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      Fossils Show Giant Predatory Sea Scorpions Were Distance Swimmers

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      Specimens of what appear to be the largest eurypterid species found in Australia could shed light on the sudden extinction of the massive arthropods.Most modern scorpions would fit in the palm of your hand. But in the oceans of the Paleozoic era more than 400 million years ago, animals known popularly as sea scorpions were apex predators that could grow larger than people in size.“They were effectively functioning as sharks,” said Russell Bicknell, a paleobiologist at the American Museum of Natural History.New research by Dr. Bicknell and colleagues, published Saturday in the journal Gondwana Research and relying on Australian fossils, reveals that the biggest sea scorpions were capable of crossing oceans, a finding that is “absolutely pushing the limits of what we know arthropods could do,” he said.What are commonly known as sea scorpions were a diverse group of arthropods called eurypterids. They came in many shapes and sizes but are perhaps best known for their largest representatives, which could grow to more than nine feet long. With huge claws, a beefy exoskeleton and a strong set of legs for swimming, the larger sea scorpions most likely ruled the seas.However fearsome these arthropods must have been to Paleozoic prey, they went extinct without much of a bang. The fossil record of eurypterids peaked in the Silurian period, which started about 444 million years ago, and they then abruptly died out after the early Devonian period ended about 393 million years ago.That sudden turn of fate has left scientists bewildered.“They appear, they start doing really well, they get very big, and then they go extinct,” said James Lamsdell, a paleobiologist at West Virginia University who was not involved in the study. “For a while they were so dominant, and then they just burned out.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Heat Contributed to 47,000 Deaths in Europe Last Year, but Relief Programs Helped

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      A new study shows that behavioral and social changes can reduce heat mortality. But challenges remain as temperatures continue to rise.More than 47,000 Europeans died from heat-related causes during 2023, the world’s hottest year on record, a new report in Nature Medicine has found.But the number could have been much higher.Without adaptations to rising temperatures over the past two decades — including advances in health care, more widespread air-conditioning and improved public information that kept people indoors and hydrated during extreme temperatures — the death toll for Europeans experiencing the same temperatures at the start of the 21st century could have been 80 percent higher, according to the new study. For people over 80 years old, the death toll could have doubled.“We need to consider climate change as a health issue,” said Elisa Gallo, a postdoctoral researcher at the Barcelona Institute for Global Health, a nonprofit research center, and the lead author of the study. “We still have thousands of deaths caused by heat every year, so we still have to work a lot and we have to work faster.”Counting deaths from extreme heat is difficult, in part because death certificates don’t always reflect the role heat played in a person’s death. The study used publicly available death records in 35 countries, representing about 543 million Europeans and provided by Eurostat, the statistics office of the European Union.The researchers used an epidemiological model to analyze the deaths alongside 2023 weekly temperature records to estimate what fraction of deaths could be attributable to heat.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Piecing Together an Ancient Epic Was Slow Work. Until A.I. Got Involved.

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      Scholars have struggled to identify fragments of the epic of Gilgamesh — one of the world’s oldest literary texts. Now A.I. has brought an “extreme acceleration” to the field.In 1872, in a quiet second-floor room at the British Museum, George Smith, a museum employee, was studying a grime-encrusted clay tablet when he came across words that would change his life. In the ancient cuneiform script, he recognized references to a stranded ship and a bird sent in search of land. After he had the tablet cleaned, Smith was certain he’d found a prototype of the biblical flood story.“I am the first man to read that after more than 2,000 years of oblivion,” Smith reportedly said in a frenzy of excitement.Smith realized that the tablet, which had been excavated in what is modern-day Iraq, was a small part of a much longer work — one that some then thought could help shed light on the Book of Genesis. The discovery made Smith, who came from a working-class family and had largely taught himself cuneiform, famous. He dedicated the rest of his life to searching for missing pieces of the poem, making multiple trips to the Middle East before dying of an illness on his final trip in 1876, at age 36.For 152 years since Smith’s discovery, successive generations of Assyriologists — experts in the study of cuneiform and the cultures that used it — have taken up his quest to piece together a complete version of the poem known now as the Epic of Gilgamesh. Fragments of the epic, which was written more than 3,000 years ago and was based upon still earlier works, have re-emerged as tablets have been unearthed in archaeological digs, found in museum store rooms or surfaced on the black market.The researchers face a daunting task. There are as many as half a million clay tablets housed in the Mesopotamian collections of various world museums and universities, along with many more tablet fragments. But since there are so few experts in cuneiform, many of these writings are unread and many more are unpublished.So despite a generation-spanning effort, about 30 percent of Gilgamesh remains missing and there are gaps in modern understanding both of the poem and Mesopotamian writing in general.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Three MDMA Studies Are Retracted by Scientific Journal

