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    Novo Nordisk to Replace C.E.O. After Losing Edge in Weight-Loss Drugs

    The Danish drugmaker, which makes Ozempic and Wegovy, has seen its stock tumble as competition in the weight-loss drug market has grown fiercer.Novo Nordisk will replace its chief executive, Lars Fruergaard Jorgensen, the company announced Friday, citing a sharp decline in its stock price that stemmed from increased competition for its popular weight-loss drug.The Danish drugmaker said it was searching for a new chief executive to soon replace Mr. Jorgensen, who has led Novo Nordisk for eight years.The move reflects a remarkable fall in fortune for the maker of one of the most well-known drugs in the world, which is sold as Ozempic for diabetes and Wegovy for obesity. The company’s stock has fallen by 50 percent in the past year.

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    Novo Nordisk’s share price
    Source: FactSetBy The New York TimesSales of that drug created boom times for Novo Nordisk. In 2023, the company’s extraordinary success prompted the Danish central bank to keep interest rates lower than it otherwise would. For more than a year, Novo Nordisk’s market value surpassed Denmark’s entire gross domestic product.But investors have soured on the company as it has faced increasingly fierce competition. Lower-cost copycat versions of the weight-loss drugs made through a process known as compounding have cut into Novo Nordisk’s sales. Even more damaging has been competition from Eli Lilly, the maker of the drug sold as Mounjaro and Zepbound.Novo Nordisk had a head start, winning approval to market its drug for obesity more than two years before Eli Lilly. But Novo Nordisk has been rapidly losing market share to its competitor: American patients have filled more prescriptions this year for Zepbound than for Wegovy, and the gap has been widening, according to the industry data provider IQVIA.Eli Lilly is also developing new weight-loss drugs, including a daily pill, that are expected to set up years of blockbuster sales for the company. Novo Nordisk has a hazier path forward. More

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    Asia Stocks Rise on Hope for Lower Tariffs After U.S.-China Talks

    Investors were optimistic after American officials touted progress in trade negotiations over the weekend, though details had yet to be released.Stocks in Asia gained on Monday after weekend talks signaled that progress had been made in easing trade tensions between the United States and China.Benchmark indexes in Japan and South Korea edged higher in early trading on Monday morning. Stocks in Hong Kong and Shenzhen in China climbed about 1 percent, while futures pointed to similar gains for the S&P 500 when trading begins in New York.Meetings in Geneva between U.S. and Chinese officials concluded on Sunday with Scott Bessent, the U.S. Treasury secretary, saying that “substantial progress” had been made. China’s vice premier, He Lifeng, called the talks “candid, in-depth and constructive.” Details are expected to be released on Monday, both sides said.The meetings were the first between Washington and Beijing since President Trump ratcheted up tariffs on Chinese imports to 145 percent and China retaliated with its own taxes of 125 percent on U.S. goods. The tariffs are so high as to effectively block much of the trade between the two countries.The escalating trade war has left financial markets uneasy, and the meeting raised investors’ hopes that tariffs could eventually be lowered.Analysts at the financial services firm Wedbush Securities said the talks were a “positive step in the right direction.” They anticipated that an initial agreement, once unveiled during the U.S. day on Monday, would “at a minimum” involve a “much lower level” for tariffs.Economists have warned that the tit-for-tat trade barriers have significantly increased the possibility of an economic downturn. That includes in Asia, where some of the biggest economies, including Japan and South Korea, are heavily reliant on both China and the United States as trade partners.The World Trade Organization has forecast that the continuing division of the global economy into “rival blocs” could cut global gross domestic product by nearly 7 percent over the long run. Earlier this month, Japanese officials slashed their growth forecast for this year by more than half.Last week, China reported that its exports to the United States in April dropped 21 percent from a year earlier. Recession warnings are beginning to emerge in the United States.Heading into the weekend, investors had relatively low expectations for a breakthrough at the talks that would result in a meaningful reduction in tariffs. Many analysts expected the discussions to revolve around determining what each side wanted and how negotiations could move forward.Recently, Mr. Trump has opened the door to lower tariffs. Last week, he suggested that tariffs could come down to 80 percent. Commerce Secretary Howard Lutnick told Fox News that so-called reciprocal tariffs on trade with China may settle near 34 percent. More

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    Bessent Pitches Skittish Investors to Bet on Trump’s Economic Plan

