But the mRNA can only last for a few days at most before they are destroyed.“It’s our obligation under that type of priority rating to make sure that assets are used only for U.S. sales or production,” the official said, “and they weren’t willing to do that.”People knowledgeable about the talks said General Perna had raised a different concern with Pfizer, saying the government wanted to protect its investment in the other companies under Warp Speed’s umbrella, so it did not want to grant Pfizer the same priority with supplies.According to a report last month by the Government Accountability Office, the Defense Production Act gives the federal government vast authority over private companies, including the power to prevent supplies from being diverted to a different purpose or products from being sold overseas. The administration has granted the kind of status that Pfizer has been seeking to multiple contractors for medical supplies since the pandemic began, including companies that produce ventilators and N-95 respirators, the report states.Because the Pfizer vaccine, developed with the German company BioNTech, is one of only two that the Food and Drug Administration has approved for emergency use, the company has had leverage in negotiating the new contract.That advantage could erode if other vaccines are authorized. A third firm, Johnson & Johnson, is expected to announce results from its clinical trials next month. A fourth, AstraZeneca, has announced some interim results, but it has yet to fully enroll its trial in the United States.With infections, hospitalizations and deaths surging to record levels from a pandemic that has already killed more than 320,000 Americans, the pressure on Pfizer and the government to come to terms is growing.“The last thing we want is for this to turn acrimonious,” said Dr. Walid F. Gellad, who leads the Center for Pharmaceutical Policy and Prescribing at the University of Pittsburgh. “This kind of corrosive back-and-forth is not helping the public feel any better about what’s going to happen in the future.”Pfizer’s relationship with the administration has been tense for months. After he lost the election in November, President Trump accused Pfizer of deliberately slow-walking federal approval of its vaccine to hurt him politically.Alex M. Azar II, the secretary of health and human services, and his aides have complained that Pfizer has kept the government at arm’s length, has faced production problems and has sometimes been uncooperative in negotiations.Another snag in the relationship surfaced Friday when a European official released on Twitter — and then quickly deleted — a price list that showing that vaccine shipments to the U.S. government cost a third more per dose than shipments to European customers.Pfizer completed a deal last month to sell the European Union 200 million doses at a cost of $14.50 each. The contract signed by the Trump administration with Pfizer in July for the original 100 million doses put the price at $19.50.It is unclear how much the United States would pay if Pfizer and the federal government struck a new deal. In a statement, Pfizer said only that the European Union’s order was its largest to date, and that Pfizer and BioNTech “are using a tiered pricing formula based on volume and delivery dates.” It declined to disclose further details of the agreement.Pfizer executives have been frustrated because, according to people familiar with the negotiations, they repeatedly urged the federal government this summer and fall to lock in more doses early, before other nations snapped them up. Administration officials declined, later saying that Pfizer refused to commit to specific dates when it would deliver them.The pharmaceutical firm has struggled to navigate the politics of the situation. Pfizer’s chief executive, Dr. Albert Bourla, repeatedly suggested that the firm would know if its vaccine worked by October. Mr. Trump, who saw a vaccine breakthrough as crucial to his re-election chances, initially praised Dr. Bourla as a “great guy” — then blamed the firm for his loss when the results were released after Election Day.At the same time, the president and his top aides have claimed credit for Pfizer’s success, even though, unlike the other five vaccine makers in the Operation Warp Speed program, Pfizer did not take federal subsidies for the vaccine development or manufacturing, assuming all of the risk itself.Pfizer is insisting that in order to bolster production, the Trump administration must direct suppliers to prioritize the company’s purchases of raw materials.Credit…Benjamin Rasmussen for The New York TimesPfizer has also vacillated in describing its relationship with the federal government. A top Pfizer official at one point stated that “we were never part of Operation Warp Speed,” then the company backtracked and acknowledged the firm was.Mr. Azar alluded to the friction with Pfizer in an interview last week with CNBC, saying the federal government was willing to help Pfizer manufacture more “if they are willing to take our help.” He added, “I do wish we would just stop talking about this Pfizer thing.”He denied that there was any threat of a vaccine shortage, saying the government had commitments for three times as many doses as it has now ordered for the first half of next year. Mr. Azar’s total appears to include either doses of vaccines that have not yet been shown to work or doses described in contract options that are not set in stone and include no firm date of delivery, or both.AdvertisementContinue reading the main story More

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    Trump Claims Credit for Vaccines. Some of His Backers Don’t Want to Take Them.

