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    Shingles Vaccine Can Decrease Risk of Dementia, Study Finds

    A growing body of research suggests that preventing the viral infection can help stave off cognitive decline.Getting vaccinated against shingles can reduce the risk of developing dementia, a large new study finds.The results provide some of the strongest evidence yet that some viral infections can have effects on brain function years later and that preventing them can help stave off cognitive decline.The study, published on Wednesday in the journal Nature, found that people who received the shingles vaccine were 20 percent less likely to develop dementia in the seven years afterward than those who were not vaccinated.“If you’re reducing the risk of dementia by 20 percent, that’s quite important in a public health context, given that we don’t really have much else at the moment that slows down the onset of dementia,” said Dr. Paul Harrison, a professor of psychiatry at Oxford. Dr. Harrison was not involved in the new study, but has done other research indicating that shingles vaccines lower dementia risk.Whether the protection can last beyond seven years can only be determined with further research. But with few currently effective treatments or preventions, Dr. Harrison said, shingles vaccines appear to have “some of the strongest potential protective effects against dementia that we know of that are potentially usable in practice.”Shingles cases stem from the virus that causes childhood chickenpox, varicella-zoster, which typically remains dormant in nerve cells for decades. As people age and their immune systems weaken, the virus can reactivate and cause shingles, with symptoms like burning, tingling, painful blisters and numbness. The nerve pain can become chronic and disabling.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    New York Court Blocks Texas From Filing Summons Against Doctor Over Abortion Pills

    The showdown catapults the interstate abortion wars to a new level.A New York state court on Thursday blocked Texas from filing a legal action against a New York doctor for prescribing and sending abortion pills to a Texas woman.The unprecedented move catapults the interstate abortion wars to a new level, setting the stage for a high-stakes legal battle between states that ban abortion and states that support abortion rights.The dispute is widely expected to reach the Supreme Court, pitting Texas, which has a near-total abortion ban, against New York, which has a shield law that is intended to protect abortion providers who send medications to patients in other states.New York is one of eight states that have enacted “telemedicine abortion shield laws” after the Supreme Court overturned the national right to an abortion in 2022. The laws prevent officials from extraditing abortion providers to other states or from responding to subpoenas and other legal actions — a stark departure from typical interstate practices of cooperating in such cases.The action by the New York court is the first time that an abortion shield law has been used.This case involves Dr. Margaret Daley Carpenter of New Paltz, N.Y., who works with telemedicine abortion organizations to provide abortion pills to patients across the country. In December, the Texas attorney general, Ken Paxton, sued Dr. Carpenter, who is not licensed in Texas, accusing her of sending abortion pills to a Texas woman, in violation of the state’s ban.Dr. Carpenter and her lawyers did not respond to the lawsuit and did not show up for a court hearing last month in Texas. Judge Bryan Gantt of Collin County District Court issued a default judgment, ordering Dr. Carpenter to pay a penalty of $113,000 and to stop sending abortion medication to Texas.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    F.D.A. Expands Access to Clozapine, a Key Treatment for Schizophrenia

    Federal regulators will no longer require patients to provide blood tests before receiving the drug from pharmacies.The Food and Drug Administration has taken a crucial step toward expanding access to the antipsychotic medication clozapine, the only drug approved for treatment-resistant schizophrenia, among the most devastating of mental illnesses.The agency announced on Monday that it was eliminating a requirement that patients submit blood tests before their prescriptions can be filled.Clozapine, which was approved in 1989, is regarded by many physicians as the most effective available treatment for schizophrenia, and research shows that the drug significantly reduces suicidal behavior. Clozapine is also associated with a rare side effect called neutropenia, a drop in white blood cell counts that, in its most severe form, can be life-threatening.In 2015, federal regulators imposed a regimen known as risk evaluation and mitigation strategies, or REMS, that required patients to submit to weekly, biweekly and monthly blood tests that had to be uploaded onto a database and verified by pharmacists.Physicians have long complained that, as a result, clozapine is grossly underutilized.Dr. Frederick C. Nucifora, director of the Adult Schizophrenia Clinic at the Johns Hopkins School of Medicine, said he believed that around 30 percent of patients with schizophrenia would benefit from clozapine — far more than the 4 percent who currently take it.“I have had many patients who were doing terribly, who struggled to function outside the hospital, and cycled through many medications,” he said. “If they go on clozapine, they really tend to not be hospitalized again. I’ve had people go on to finish college and work. It’s quite remarkable.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Trump’s Choices for Health Agencies Suggest a Shake-Up Is Coming