    The Treasury secretary urged executives and entrepreneurs to look beyond the Trump administration’s trade agenda.Treasury Secretary Scott Bessent urged skittish global business leaders on Monday to ignore President Trump’s economic naysayers and ramp up investment in the United States, defending an economic agenda that economists warn will slow economic growth and exacerbate inflation.Speaking to executives, entrepreneurs and policymakers, Mr. Bessent argued that the Trump administration’s economic plans go beyond trade policy and will pay off in the long run. He urged them to also focus on Mr. Trump’s plans to cut taxes and regulation, which he said would spur job creation and output.“Tariffs are engineered to encourage companies like yours to invest directly in the United States,” Mr. Bessent said in remarks at the Milken Institute Global Conference in Los Angeles. “You’ll be glad you did — not only because we have the most productive work force in the world. But because we will soon have the most favorable tax and regulatory environment as well.”His comments came just hours after Mr. Trump ordered up new tariffs on foreign film producers, a decision that left many in Hollywood puzzled about how such a tax would work.The Treasury Secretary has been working to ease concerns among investors that Mr. Trump’s trade plans will destabilize the global economy. Mr. Trump last month levied tariffs on countries around the world and escalated a trade fight with China, which sent financial markets plunging.Since then, Mr. Bessent has been racing to negotiate trade deals with dozens of countries. He has also signaled that the China tariffs are not sustainable, offering hope that Mr. Trump would soon begin negotiations to lower them.”Our goal with trade policy is to level the playing field for our great American workers and companies,” Mr. Bessent said.The Trump administration is working closely with congressional Republicans ]on tax legislation that would extend the 2017 tax cuts and offer new tax breaks for overtime pay, tips and Social Security benefits. Mr. Bessent made the case on Monday that investors need to consider the broader agenda when thinking about where to park their money.Describing Mr. Trump’s policies as “mutually reinforcing,” Mr. Bessent said, “acting in concert, they push toward the same goal — to solidify our position as the home of global capital.”Investors have grown increasingly wary of Mr. Trump’s policies in recent months, with stocks, bonds and the dollar all showing signs of weakness as fund managers fret over the uncertainty surrounding Mr. Trump’s policymaking approach.The International Monetary Fund projected last month that global output will slow to 2.8 percent this year from 3.3 percent in 2024 and sharply downgraded its outlook for the U.S. economy.On Monday, Mr. Bessent said that Mr. Trump would prove “critics in establishment circles” wrong.“We have the world’s reserve currency, the deepest and most liquid markets, and the strongest property rights,” Mr. Bessent said. “For these reasons, the United States is the premier destination for international capital.” More

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    Under Trump, Stocks Have the Worst Start to a Presidential Term Since 1974

    During the first 100 days of the Trump administration, shock waves from the chaotic tariff rollout continue to send tremors through the global financial system.One hundred days of President Trump. Seventy days of whipsaw trading in financial markets. Thirty three days of losses. More than $6.5 trillion wiped from the value of public companies.For financial markets, the 9 percent drop in the S&P 500 is on track for the worst start to a presidential term since Gerald R. Ford took over from Richard M. Nixon in August 1974 after the Watergate scandal. The slump is worse even than when the tech bubble burst at the turn of the century, and George W. Bush inherited a market already in free fall.In contrast, Mr. Trump inherited an economy on solid footing and a stock market rising from one record high to another.That swiftly changed when Mr. Trump unveiled his marquee suite of tariffs on April 2 — not the first new import taxes announced by his administration, but by far the most sweeping. Volatility erupted. Wall Street frantically began to grapple with the economic consequences of the new government’s policies.The S&P 500 tumbled more than 10 percent in two days, a drop comparable to some of the worst days of the pandemic-induced sell-off in March 2020 and, before that, the financial crisis in 2008.Stocks have since stabilized, but the shock waves from the chaotic tariff rollout continue to send tremors through the global financial system.Trump’s Astonishing 100 Days, in 8 ChartsBy many measures, the opening months of President Trump’s second term stand apart from those of essentially any modern president.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Stocks Edge Higher Amid Trump Tariff Uncertainty

    The Trump administration’s chaotic tariff rollout continues to spur volatility in the markets.Stocks inched higher in early trading on Tuesday, as the Trump administration’s chaotic tariff rollout continues to spur volatility in the markets.The S&P 500 opened up 0.5 percent, and the technology-heavy Nasdaq also gained slightly. President Trump’s whipsawing tariff policies are still driving sentiment on Wall Street, especially in sectors facing the threat of more levies or potential reprieves.Here’s what else to know:Bank stocks rose on Tuesday, as major U.S. lenders reported their latest earnings. Bank of America surpassed Wall Street’s profit and revenue expectations, and its shares rose about 5 percent Tuesday morning. Citigroup’s profits also beat estimates, sending its stock more than 2 percent higher.Tariff threats are taking center stage in the pharmaceutical and technology sectors, after the Trump administration on Monday took steps that appeared likely to result in new tariffs on pharma products and semiconductors. Shares in drugmaker Eli Lilly were up slightly on Tuesday morning, while Novartis stock was trading roughly flat. Shares in chip giant Nvidia were nearly 2 percent higher, after the company on Monday said it would invest in artificial intelligence infrastructure in the United States.Shares in Boeing, the aviation giant, fell about 1.5 percent on Tuesday following a report from Bloomberg News that China had instructed its airlines to halt deliveries of Boeing planes after the Trump administration imposed steep tariffs on Chinese goods.In the auto industry, shares in General Motors, Ford Motor and Stellantis — which jumped on Monday after Mr. Trump signaled that he might offer car companies some relief from tariffs — were mixed on Tuesday morning. Shares in General Motors and Ford both fell more than 1 percent, while Stellantis rose about a half percent. The sector, which is grappling with a 25 percent tariff on imported vehicles, is bracing for new levies on imported car parts.The U.S. dollar, long a haven in global financial markets, has been falling against other major currencies. But an index that tracks the currency against a basket of major trading partners stabilized early Tuesday, ending a five-day slide. More