    #masthead-section-label, #masthead-bar-one { display: none }Covid-19 VaccinesVaccine QuestionsDoses Per StateHow the Moderna Vaccine WorksWhy You’ll Still Need a MaskPost-Vaccine OutlookAdvertisementContinue reading the main storySupported byContinue reading the main storyTrump Claims Credit for Vaccines. Some of His Backers Don’t Want to Take Them.A deep distrust of the government is fueling vaccine hesitancy among Republicans, who are more likely than Democrats to resist being inoculated against Covid-19.A pharmacist preparing a dose of the Pfizer vaccine for the coronavirus on Wednesday. The “anti-vaxxer movement” is not new, and it typically cuts across political parties. But partisanship plays a major role in how people view the coronavirus vaccine.Credit…Michael A. McCoy for The New York TimesDec. 18, 2020Updated 9:43 p.m. ETWASHINGTON — Elizabeth Graves, an ardent supporter of President Trump, is not opposed to vaccines. She said she had taken flu shots and pneumonia shots and, having just turned 50, was interested in being vaccinated against shingles.But Ms. Graves, a legal transcriptionist in Starkville, Miss., said she would not be taking a coronavirus vaccine — and the sight of Vice President Mike Pence rolling up his sleeve to get vaccinated on live television on Friday, she added, would not change her mind.Lawrence Palmer, 51, a field service engineer in Boiling Springs, Pa., and Brandon Lofgren, 25, who works in his family’s trucking and construction business in rural Wisconsin, said they felt the same way. All are fans of Mr. Trump, and echoed Ms. Graves, who said she was “suspicious” of government and that Mr. Pence’s vaccination “doesn’t mean a thing to me.”It is a paradox of the pandemic: Helping speed the development of a coronavirus vaccine may be one of Mr. Trump’s proudest accomplishments, but at least in the early stages of the vaccine rollout, there is evidence that a substantial number of his supporters say they do not want to get it.Until the past week, their objections were largely hypothetical. But with a second vaccine about to become available in the United States — the Food and Drug Administration on Friday authorized emergency use of the vaccine developed by Moderna, a week after the version developed by Pfizer and BioNTech won the same approval — more people will confront the choice of getting inoculated or not. The authorization will clear the way for the shipment of 5.9 million doses over the weekend and tens of millions more in coming months, greatly expanding the reach of the vaccination campaign as the nation grapples with the uncontrolled spread of the disease.For the most part, public opinion has been swinging in favor of vaccination. Seventy-one percent of Americans are willing to be vaccinated, up from 63 percent in September, according to a survey released this week by the Kaiser Family Foundation.Still, the survey found that Republicans were the most likely to be hesitant, with 42 percent saying they would probably not or definitely not be vaccinated, as compared with 12 percent of Democrats.Experts say that vaccine hesitancy may diminish over time if people see friends and relatives getting vaccinated without incident. Sheri Simms, 62, a retired businesswoman in Northeast Texas who describes herself as a “moderate conservative” supporter of the president, said that while she did not intend to get vaccinated now, that could change.“As more information comes out, and things appear to work better, then I will weigh the risks of the vaccine against the risk of the coronavirus and make a judgment,” she said.The “anti-vaxxer movement” is not new, and it typically cuts across political parties. But the coronavirus vaccine, developed against the backdrop of a bitterly fought presidential election and championed by an especially polarizing figure in Mr. Trump, has become especially associated with partisanship.During the campaign, while Mr. Trump was promising a vaccine by Election Day, some Democrats expressed concern about whether safety would be sacrificed in the rush to deliver a vaccine in time to help the president at the polls.Political leaders in both parties worked on Friday to dispel concerns about the vaccine.Mr. Pence, who took the Pfizer vaccine on Friday in a ceremony at the Eisenhower Executive Office Building in Washington, was not the only prominent public official to get vaccinated. On Capitol Hill, congressional leaders including Speaker Nancy Pelosi, a Democrat, and Senator Mitch McConnell, the Republican leader, were also inoculated against Covid-19. President-elect Joseph R. Biden Jr. and his wife, Jill Biden, are to be vaccinated on Monday..css-fk3g7a{font-family:nyt-franklin,helvetica,arial,sans-serif;font-weight:700;font-size:0.875rem;line-height:1.125rem;color:#121212 !important;}@media (min-width:740px){.css-fk3g7a{font-size:0.9375rem;line-height:1.25rem;}}.css-1sjr751{-webkit-text-decoration:none;text-decoration:none;}.css-1sjr751 a:hover{border-bottom:1px solid #dcdcdc;}.css-rqynmc{font-family:nyt-franklin,helvetica,arial,sans-serif;font-size:0.9375rem;line-height:1.25rem;color:#333;margin-bottom:0.78125rem;}@media (min-width:740px){.css-rqynmc{font-size:1.0625rem;line-height:1.5rem;margin-bottom:0.9375rem;}}.css-rqynmc strong{font-weight:600;}.css-rqynmc em{font-style:italic;}.css-zs9392{margin:10px auto 5px;font-family:nyt-franklin,helvetica,arial,sans-serif;font-weight:700;font-size:1.125rem;line-height:1.3125rem;color:#121212;}@media (min-width:740px){.css-zs9392{font-size:1.25rem;line-height:1.4375rem;}}#NYT_BELOW_MAIN_CONTENT_REGION .css-zs9392{font-family:nyt-cheltenham,georgia,’times new roman’,times,serif;font-weight:700;font-size:1.375rem;line-height:1.75rem;margin-bottom:20px;}@media (min-width:740px){#NYT_BELOW_MAIN_CONTENT_REGION .css-zs9392{font-size:1.5rem;line-height:1.875rem;}}.css-121grtr{margin:0 auto 10px;}.css-16ed7iq{width:100%;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;-webkit-box-pack:center;-webkit-justify-content:center;-ms-flex-pack:center;justify-content:center;padding:10px 0;background-color:white;}.css-pmm6ed{display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;}.css-pmm6ed > :not(:first-child){margin-left:5px;}.css-5gimkt{font-family:nyt-franklin,helvetica,arial,sans-serif;font-size:0.8125rem;font-weight:700;-webkit-letter-spacing:0.03em;-moz-letter-spacing:0.03em;-ms-letter-spacing:0.03em;letter-spacing:0.03em;text-transform:uppercase;color:#333;}.css-5gimkt:after{content:’Collapse’;}.css-rdoyk0{-webkit-transition:all 0.5s ease;transition:all 0.5s ease;-webkit-transform:rotate(180deg);-ms-transform:rotate(180deg);transform:rotate(180deg);}.css-eb027h{max-height:5000px;-webkit-transition:max-height 0.5s ease;transition:max-height 0.5s ease;}.css-6mllg9{-webkit-transition:all 0.5s ease;transition:all 0.5s ease;position:relative;opacity:0;}.css-6mllg9:before{content:”;background-image:linear-gradient(180deg,transparent,#ffffff);background-image:-webkit-linear-gradient(270deg,rgba(255,255,255,0),#ffffff);height:80px;width:100%;position:absolute;bottom:0px;pointer-events:none;}#masthead-bar-one{display:none;}#masthead-bar-one{display:none;}.css-qmg6q8{background-color:white;margin:1.5rem auto 1.9rem;max-width:600px;}#NYT_BELOW_MAIN_CONTENT_REGION .css-qmg6q8{padding:0;width:calc(100% – 40px);max-width:600px;margin-right:auto;margin-left:auto;}.css-qmg6q8 strong{font-weight:700;}.css-qmg6q8 em{font-style:italic;}@media (min-width:740px){.css-qmg6q8{margin:40px auto;}}.css-qmg6q8:focus{outline:1px solid #e2e2e2;}.css-qmg6q8 a{color:#326891;-webkit-text-decoration:none;text-decoration:none;border-bottom:1px solid #ccd9e3;}.css-qmg6q8 a:visited{color:#333;-webkit-text-decoration:none;text-decoration:none;border-bottom:1px solid #ddd;}.css-qmg6q8 a:hover{border-bottom:none;}.css-qmg6q8[data-truncated] .css-rdoyk0{-webkit-transform:rotate(0deg);-ms-transform:rotate(0deg);transform:rotate(0deg);}.css-qmg6q8[data-truncated] .css-eb027h{max-height:300px;overflow:hidden;-webkit-transition:none;transition:none;}.css-qmg6q8[data-truncated] .css-5gimkt:after{content:’See more’;}.css-qmg6q8[data-truncated] .css-6mllg9{opacity:1;}.css-11uwurf{border:1px solid #e2e2e2;padding:15px;border-radius:0;margin:0 auto;overflow:hidden;}@media (min-width:600px){.css-11uwurf{padding:20px;}}#NYT_BELOW_MAIN_CONTENT_REGION .css-11uwurf{border-top:1px solid #121212;border-bottom:none;}Covid-19 Vaccines ›Answers to Your Vaccine QuestionsWith distribution of a coronavirus vaccine beginning in the U.S., here are answers to some questions you may be wondering about:If I live in the U.S., when can I get the vaccine? While the exact order of vaccine recipients may vary by state, most will likely put medical workers and residents of long-term care facilities first. If you want to understand how this decision is getting made, this article will help.When can I return to normal life after being vaccinated? Life will return to normal only when society as a whole gains enough protection against the coronavirus. Once countries authorize a vaccine, they’ll only be able to vaccinate a few percent of their citizens at most in the first couple months. The unvaccinated majority will still remain vulnerable to getting infected. A growing number of coronavirus vaccines are showing robust protection against becoming sick. But it’s also possible for people to spread the virus without even knowing they’re infected because they experience only mild symptoms or none at all. Scientists don’t yet know if the vaccines also block the transmission of the coronavirus. So for the time being, even vaccinated people