Vaccination and Immunization

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      Trump Administration Demands Additional Cuts at C.D.C.

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      In addition to reductions at agency personnel, federal regulators are demanding $2.9 billion in contract cancellations, The Times has learned.Alongside extensive reductions to the staff of the Centers for Disease Control and Prevention, the Trump administration has asked the agency to cut $2.9 billion of its spending on contracts, according to three federal officials with knowledge of the matter.The administration’s cost-cutting program, called the Department of Government Efficiency, asked the public health agency to sever roughly 35 percent of its spending on contracts about two weeks ago. The C.D.C. was told to comply by April 18, according to the officials.The cuts promise to further hamstring an agency already reeling from the loss of 2,400 employees, nearly one-fifth of its work force. On Tuesday, the administration fired C.D.C. scientists focused on environmental health and asthma, injuries, violence prevention, lead poisoning, smoking and climate change.Officials at the White House and the Department of Health and Human Services did not immediately respond to requests for comment.Abruptly cutting 35 percent of contracts would be tough for any organization or business, said Tom Inglesby, director of the Johns Hopkins Center for Health Security at the Bloomberg School of Public Health, who advised the Biden administration during Covid.“Sure, any manager can find small savings and improvements, but these kinds of demands are of the size and speed that break down organizations,” he said. “This is not the way to do good for the public or for the public’s health.”The C.D.C.’s largest contract, about $7 billion per year, goes to the Vaccines for Children Program, which purchases vaccines for parents who may not be able to afford them. That program is mandated by law and will not be affected by the cuts, according to one senior official who spoke on condition of anonymity.But other C.D.C. contracts include spending on computers and other technology, security guards, cleaning services and facilities management. The agency also hires people to build and maintain data systems and for specific research projects. Over the past several years, contracts have also supported activities related to Covid-19, one official said.Separately, H.H.S. last week abruptly discontinued C.D.C. grants of about $11.4 billion to states that were using the funds to track infectious diseases and to support mental health services, addiction treatment and other urgent health issues.At least some of the contracts D.O.G.E. is now asking the agency to discontinue may no longer be implemented because the people overseeing them have been fired. This is not the first time D.O.G.E. asked the agency to cut funding. It previously asked the C.D.C. to cut grants to Columbia University and University of Pennsylvania, saying those institutions had failed to take action against antisemitism on campus. “Funding grants and contracts are the mechanism by which we get things done,” said one C.D.C. scientist who asked to remain anonymous because of a fear of retaliation. “They are cutting off our arms and legs.” More

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      Shingles Vaccine Can Decrease Risk of Dementia, Study Finds

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      A growing body of research suggests that preventing the viral infection can help stave off cognitive decline.Getting vaccinated against shingles can reduce the risk of developing dementia, a large new study finds.The results provide some of the strongest evidence yet that some viral infections can have effects on brain function years later and that preventing them can help stave off cognitive decline.The study, published on Wednesday in the journal Nature, found that people who received the shingles vaccine were 20 percent less likely to develop dementia in the seven years afterward than those who were not vaccinated.“If you’re reducing the risk of dementia by 20 percent, that’s quite important in a public health context, given that we don’t really have much else at the moment that slows down the onset of dementia,” said Dr. Paul Harrison, a professor of psychiatry at Oxford. Dr. Harrison was not involved in the new study, but has done other research indicating that shingles vaccines lower dementia risk.Whether the protection can last beyond seven years can only be determined with further research. But with few currently effective treatments or preventions, Dr. Harrison said, shingles vaccines appear to have “some of the strongest potential protective effects against dementia that we know of that are potentially usable in practice.”Shingles cases stem from the virus that causes childhood chickenpox, varicella-zoster, which typically remains dormant in nerve cells for decades. As people age and their immune systems weaken, the virus can reactivate and cause shingles, with symptoms like burning, tingling, painful blisters and numbness. The nerve pain can become chronic and disabling.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Trump Administration Has Begun a War on Science, Researchers Say

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      Nearly 2,000 scientists urged that Congress restore funding to federal agencies decimated by recent cuts.Some 1,900 leading researchers accused the Trump administration in an open letter on Monday of conducting a “wholesale assault on U.S. science” that could set back research by decades and that threatens the health and safety of Americans.The letter’s signatories, all of them elected members of the National Academies of Sciences, Engineering and Medicine, warned of the damage being done by layoffs at health and science agencies and cuts and delays to funding that has historically supported research inside the government and across American universities.“For over 80 years, wise investments by the U.S. government have built up the nation’s research enterprise, making it the envy of the world,” the letter said. “Astoundingly, the Trump administration is destabilizing this enterprise by gutting funding for research, firing thousands of scientists, removing public access to scientific data and pressuring researchers to alter or abandon their work on ideological grounds.”Read the LetterResearchers at academic institutions nationwide say that U.S. science is being dismantled.Read Document 75 pagesThe letter said that many universities and research institutions had so far “kept silent to avoid antagonizing the administration and jeopardizing their funding.” But, it said, “the nation’s scientific enterprise is being decimated.”The signatories called on Americans to appeal to Congress to protect scientific funding.With Elon Musk’s efforts to cut spending and President Trump’s crackdown on institutions he sees as ideological enemies, the administration has sought to dismantle parts of the federal government’s scientific funding apparatus.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Top FDA Vaccine Official Resigns, Citing Kennedy’s ‘Misinformation and Lies’