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    Stocks Notch Gains After More Tariff Whiplash

    After exempting Chinese imports of smartphones, chips and other electronics, President Trump said on Sunday the carve outs were only temporary.Markets in Asia moved higher on Monday after a weekend that brought more shifts in strategy from President Trump about tariffs.Stocks in Japan rose a little over 1 percent while benchmarks went up 2 percent in Hong Kong and less than 1 percent in mainland China. S&P 500 stock futures, which let investors bet on how the index might perform when it opens in New York, were about 0.50 percent higher.The modest rally followed another chaotic week on Wall Street, with the S&P 500 starting with losses but ending with its best weekly performance since November 2022. The gains were driven by Mr. Trump’s announcement on Wednesday that he would pause for 90 days the “reciprocal” tariffs he had imposed on dozens of countries just a week earlier.On Friday night, after Mr. Trump had repeatedly said he would spare no industry, U.S. customs officials exempted a host of technology products imported from China. That means smartphones, semiconductors, computers and other equipment would not face most of the 145 percent tariffs Mr. Trump has imposed on China.The carve outs were viewed as a win for Apple and other American tech giants because tech products and components are a key part of American imports from China. A spokesperson for China’s Ministry of Commerce on Sunday called it a “small step” in “correcting” the tariffs Mr. Trump has put on China.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Stock Ownership Is What Really Divides Americans

    In a pamphlet published in 1711, Jonathan Swift lamented the “folly” of those who “mistake the echo of a London coffeehouse for the voice of the kingdom.” Those informal salons were, he wrote, frequented by people whose wealth depended on their shares in the Bank of England or the East India Company or “some other stock.” If the responses to the Trump administration’s tariff policies have shown us anything, it is that, like most of the ills against which Swift railed, this unfortunate tendency to conflate stockholders with the nation remains very much with us.The greatest division in American life is not between so-called red and blue states, or between urban and rural citizens, but instead between those who own stock and those who do not. For those who do, economic security can be measured in portfolio statements; the rest — roughly 40 percent of Americans — must make do with such antiquated metrics as the cost of housing or even the price of eggs.This division is not merely economic; it is also ideological. Though many Americans own at least some stock, 10 percent of Americans own 93 percent of it. Yet the elite stock-owning class has convinced itself that what is good for the S&P 500 is good for America. Worse, many Americans who own stock through retirement plans or pension plans have been convinced to believe this, too, even though their interests tend not to align neatly with those of multimillionaires.The result is a kind of ideological capture in which any policy that does not serve the immediate interests of shareholders is dismissed as reckless, radical or economically illiterate. The common good, insofar as it is considered at all, must first be translated into the language of market returns. Can anything be good if it does not make the line go up? The question (we are told) answers itself.Like awed visitors to the oracle at Delphi, we consult the Dow Jones and the S&P 500 with solemn credulity, and their half-random fluctuations are taken as portents of divine favor, or else as intimations of the coming wrath of heaven’s gracious ones. All presidents — including Donald Trump — genuflect before this altar, and most of us implicitly regard any policy that displeases the great god Wall Street as a kind of sacrilege. We treat the stock market as the final arbiter of our collective well-being.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Trump’s Encouragement of Stock Investors Draws Scrutiny

    Was the president manipulating the market with his comments, as his critics say, or reassuring Americans, as the White House maintains?President Trump began his Wednesday with some advice for those rattled by his steep tariffs.“BE COOL,” Mr. Trump told his followers on social media after the markets opened. Just a couple of minutes later he wrote, “THIS IS A GREAT TIME TO BUY!!!”Hours after that, Mr. Trump sent the markets soaring when he paused the levies for 90 days. The S&P 500 climbed several percentage points in a matter of minutes and was on its way to its best day since the recovery of the 2008 financial crisis.Soon after Mr. Trump’s pause, Democrats and government ethics experts asked the perhaps obvious question: Did Mr. Trump give the green light to his followers to cash in on a forthcoming rise in stock prices?“How is this not market manipulation?” Representative Mike Levin, Democrat of California, said on social media, referring to action that is potentially illegal. “If you’re a Trump supporter and you did what he said and you bought, then you did great. On the other hand, if you’re a retiree or a senior or somebody in the middle class over the last few days that didn’t have the tolerance for risk and you decided to sell, you got screwed.”The news of Mr. Trump’s pause came as Jamieson Greer, the U.S. trade representative, was testifying on Capitol Hill. Representative Steven Horsford, Democrat of Nevada, pressed him on Mr. Trump’s aim.“It’s not market manipulation,” Mr. Greer said. “We’re trying to reset the global trading system.”“How have you achieved any of that?” Mr. Horsford asked. “So if it’s not market manipulation, what is it? Who’s benefiting? What billionaire just got richer?”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More