will need to wear masks, avoid indoor crowds, and so on. Once enough people get vaccinated, it will become very difficult for the coronavirus to find vulnerable people to infect. Depending on how quickly we as a society achieve that goal, life might start approaching something like normal by the fall 2021.If I’ve been vaccinated, do I still need to wear a mask? Yes, but not forever. Here’s why. The coronavirus vaccines are injected deep into the muscles and stimulate the immune system to produce antibodies. This appears to be enough protection to keep the vaccinated person from getting ill. But what’s not clear is whether it’s possible for the virus to bloom in the nose — and be sneezed or breathed out to infect others — even as antibodies elsewhere in the body have mobilized to prevent the vaccinated person from getting sick. The vaccine clinical trials were designed to determine whether vaccinated people are protected from illness — not to find out whether they could still spread the coronavirus. Based on studies of flu vaccine and even patients infected with Covid-19, researchers have reason to be hopeful that vaccinated people won’t spread the virus, but more research is needed. In the meantime, everyone — even vaccinated people — will need to think of themselves as possible silent spreaders and keep wearing a mask. Read more here.Will it hurt? What are the side effects? The Pfizer and BioNTech vaccine is delivered as a shot in the arm, like other typical vaccines. The injection into your arm won’t feel different than any other vaccine, but the rate of short-lived side effects does appear higher than a flu shot. Tens of thousands of people have already received the vaccines, and none of them have reported any serious health problems. The side effects, which can resemble the symptoms of Covid-19, last about a day and appear more likely after the second dose. Early reports from vaccine trials suggest some people might need to take a day off from work because they feel lousy after receiving the second dose. In the Pfizer study, about half developed fatigue. Other side effects occurred in at least 25 to 33 percent of patients, sometimes more, including headaches, chills and muscle pain. While these experiences aren’t pleasant, they are a good sign that your own immune system is mounting a potent response to the vaccine that will provide long-lasting immunity.Will mRNA vaccines change my genes? No. The vaccines from Moderna and Pfizer use a genetic molecule to prime the immune system. That molecule, known as mRNA, is eventually destroyed by the body. The mRNA is packaged in an oily bubble that can fuse to a cell, allowing the molecule to slip in. The cell uses the mRNA to make proteins from the coronavirus, which can stimulate the immune system. At any moment, each of our cells may contain hundreds of thousands of mRNA molecules, which they produce in order to make proteins of their own. Once those proteins are made, our cells then shred the mRNA with special enzymes. The mRNA molecules our cells make can only survive a matter of minutes. The mRNA in vaccines is engineered to withstand the cell’s enzymes a bit longer, so that the cells can make extra virus proteins and prompt a stronger immune response. But the mRNA can only last for a few days at most before they are destroyed.In any other era, Mr. Pence’s vaccination, administered by a technician from the Walter Reed National Military Medical Center in Bethesda, Md., in images beamed across the country, would have been a moment to bring the nation together. He took the shot in front of a giant blue poster declaring in white block letters: “SAFE and EFFECTIVE.”His wife, Karen Pence, and Surgeon General Jerome Adams were also vaccinated.Vice President Mike Pence received the Pfizer vaccine on Friday in a ceremony at the Eisenhower Executive Office Building in Washington.Credit…Doug Mills/The New York Times“I didn’t feel a thing — well done,” the vice president said afterward, adding that he wanted to “assure the American people that while we cut red tape, we cut no corners.”But Mr. Trump was notably absent. One reason for the partisan divide over vaccination, experts said, is the president himself. His repeated denigration of scientists and insistence that the pandemic is not a threat, they said, have contributed to a sense among his followers that the vaccine is either not safe or not worth taking.