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    Real Risk to Youth Mental Health Is ‘Addictive Use,’ Not Screen Time Alone, Study Finds

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    Researchers found children with highly addictive use of phones, video games or social media were two to three times as likely to have thoughts of suicide or to harm themselves.As Americans scramble to respond to rising rates of suicidal behavior among youth, many policymakers have locked in on an alarming metric: the number of hours a day that American children spend glued to a glowing screen.But a study published on Wednesday in the medical journal JAMA, which followed more than 4,000 children across the country, arrived at a surprising conclusion: Longer screen time at age 10 was not associated with higher rates of suicidal behavior four years later.Instead, the authors found, the children at higher risk for suicidal behaviors were those who told researchers their use of technology had become “addictive” — that they had trouble putting it down, or felt the need to use it more and more. Some children exhibited addictive behavior even if their screen time was relatively low, they said.The researchers found addictive behavior to be very common among children — especially in their use of mobile phones, where nearly half had high addictive use. By age 14, children with high or increasing addictive behavior were two to three times as likely as other children to have thoughts of suicide or to harm themselves, the study found.“This is the first study to identify that addictive use is important, and is actually the root cause, instead of time,” said Yunyu Xiao, an assistant professor of psychiatry and population health sciences at Weill Cornell Medical College and the study’s lead author.Addictive behavior may be more difficult to control during childhood, before the prefrontal cortex, which acts as a brake on impulsivity, is fully developed.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Gun Deaths of Children Rose in States That Loosened Gun Laws, Study Finds

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      Researchers looked at firearm fatalities in the 13 years immediately after the Supreme Court limited local governments’ ability to restrict gun ownership.Firearm deaths of children and teenagers rose significantly in states that enacted more permissive gun laws after the Supreme Court in 2010 limited local governments’ ability to restrict gun ownership, a new study has found.In states that maintained stricter laws, firearm deaths were stable after the ruling, the researchers reported, and in some, they even declined.Guns are the leading cause of death in the United States for people under 18. Dr. Jeremy Faust, an emergency room doctor at Massachusetts General Brigham Hospital in Boston, who was the study’s lead author, said he was dismayed to find that most of the children’s deaths were homicides and suicides.“It’s surprising how few of these are accidents,” Dr. Faust said. “I always thought that a lot of pediatric mortality from guns is that somebody got into the wrong place, and I still think safe storage is important, but it’s mostly homicides and suicides.”John Commerford, executive director of the NRA Institute for Legislative Action, called the study “political propaganda masquerading as scientific research.”The study, published Monday in JAMA Pediatrics, examined the 13-year period after the June 2010 Supreme Court ruling that the Second Amendment, which protects an individual’s right to bear arms, applies to state and local gun-control laws. The decision effectively limited the ability of state and local governments to regulate firearms.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Four States Ask F.D.A. to Lift Special Restrictions on Abortion Pill

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      The states consider it a move to force the F.D.A. to review and acknowledge extensive research showing the pill’s safety.In a strategy aimed at countering efforts to further restrict the abortion pill mifepristone, attorneys general of four states that support abortion rights on Thursday asked the Food and Drug Administration to do the opposite and lift the most stringent remaining restrictions on the pill.The petition filed by Massachusetts, New York, California and New Jersey might seem surprising given the opposition to abortion expressed by Trump administration officials. But the attorneys general consider it a move that would require the F.D.A. to acknowledge extensive scientific research that has consistently found mifepristone safe and effective, said an official with the Massachusetts attorney general’s office who worked on the filing and asked not to be named in order to share background information. It would also prevent the F.D.A. from changing mifepristone regulations while the petition is pending.The petition notes that at a May senate hearing, Robert F. Kennedy Jr., the health and human services secretary, responded to questions by Senator Josh Hawley, Republican of Missouri, who opposes abortion, by saying he had ordered the F.D.A. to do a “complete review” of mifepristone.“We want to make sure that when F.D.A. is making these decisions that they have all the data in front of them, all of the really powerful data that show that mifepristone is safe” the Massachusetts official said.The F.D.A. is required to respond within 180 days by granting or denying the request, or saying it needs more time. In its responses, the agency must document its position, which could be useful in lawsuits, including one that the four states could file if their petition is denied.Mifepristone, which blocks a hormone necessary for pregnancy development, was approved for abortion in America in 2000. The F.D.A. imposed an additional regulatory framework called Risk Evaluation and Mitigation Strategy, or REMS, on mifepristone. That framework has been used for only about 300 drugs, currently covering only about 60 medications.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Trump Budget Eliminates Funding for Crucial Global Vaccination Programs