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      The journal Psychopharmacology has retracted three papers about MDMA-assisted therapy based on what the publication said was unethical conduct at one of the study sites where the research took place.Several of the papers’ authors are affiliated with Lykos Therapeutics, the drug company whose application for MDMA-assisted therapy to treat post-traumatic stress disorder was rejected last week by the Food and Drug Administration. The company said the research in the retracted papers was not part of its application to the F.D.A. In declining to approve Lykos’s application, the agency cited concerns about missing data and problems with the way the company’s study was designed, according to a statement released by Lykos on Friday.The F.D.A. has asked Lykos to conduct an additional clinical trial of its MDMA-assisted therapy, which would have been the first psychedelic medicine to win approval by federal regulators. Lykos has said it would appeal the decision.The journal retraction was first reported by Stat, the health and medical news website.On Sunday, Lykos said that it disagreed with Psychopharmacology’s decision and that it would file an official complaint with the Committee on Publication Ethics, a nonprofit that sets guidelines for academic publications.“The articles remain scientifically sound and present important contributions to the study of potential treatments for PTSD,” the company said in the statement.The incident cited by Psychopharmacology has been well documented. In 2015, an unlicensed Canadian therapist who took part in the trial engaged in a sexual relationship with a participant after the conclusion of the trial’s dosing sessionsIn civil court documents, the patient, Meaghan Buisson, said she was sexually assaulted by the therapist, Richard Yensen, who at the time was working alongside his wife, a licensed therapist. Mr. Yensen has said the relationship was consensual and initiated by Ms. Buisson. Six months after the final session, she moved from Vancouver to Cortes Island, in British Columbia, where the couple lived, according to court documents. The relationship between patient and practitioner continued for more than a year, the documents said. Professional associations in both Canada and the United States prohibit sexual relationships between psychologists and patients for at least two years after their final session. The incident helped highlight some of the challenges associated with psychedelic medicine, which can render patients especially vulnerable during dosing sessions. For that reason, most clinical trials involving psychedelic compounds require the presence of two mental health professionals. (Lykos’s trials with MDMA require only one of the practitioners to be licensed.)The Multidisciplinary Association for Psychedelic Studies, or MAPS, is the nonprofit that carried out the research and later created Lykos to market its proprietary MDMA-assisted therapy. The association publicly acknowledged the incident in 2019, adding that it had been reported to the F.D.A. and to Canadian health authorities.The company acknowledged on Sunday that it had failed to notify Psychopharmacology about the violations, but it said that the oversight should have been addressed through a correction, not a retraction. More

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      Ancient Calendar, Recently Discovered, May Document a Long-Ago Disaster