“I just don’t feel there’s been enough research on it. I think it was sped up too fast,” said Mark Davis, 42, a disabled worker in Michigan. “You don’t even really know the side effects, what’s in it.”Mr. Lofgren agreed. “The jury’s out on whether it’s going to work,” he said, despite studies showing that the Pfizer and Moderna vaccines were more than 94 percent effective.Experts say that “herd immunity” — the point at which so many people are immune that the spread of a virus is diminished — can be achieved when roughly 75 percent of the population is vaccinated. While the Trump administration is rolling out a public relations campaign to encourage people to get vaccinated, the reluctance among even a minority of Republicans is deeply troubling to public health experts.Mr. Trump has been quick to claim credit for the manufacturing and distribution of the vaccine. “Distribution to start immediately,” he said Friday on Twitter, a day after an F.D.A. expert advisory panel recommended approval of Moderna’s vaccine.Although the president has recovered from Covid-19, he remains vulnerable to reinfection. Dr. Anthony S. Fauci, the government’s top infectious disease scientist, has recommended that Mr. Trump be vaccinated. But he has given no indication that he will actually do so, and he has said little, if anything, to encourage Americans to get vaccinated.“We need him taking a proactive role,” said Matthew Motta, a political scientist at Oklahoma State University who studies politics and vaccine views, adding, “The single best person to convince you to change your mind about something is somebody who agrees with you, somebody who you trust on other issues.”Mr. Trump’s own flirtations with vaccine skepticism are well known. He repeated the debunked theory that vaccines cause autism as far back as 2007, when he said he had slowed his son Barron’s vaccination schedule, and as recently as 2015 while first running for president.“Trump helped re-energize the anti-vaccine movement,” said Dr. Peter Hotez, an expert on vaccines, “and now he wants to pivot and make this his greatest accomplishment.”Helping speed the development of a coronavirus vaccine may be one of President Trump’s proudest accomplishments, but at least in the early stages of the vaccine rollout, there is evidence that a substantial number of his supporters say they do not want to get it.Credit…Samuel Corum for The New York TimesSome conservative news media outlets are reinforcing the skepticism, tapping into suspicion of government by raising questions about whether officials are leveling with the public about the risks of the vaccines.Tucker Carlson, the Fox News commentator, railed on Thursday against the “corporate image campaign” promoting vaccination, suggesting incorrectly that isolated instances of allergic reactions to the vaccine were being censored.In interviews, Trump supporters said they felt the pandemic had been blown out of proportion. Mr. Lofgren said several of his co-workers had recovered from Covid-19, “with really no more than just cold symptoms.” Mr. Palmer said that if he “had an issue with breathing or a heart issue or a lung issue,” he might consider it, but does not want to take a chance.Conspiracy theories — including the notion that the virus was created by the Chinese and Democrats to hurt Mr. Trump politically, or that the vaccine contains a microchip allowing the government to track people — cropped up in several conversations. Ms. Graves, who has diabetes, a risk factor for Covid-19, and has a master’s degree in library science, said such thoughts were creating doubts in the back of her mind.“There’s no, quote, evidence that there’s a microchip or that here’s something nefarious about the whole thing,” she said. “But I have a gut check about all of it, and the government pushing it, and they’re finding all these popular people to take the vaccine. And it’s weird, like why are we pushing it so hard?”AdvertisementContinue reading the main story More

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    Your Thursday Briefing

    #masthead-section-label, #masthead-bar-one { display: none }The Coronavirus OutbreakliveLatest UpdatesMaps and CasesThe Latest Vaccine InformationU.S. Deaths Surpass 300,000F.A.Q.AdvertisementContinue reading the main storySupported byContinue reading the main storyYour Thursday BriefingCronyism and waste in Britain’s pandemic spending.Dec. 17, 2020Updated 1:08 a.m. ET(Want to get this briefing by email? Here’s the sign-up.)Good morning.We’re covering a new analysis of Britain’s slipshod pandemic spending, a move to the right for Emmanuel Macron and an upside to the climate crisis for Russia.