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      The spending proposal terminates support of health programs that, according to the proposal, “do not make Americans safer.”The Trump administration’s proposed budget for the coming fiscal year eliminates funding for programs that provide lifesaving vaccines around the world, including immunizations for polio.The budget, submitted to Congress last week, proposes to eliminate the Centers for Disease Control and Prevention’s global health unit, effectively shutting down its $230 million immunization program: $180 million for polio eradication and the rest for measles and other vaccine-preventable diseases. The budget plan also withdraws financial support for Gavi, the international vaccine alliance that purchases vaccines for children in developing countries.Overall, the budget request explicitly follows President Trump’s America First policy, slashing funds for global health programs that fight H.I.V. and malaria, and cutting support altogether to fight diseases that affect only poorer countries.“The request eliminates funding for programs that do not make Americans safer, such as family planning and reproductive health, neglected tropical diseases, and nonemergency nutrition,” the proposal said.Many public health experts said that such thinking is flawed because infectious diseases routinely breach borders. The United States is battling multiple measles outbreaks, prompting the C.D.C. last week to warn travelers about the risks of contracting measles. Each of those outbreaks began with a case of measles contracted by an international traveler.“Every single measles case this year is related to actual importations of the virus into the United States,” said Dr. Walter Orenstein, associate director of the Emory Vaccine Center and a former director of the United States’ Immunization Program.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Trump Administration Ends Program Critical to Search for an H.I.V. Vaccine

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      The termination is the latest in a series of cuts to H.I.V. research and programs to prevent the disease.The Trump administration has dealt a sharp blow to work on H.I.V. vaccines, terminating a $258 million program whose work was instrumental to the search for a vaccine.Officials from the H.I.V. division of the National Institutes of Health delivered the news on Friday to the program’s two leaders, at Duke University and the Scripps Research Institute.Both teams were collaborating with numerous other research partners. The work was broadly applicable to a wide range of treatments for other illnesses, from Covid drugs to snake antivenom and therapies for autoimmune diseases.“The consortia for H.I.V./AIDS vaccine development and immunology was reviewed by N.I.H. leadership, which does not support it moving forward,” said a senior official at the agency who was not authorized to speak on the matter and asked not to be identified.“N.I.H. expects to be shifting its focus toward using currently available approaches to eliminate H.I.V./AIDS,” the official said.The program’s elimination is the latest in a series of cuts to H.I.V.-related initiatives, and to prevention of the disease in particular. Separately, the N.I.H. also paused funding for a clinical trial of an H.I.V. vaccine made by Moderna.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      A Blood Test for Alzheimer’s: What to Know

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      The test may make it easier to identify whether people with memory and thinking problems have Alzheimer’s or not.A blood test that can help diagnose Alzheimer’s disease has received clearance from the Food and Drug Administration. This is a step toward a goal of scientists and doctors to one day be able to diagnose a confounding illness with the prick of a finger. But there is still a long way to go.Here is what to know:What is the test, and how should it be used?The test, manufactured by Fujirebio Diagnostics, is intended to be used only by specialists in Alzheimer’s, the F.D.A. said. Its mouthful of a name — Lumipulse G pTau217/ß-Amyloid 1-42 Plasma Ratio — describes what the test measures: levels of two proteins, amyloid and tau, that are hallmarks of Alzheimer’s disease.In people who develop Alzheimer’s, amyloid begins to accumulate and form plaques in the brain more than 20 years before any symptoms of cognitive impairment. Tau accumulates later, forming tangles in the brain, and is much more closely correlated with cognitive decline.Can people who don’t have memory problems take the blood test?No. The F.D.A., and Alzheimer’s experts, emphasized that the blood test should be given only to people who are already experiencing cognitive decline and are ages 55 and older. Moreover, it should not be used on its own to diagnose or to rule out Alzheimer’s.“Other clinical evaluations or additional tests should be used for determining treatment options,” the F.D.A. said in a statement, adding that “the results must be interpreted in conjunction with other patient clinical information.”The current gold standard for diagnosing Alzheimer’s still involves either imaging using PET scans, which are expensive, or spinal taps, which are invasive. The blood test can help flag the presence of the Alzheimer’s-related proteins, and doctors might then order confirmatory testing with one of the other methods.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      What a Prostate Cancer Diagnosis Like Biden’s Means for Patients