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      The Food and Drug Administration’s top vaccine official, Dr. Peter Marks, resigned under pressure Friday and said that Health Secretary Robert F. Kennedy Jr.’s aggressive stance on vaccines was irresponsible and posed a danger to the public.“It has become clear that truth and transparency are not desired by the secretary, but rather he wishes subservient confirmation of his misinformation and lies,” Dr. Marks wrote to Sara Brenner, the agency’s acting commissioner. He reiterated the sentiments in an interview, saying: “This man doesn’t care about the truth. He cares about what is making him followers.”Dr. Marks resigned after he was summoned to the Department of Health and Human Services Friday afternoon and told that he could either quit or be fired, according to a person familiar with the matter.Dr. Marks led the agency’s Center for Biologics Evaluation and Research, which authorized and monitored the safety of vaccines and a wide array of other treatments, including cell and gene therapies. He was viewed as a steady hand by many during the Covid pandemic but had come under criticism for being overly generous to companies that sought approvals for therapies with mixed evidence of a benefit.His continued oversight of the F.D.A.’s vaccine program clearly put him at odds with the new health secretary. Since Mr. Kennedy was sworn in on Feb. 13, he has issued a series of directives on vaccine policy that have signaled his willingness to unravel decades of vaccine safety policies. He has rattled people who fear he will use his powerful government authority to further his decades-long campaign of claiming that vaccines are singularly harmful, despite vast evidence of their role in saving millions of lives worldwide.“Undermining confidence in well-established vaccines that have met the high standards for quality, safety and effectiveness that have been in place for decades at F.D.A. is irresponsible, detrimental to public health, and a clear danger to our nation’s health, safety and security,” Dr. Marks wrote.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      U.S. to End Vaccine Funds for Poor Countries

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      A 281-page spreadsheet obtained by The Times lists the Trump administration’s plans for thousands of foreign aid programs.The Trump administration intends to terminate the United States’ financial support for Gavi, the organization that has helped purchase critical vaccines for children in developing countries, saving millions of lives over the past quarter century, and to significantly scale back support for efforts to combat malaria, one of the biggest killers globally.The administration has decided to continue some key grants for medications to treat H.I.V. and tuberculosis, and food aid to countries facing civil wars and natural disasters.Those decisions are included in a 281-page spreadsheet that the United States Agency for International Development sent to Congress Monday night, listing the foreign aid projects it plans to continue and to terminate. The New York Times obtained a copy of the spreadsheet and other documents describing the plans.The documents provide a sweeping overview of the extraordinary scale of the administration’s retreat from a half-century-long effort to present the United States to the developing world as a compassionate ally and to lead the fight against infectious diseases that kill millions of people annually.The cover letter details the skeletal remains of U.S.A.I.D. after the cuts, with most of its funding eliminated, and only 869 of more than 6,000 employees still on active duty.In all, the administration has decided to continue 898 U.S.A.I.D. awards and to end 5,341, the letter says. It says the remaining programs are worth up to $78 billion. But only $8.3 billion of that is unobligated funds — money still available to disburse. Because that amount covers awards that run several years into the future, the figure suggests a massive reduction in the $40 billion that U.S.A.I.D. used to spend annually.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      How Covid Changed the Lives of These 29 Americans

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      Five years ago, Covid took hold and the world transformed almost overnight. As routines and rituals evaporated, often replaced by grief, fear and isolation, many of us wondered: When will things go back to normal? Could they ever? Today, for many, the coronavirus pandemic seems far away and foggy, while for others it’s as visceral […] More

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      30 Charts That Show How Everything Changed in March 2020

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      We left a world we might not get back to. Many things that we took for granted never returned to their former levels, with no guarantee they ever will. The pandemic took a hammer to society and left us struggling to climb back from shutdowns, from fear and from illness. It can be easy, in […] More

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      C.D.C. Will Investigate Debunked Link Between Vaccines and Autism

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      The Centers for Disease Control and Prevention is planning to conduct a large-scale study to re-examine whether there is a connection between vaccines and autism, federal officials said Friday.Dozens of scientific studies have failed to find evidence of a link. But the C.D.C. now falls under the purview of Health and Human Services Secretary Robert F. Kennedy Jr., who has long expressed skepticism about the safety of vaccines and has vowed to revisit the data.“As President Trump said in his Joint Address to Congress, the rate of autism in American children has skyrocketed. C.D.C. will leave no stone unturned in its mission to figure out what exactly is happening,” Andrew Nixon, a spokesman for the Department of Health and Human Services, said in a statement Friday. Mr. Nixon did not offer details about the scope or methods of the project. News of the study was first reported Friday morning by Reuters.In pursuing the study, the C.D.C. is defying the wishes of the chairman of the Senate Health Committee, Senator Bill Cassidy, who said this week that further research into any supposed link between vaccines and autism would be a waste of money and a distraction from research that might shed light on the “true reason” for a rise in autism rates.“It’s been exhaustively studied,” Mr. Cassidy, a doctor, said during the confirmation hearing for Dr. Jay Bhattacharya, President Trump’s nominee to lead the National Institutes of Health. “The more we pretend like this is an issue, the more we will have children dying from vaccine-preventable diseases.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More