[embedded content]Medical staff wearing personal protective equipment, or P.P.E., at a hospital in Cambridge, England, in May. Officials shelled out billions in contracts for Covid-19 tests, vaccines and P.P.E.Credit…Pool photo by Neil HallCronyism and waste in Britain’s pandemic spendingAs Britain scrambled for protective gear and other equipment, select companies — many of which had close connections to the governing Conservative Party or no previous experience — reaped billions, according to a New York Times analysis of more than 2,500 contracts.In some cases, more qualified companies lost out to those with better political connections, which were granted access to a secretive V.I.P. lane that made them about 10 times more likely to be approved for a contract.Conclusions: While there is no evidence of illegal conduct, there is ample evidence of cronyism, waste and poor due diligence, with officials ignoring or missing red flags, including histories of fraud, human rights abuses, tax evasion and other serious controversies.Christmas restrictions: Prime Minister Boris Johnson has stuck by a pledge to lift limits on gatherings from Dec. 23 to 27 despite growing calls to abandon the plan as coronavirus cases surge.Here are the latest updates and maps of the pandemic.In other developments:The U.S. is negotiating a deal with Pfizer to produce tens of millions of additional doses of its coronavirus vaccine. Vaccinations began in the U.S. on Monday.The number of severe Covid-19 cases in the Gaza Strip sharply increased, raising concerns that hospitals could soon be overwhelmed.In the first week of Britain’s vaccination program, more than 137,000 people have received shots.An international team of 10 scientists working with the World Health Organization will travel next year to China to investigate the origins of the coronavirus.President Emmanuel Macron of France has moved to the right, alienating some former supporters and current members of his own party.Credit…Thomas Coex/Agence France-Presse — Getty ImagesMacron’s pre-election slide to the rightWith an eye on France’s next presidential election in 2022, President Emmanuel Macron has tacked to the right, alienating former liberal supporters and current members of his own party.After recent terrorist attacks, Mr. Macron pushed forward bills on security and Islamist extremism that raised alarms among some French, the United Nations and human rights groups, but won favor among right-leaning voters. Marine Le Pen, the leader of the far-right National Rally, is expected to be his main challenger.Analysis: Despite his center-left origins, Mr. Macron has always been known as a shape-shifter. His slide to the right is regarded by some as a clean break from the first three years of his presidency.Related: A French court found 14 people guilty of aiding the 2015 attack on the magazine Charlie Hebdo, supplying the attackers with cash, weapons and vehicles.Gender equality: The mayor of Paris was fined nearly $110,000 for hiring too many women, under a 2012 law intended to address gender imbalance at senior levels of the country’s Civil Service.A landmark ruling on air pollutionA 9-year-old girl who died of an asthma attack in 2013 became the first person in Britain to officially have air pollution listed as a cause of death, after she was exposed to levels of nitrogen dioxide and particulate matter beyond World Health Organization guidelines.The death of the girl, Ella Adoo-Kissi-Debrah, who was Black, shed a harsh light on how pollution disproportionately affects minorities and deprived families in Britain.Legal experts said it could open a new door to lawsuits by pollution victims or their families. The girl lived near a major road in southeast London. Her mother said that if she had been told air pollution was contributing to her daughter’s ill health, she would have moved.The Coronavirus Outbreak More

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    Your Wednesday Briefing

    #masthead-section-label, #masthead-bar-one { display: none }The Coronavirus OutbreakliveLatest UpdatesMaps and CasesThe Latest Vaccine InformationU.S. Deaths Surpass 300,000F.A.Q.AdvertisementContinue reading the main storySupported byContinue reading the main storyYour Wednesday BriefingPoorer nations struggle to access a coronavirus vaccine.Dec. 15, 2020, 10:06 p.m. ETGood morning.We’re covering the gulf between wealthy and poorer nations for access to a coronavirus vaccine, new laws against civil liberties in Hungary and Brazil’s chaotic vaccine plan.[embedded content] Pillay Jagambrun, a Care home worker, received the Pfizer/BioNTech Covid-19 vaccine at Croydon University Hospital in south London last week.Credit…Pool photo by Dan CharityRich countries are first in line for new virus vaccinesThe world’s wealthiest countries have laid claim to more than half of the doses of coronavirus vaccines coming on the market through 2021, as many poorer nations struggle to secure enough. If all those doses are fulfilled, the E.U. could inoculate its residents twice, Britain and the United States four times over and Canada six times over, according to our data analysis.In the developing world, some countries may be able to vaccinate, at most, 20 percent of their populations in 2021, with some reaching immunity as late as 2024.In many