    The picks to oversee public health have all pushed back against Covid policies or supported ideas that are outside the medical mainstream.A longtime leader of the anti-vaccine movement. A highly credentialed surgeon. A seven-term Florida congressman. A Fox News contributor with her own line of vitamins.President-elect Donald J. Trump’s eclectic roster of figures to lead federal health agencies is almost complete — and with it, his vision for a sweeping overhaul is coming into focus.Mr. Trump’s choices have varying backgrounds and public health views. But they have all pushed back against Covid policies or supported ideas that are outside the medical mainstream, including an opposition to vaccines. Together, they are a clear repudiation of business as usual.“What they’re saying when they make these appointments is that we don’t trust the people who are there,” said Dr. Paul Offit, director of the Vaccine Education Center at Children’s Hospital of Philadelphia and an adviser to the Food and Drug Administration.Some doctors and scientists are bracing themselves for the gutting of public health agencies, a loss of scientific expertise and the injection of politics into realms once reserved for academics. The result, they fear, could be worse health outcomes, more preventable deaths and a reduced ability to respond to looming health threats, like the next pandemic. “I’m very, very worried about the way that this all plays out,” Dr. Offit said.But other experts who expressed concerns about anti-vaccine views at the helms of the nation’s health agencies said that some elements of the picks’ unorthodox approaches were welcomed. After a pandemic that closed schools across the country and killed more than one million Americans, many people have lost faith in science and medicine, surveys show. And even some prominent public health experts were critical of the agencies’ Covid missteps and muddled messaging on masks and testing.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Wyoming’s Abortion Bans Are Unconstitutional, Judge Rules

    The ruling found that two state laws — one barring use of abortion pills, and one banning all forms of abortion — violated the state Constitution’s “fundamental right to make health care decisions.” A Wyoming judge ruled on Monday that two state abortion bans — including the first state law specifically banning the use of pills for abortion — violated the Wyoming Constitution and could not be enforced.Judge Melissa Owens of Teton County District Court wrote in her ruling that both the ban on medication abortion and a broader ban against all methods of abortion “impede the fundamental right to make health care decisions for an entire class of people, pregnant women.” She added, “The abortion statutes suspend a woman’s right to make her own health care decisions during the entire term of a pregnancy and are not reasonable or necessary to protect the health and general welfare of the people.”Enforcement of the two abortion bans, passed last year, had been temporarily halted by Judge Owens while the court case proceeded. Her decision on Monday blocks the laws permanently, although the state is expected to appeal. Efforts to reach the state attorney general’s office and the governor’s office were unsuccessful on Monday night.The suit to block the bans was filed by a group of plaintiffs that included two abortion providers in Wyoming; an obstetrician-gynecologist who often treats high-risk pregnancies; an emergency-room nurse; a fund that gives financing to abortion patients; and a woman who said her Jewish faith required access to abortion if a pregnant woman’s physical or mental health or life was in danger.An amendment to the Wyoming Constitution, approved by an overwhelming majority of the state’s voters in 2012, guarantees adults the right to make their own health care decisions.In court last year, the state, represented by Jay Jerde, a special assistant attorney general for Wyoming, argued that even though doctors and other health providers must be involved in abortions, there were many instances in which abortion was not “health care” because “it’s not restoring the woman’s body from pain, physical disease or sickness.”Mr. Jerde also argued that the constitutional amendment allowing people to make decisions about their own health care did not apply to abortion because terminating a pregnancy affected not just the woman making the decision, but the fetus as well.Judge Owens rejected both of those arguments. She wrote: “The uncontested facts establish that the abortion statutes fail to accomplish any of the asserted interests by the state. The state did not present any evidence refuting or challenging the extensive medical testimony presented by the plaintiffs.”Dr. Giovannina Anthony, an obstetrician-gynecologist and abortion provider who was one of the plaintiffs in the case, said on Monday night that she was “grateful and relieved that the judge agreed that abortion is health care and that abortion bans violate the rights of pregnant women.”Dr. Anthony said she expected the state to appeal. “This is not the end of the fight in Wyoming, but for now we can continue to provide evidence-based care without fear of a prison sentence.” More