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      While prognoses for prostate cancer patients were once measured in months, experts say that advances in treatment and diagnosis now improve survival by years.Prostate cancer experts say that former President Joseph R. Biden’s diagnosis is serious. Announced on Sunday by his office, the cancer has spread to his bones. And it is Stage 4, the most deadly of stages for the illness. It cannot be cured.But the good news, prostate cancer specialists said, is that recent advances in diagnosing and treating prostate cancer — based in large part on research sponsored by the National Institutes of Health and the Defense Department — have changed what was once an exceedingly grim picture for men with advanced disease.“Life is measured in years now, not months,” said Dr. Daniel W. Lin, a prostate cancer specialist at the University of Washington.Dr. Judd Moul, a prostate cancer expert at Duke University, said that men whose prostate cancer has spread to their bones, “can live 5, 7, 10 or more years” with current treatments. A man like Mr. Biden, in his 80s, “could hopefully pass away from natural causes and not from prostate cancer,” he said.Mr. Biden’s office said the former president had urinary symptoms, which led him to seek medical attention.But, Dr. Lin said, “I highly doubt his symptoms were due to cancer.”Instead, he said, the most likely scenario is that a doctor did an exam, noticed a nodule on Mr. Biden’s prostate and did a blood test, the prostate-specific antigen test. The PSA test looks for a protein released by cancer cells, and can be followed up by an M.R.I. The blood test and the M.R.I. would have pointed to the cancer.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Surgeons Perform First Human Bladder Transplant

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      Surgeons in Southern California have performed the first human bladder transplant, introducing a new, potentially life-changing procedure for people with debilitating bladder conditions.The operation was performed earlier this month by a pair of surgeons from the University of California, Los Angeles, and the University of Southern California on a 41-year-old man who had lost much of his bladder capacity from treatments for a rare form of bladder cancer.“I was a ticking time bomb,” the patient, Oscar Larrainzar, said on Thursday during a follow-up appointment with his doctors. “But now I have hope.”The doctors plan to perform bladder transplants in four more patients as part of a clinical trial to get a sense of outcomes like bladder capacity and graft complications before pursuing a larger trial to expand its use.Dr. Inderbir Gill, who performed the surgery along with Dr. Nima Nassiri, called it “the realization of a dream” for treating thousands of patients with crippling pelvic pain, inflammation and recurrent infections.“There is no question: A potential door has been opened for these people that did not exist earlier,” said Dr. Gill, the chairman of the urology department at U.S.C.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Drug Overdose Deaths Plummeted in 2024, C.D.C. Reports

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      The progress comes as the Trump administration is proposing to cut funding for many programs believed to have contributed to the improvement.Overdose deaths in the United States fell by nearly 30,000 last year, the government reported on Wednesday, the strongest sign yet that the country is making progress against one of its deadliest, most intractable public health crises.The data, released by the Centers for Disease Control and Prevention, is the latest in a series of reports over the past year offering hints that the drug-related death toll that has gutted families and communities could be starting to ease.Public health experts had been carefully watching the monthly updates, with skepticism at first, and then with growing hope. Wednesday’s report was the most encouraging yet. Deaths declined in all major categories of drug use, stimulants as well as opioids, dropping in every state but two. Nationwide, drug fatalities plunged nearly 27 percent.“This is a decline that we’ve been waiting more than a decade for,” said Dr. Matthew Christiansen, a physician and former director of West Virginia’s drug control policy. “We’ve invested hundreds of billions of dollars into addiction.”Addiction specialists said that changes in the illicit drug supply as well as greater access to drug treatment and the use of naloxone to reverse overdoses seemed to be playing a role, but whether the country could sustain that progress was an open question.In announcing the new numbers, the C.D.C. praised President Trump, saying in a statement that since he “declared the opioid crisis a public health emergency in 2017” the government had added more resources to battle the drug problem.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More