cases, the U.S. made its financial support for the vaccine’s development conditional on getting priority access. The country is heading toward authorizing another vaccine this week, from Moderna.By the numbers: Britain has claimed 357 million doses in total, with options to buy 152 million more, while the European Union has secured 1.3 billion, with as many as 660 million doses more if it chooses.Credit…The New York TimesHere are the latest updates and maps of the pandemic.In other developments:A second wave has brought a new surge in infections to Sweden, leaving Stockholm’s emergency services overrun and forcing the authorities to recalibrate their approach.Russia has released additional results from a clinical trial of its leading coronavirus vaccine, Sputnik V, showing an efficacy rate of 91.4 percent. AstraZeneca opened talks this month about combining efforts.President Cyril Ramaphosa of South Africa announced new restrictions as the country entered a second coronavirus wave, with infections expected to rise over the festive season.The European Medicines Agency said in a statement that it would move forward a meeting to decide whether to approve the Pfizer-BioNTech vaccine to Dec. 21 from Dec. 29.The new amendment would also effectively bar gay couples from adopting children in Hungary by defining a family as including a man as the father and a woman as the mother.Credit…Attila Kisbenedek/Agence France-Presse — Getty ImagesNew laws in Hungary further erode civil libertiesThe Hungarian Parliament on Tuesday passed sweeping measures that curtailed the rights of gay citizens, relaxed oversight of the spending of public funds and made it more difficult for opposition parties to challenge Prime Minister Viktor Orban in future elections.The government justified its actions in a written explanation by saying that the Constitution “is a living framework which expresses the will of the nation, the manner in which we want to live.” Increasingly, “the will of the nation” is becoming indistinguishable from Mr. Orban’s own.Analysis: The new laws are cause for “grave concern,” said Agnes Kovacs, a legal expert. Over more than a decade in power, Mr. Orban has torn at the fabric of democratic institutions in pursuit of what he calls an “illiberal” state.Details: The legislation includes a constitutional amendment that would effectively bar gay couples from adopting children in Hungary by defining a family as including a man as the father and a woman as the mother. The amendment could also make it harder for single parents to adopt.Kenyan soldiers at their base in Tabda, inside Somalia, near the border with Kenya. As part of the African Union peacekeeping forces in Somalia, Kenya has more than 3,600 troops stationed in the country.Credit…Ben Curtis/Associated PressSomalia cuts diplomatic ties with KenyaSomalia severed diplomatic ties with Kenya on Tuesday, accusing the neighboring East African nation of meddling in its internal political affairs. The move came weeks before a crucial general election.“The federal government of Somalia reached this decision as an answer to the political violations and the Kenyan government’s continuous blatant interference recently in our country’s sovereignty,” said Osman Dubbe, the minister of information.Context: The move injects an additional note of instability into an already shaky region, after the U.S. announced plans to withdraw troops from Somalia — which some fear will motivate the Shabab militant group to escalate its offensive across Somalia and the Horn of Africa.If you have 5 minutes, this is worth itBrazil’s chaotic vaccine planCredit…Victor Moriyama for The New York TimesWith its top-notch immunization program and strong pharmaceutical industry, Brazil should be well-placed to curtail infections domestically. But political infighting, haphazard planning and a rising anti-vaccine movement have left the nation without a clear vaccination plan, our reporters found. Above, a vaccine trial in São Paulo this month.Brazilians now have no sense of when a vaccine will come. The coronavirus has brought the public health system to its knees and has crushed the economy. “They’re playing with lives,” one epidemiologist said. “It’s borderline criminal.”Here’s what else is happeningBig Tech: In a bid for tougher oversight of the technology industry, the authorities in the European Union and Britain introduced regulations to pressure the world’s biggest tech companies to take down harmful content and open themselves up to more competition.Uighurs: Prosecutors at the International Criminal Court will not investigate allegations that China committed genocide and crimes against humanity over the mass detention of ethnic Uighurs in the Xinjiang region, saying China is not a party to the court.The Coronavirus Outbreak More