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      The markings on a pillar in southern Turkey are more than decorations on the stone, a researcher at the University of Edinburgh says. They may memorialize a time when comet fragments struck Earth.A researcher at the University of Edinburgh has discovered what he believes is the earliest calendar of its kind at Gobekli Tepe, an archaeological excavation site in what is now southern Turkey that used to be an ancient complex of temple-like enclosures.The researcher, Martin Sweatman, a scientist at the University of Edinburgh, said in research published last month that V-shaped markings on the lunisolar calendar, which combines the movements of the moon and sun, recorded a major astronomical event that had a huge impact on Earth — making the ancient pillar part of an ancient version of a memorial.Dr. Sweatman said that the intricate carvings at Gobekli Tepe tell the story and document the date when fragments of a comet — which came from a meteor stream — hit Earth roughly 13,000 years ago. The comet strike, which the latest research has placed in the year 10,850 B.C., has long been a source of disagreement among academics and researchers.This is not the first time that Dr. Sweatman has been able to connect the impact of the comet to the site in Turkey, he said. In 2017, he linked the two in an academic paper in which he contended that the carvings at Gobekli Tepe were memorialized in the pillars, and that the site was used as a place to observe space.At the time, a group of excavators at Gobekli Tepe challenged those findings. Jens Notroff, an archaeologist who wrote the post on the excavators’ website, was not immediately convinced about the new findings and questioned whether the markings had a deeper meaning. He said on the social media platform X that there was an “an obsession with the idea that there *must* be a secret, a hidden code which needs to and can be decoded — while it’s really just about past humans living their lives.”Dr. Sweatman said the recent discovery that one of the pillars also depicts a lunisolar calendar — and thus marks the day of the impact — lined up with his prior research. “We can be very confident indeed that it’s a date,” he said.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      FDA Declines to Approve MDMA Therapy, and Seeks Further Study

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      The agency said there was insufficient data to allow the use of a treatment for PTSD that involves the drug known as Ecstasy.The Food and Drug Administration on Friday declined to approve MDMA-assisted therapy for the treatment of post-traumatic stress disorder, dealing a serious blow to the nascent field of psychedelic medicine and dashing the hopes of many Americans who are desperate for new treatments.The F.D.A. said there was insufficient data to allow its use, and it asked the company seeking approval for the treatment, Lykos Therapeutics, to conduct an additional clinical trial to assess whether the drug, commonly known as Ecstasy or molly, would be safe and effective.An additional clinical trial could add years, and millions of dollars, to the approval process.If approved, MDMA would have become the first psychedelic compound to be regulated by federal health authorities. Supporters of psychedelic medicine were deeply disappointed, and some said they were stunned, having assumed the therapy’s promising data would overcome flaws in the company’s clinical trials, which had been designed in consultation with F.D.A. scientists.“This is an earthquake for those in the field who thought F.D.A. approval would be a cinch,” said Michael Pollan, the best-selling author and co-founder of the UC Berkeley Center for the Science of Psychedelics. His book, “How to Change Your Mind,” helped catalyze public interest in the therapeutic potential of psychoactive compounds, demonized during the nation’s long war on drugs.But the agency’s decision had not been entirely unexpected, after a group of independent experts convened by the F.D.A. to evaluate Lykos’s data met in June and did not recommend the treatment. On two central questions, the experts voted overwhelmingly that the company had not proven the treatment was effective, and that the drug therapy’s benefits did not outweigh the risks.The agency generally follows the recommendations of its outside panels. Critics, however, have questioned the panel’s expertise, noting that only one of its 11 members had experience in psychedelic medicine.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Heat Raises Fears of ‘Demise’ for Great Barrier Reef Within a Generation

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      A new study found that temperatures in the Coral Sea have reached their highest levels in at least four centuries.This generation will probably see the demise of the Great Barrier Reef unless humanity acts with far more urgency to rein in climate change, according to scientists in Australia who released new research on heat in the surrounding ocean.The Great Barrier Reef is the largest coral reef system in the world and is often called the largest living structure on Earth. The study, published on Wednesday in the journal Nature, found that recent extreme temperatures in the Coral Sea are at their highest in at least 400 years, as far back as their analysis could reach.It included modeling that showed what has been driving those extremes: Greenhouse gas emissions caused by humans burning fossil fuels and destroying natural places that store carbon, like forests.“The heat extremes are occurring too often for those corals to effectively adapt and evolve,” said Ben Henley, a paleoclimatologist at the University of Melbourne and an author of the new study. “If we don’t divert from our current course, our generation will likely witness the demise of one of Earth’s great natural wonders, the Great Barrier Reef.”The study’s scientific prose put it this way: “The existential threat to the Great Barrier Reef ecosystem from anthropogenic climate change is now realized.”Tanya Plibersek, Australia’s environment minister, said in a statement that the government understood its responsibility to act on climate change and safeguard the reef. She pointed to a recent law that calls for a 43 percent reduction of emissions by 2030 and to $1.2 billion in measures to protect the reef.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More