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    Heart-Valve Patients Should Have Earlier Surgery, Study Suggests

    The results of a new clinical trial have overturned the “wait and see” approach that cardiologists have long favored for symptom-free patients.For decades, people with failing heart valves who nevertheless felt all right would walk out of the cardiologist’s office with the same “wait and see” treatment plan: Come back in six or 12 months. No reason to go under the knife just yet.A new clinical trial has overturned that thinking, suggesting that those patients would be much better off having their valves replaced right away with a minimally invasive procedure.The trial, whose results were published this week in The New England Journal of Medicine, could change the way doctors treat severe aortic stenosis, a narrowing of the valve that controls blood flow from the heart. The disease, which has a prognosis worse than that of most cancers, afflicts more than 3 percent of people ages 65 and older. It is expected to become more common as people live longer.Replacing people’s heart valves, even if they were not yet experiencing any ill effects, appeared to roughly halve their risk of being unexpectedly hospitalized for heart problems over at least two years, the trial found.Patients who were put on the more conservative treatment plan overwhelmingly ended up needing surgery anyway: Roughly 70 percent of them developed symptoms and needed to have their valves replaced within two years, suggesting that the disease worsens more quickly than previously understood.“You may be able to at least prevent that progression and perhaps improve patient outcomes by treating earlier,” said Dr. Gregg Stone, a professor of medicine at the Icahn School of Medicine at Mount Sinai, describing the implications of the trial. The findings, he said, “will have a major effect on practice.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    U.S. Study on Puberty Blockers Goes Unpublished Because of Politics, Doctor Says

    The leader of the long-running study said that the drugs did not improve mental health in children with gender distress and that the finding might be weaponized by opponents of the care.An influential doctor and advocate of adolescent gender treatments said she had not published a long-awaited study of puberty-blocking drugs because of the charged American political environment.The doctor, Johanna Olson-Kennedy, began the study in 2015 as part of a broader, multimillion-dollar federal project on transgender youth. She and colleagues recruited 95 children from across the country and gave them puberty blockers, which stave off the permanent physical changes — like breasts or a deepening voice — that could exacerbate their gender distress, known as dysphoria.The researchers followed the children for two years to see if the treatments improved their mental health. An older Dutch study had found that puberty blockers improved well-being, results that inspired clinics around the world to regularly prescribe the medications as part of what is now called gender-affirming care.But the American trial did not find a similar trend, Dr. Olson-Kennedy said in a wide-ranging interview. Puberty blockers did not lead to mental health improvements, she said, most likely because the children were already doing well when the study began.“They’re in really good shape when they come in, and they’re in really good shape after two years,” said Dr. Olson-Kennedy, who runs the country’s largest youth gender clinic at the Children’s Hospital of Los Angeles.That conclusion seemed to contradict an earlier description of the group, in which Dr. Olson-Kennedy and her colleagues noted that one quarter of the adolescents were depressed or suicidal before treatment.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Trump propuso que la fertilización in vitro fuera gratuita. ¿Es posible?

    Conseguir que se cubran los costosos tratamientos de fertilidad sería algo que no puede hacer un presidente solo, dijeron los expertos en políticas de salud.[Estamos en WhatsApp. Empieza a seguirnos ahora]El expresidente Donald Trump dijo el jueves en campaña que quiere que el tratamiento de fertilización in vitro (FIV) sea gratuito para todos los estadounidenses.“Bajo un gobierno de Trump, tu gobierno pagará o tu compañía de seguros estará obligada a pagar todos los costos asociados con el tratamiento de fertilización in vitro”, dijo Trump el jueves en un mitin en Potterville, Míchigan.La fecundación in vitro suele costar decenas de miles de dólares. Las políticas para cubrir esos costos serían difíciles de implementar, dijeron los expertos.Exigir a las aseguradoras que paguen estos procedimientos probablemente significaría aprobar leyes en el Congreso o persuadir a un panel de expertos para que añadan la FIV a una lista de servicios preventivos gratuitos de salud femenina establecidos por la Ley de Asistencia Asequible, la ley de cobertura de salud que Trump trató de derogar.Si el gobierno pagara directamente la FIV, se crearía un sistema de pagador único para una sola condición. El enfoque requeriría que el Congreso financie una nueva división del gobierno federal para supervisar el programa.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More