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    Time to Say Goodbye to the B.M.I.?

    The body mass index has long been criticized as a flawed indicator of health. A replacement has been gaining support: the body roundness index.Move over, body mass index. Make room for roundness — to be precise, the body roundness index.The body mass index, or B.M.I., is a ratio of height to weight that has long been used as a medical screening tool. It is one of the most widely used health metrics but also one of the most reviled, because it is used to label people overweight, obese or extremely obese.The classifications have been questioned by athletes like the American Olympic rugby player Ilona Maher, whose B.M.I. of 30 technically puts her on the cusp of obesity. “But alas,” she said on Instagram, addressing online trolls who tried to shame her about her weight, “I’m going to the Olympics and you’re not.”Advocates for overweight individuals and people of color note that the formula was developed nearly 200 years ago and based exclusively on data from men, most of them white, and that it was never intended for medical screening. Even physicians have weighed in on the shortcomings of B.M.I. The American Medical Association warned last year that B.M.I. is an imperfect metric that doesn’t account for racial, ethnic, age, sex and gender diversity. It can’t differentiate between individuals who carry a lot of muscle and those with fat in all the wrong places.“Based on B.M.I., Arnold Schwarzenegger when he was a bodybuilder would have been categorized as obese and needing to lose weight,” said Dr. Wajahat Mehal, director of the Metabolic Health and Weight Loss Program at Yale University.“But as soon as you measured his waist, you’d see, ‘Oh, it’s 32 inches.’”So welcome a new metric: the body roundness index. B.R.I. is just what it sounds like — a measure of how round or circlelike you are, using a formula that takes into account height and waist, but not weight.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Trump propuso que la fertilización in vitro fuera gratuita. ¿Es posible?

    Conseguir que se cubran los costosos tratamientos de fertilidad sería algo que no puede hacer un presidente solo, dijeron los expertos en políticas de salud.[Estamos en WhatsApp. Empieza a seguirnos ahora]El expresidente Donald Trump dijo el jueves en campaña que quiere que el tratamiento de fertilización in vitro (FIV) sea gratuito para todos los estadounidenses.“Bajo un gobierno de Trump, tu gobierno pagará o tu compañía de seguros estará obligada a pagar todos los costos asociados con el tratamiento de fertilización in vitro”, dijo Trump el jueves en un mitin en Potterville, Míchigan.La fecundación in vitro suele costar decenas de miles de dólares. Las políticas para cubrir esos costos serían difíciles de implementar, dijeron los expertos.Exigir a las aseguradoras que paguen estos procedimientos probablemente significaría aprobar leyes en el Congreso o persuadir a un panel de expertos para que añadan la FIV a una lista de servicios preventivos gratuitos de salud femenina establecidos por la Ley de Asistencia Asequible, la ley de cobertura de salud que Trump trató de derogar.Si el gobierno pagara directamente la FIV, se crearía un sistema de pagador único para una sola condición. El enfoque requeriría que el Congreso financie una nueva división del gobierno federal para supervisar el programa.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Fossils Show Giant Predatory Sea Scorpions Were Distance Swimmers

    Specimens of what appear to be the largest eurypterid species found in Australia could shed light on the sudden extinction of the massive arthropods.Most modern scorpions would fit in the palm of your hand. But in the oceans of the Paleozoic era more than 400 million years ago, animals known popularly as sea scorpions were apex predators that could grow larger than people in size.“They were effectively functioning as sharks,” said Russell Bicknell, a paleobiologist at the American Museum of Natural History.New research by Dr. Bicknell and colleagues, published Saturday in the journal Gondwana Research and relying on Australian fossils, reveals that the biggest sea scorpions were capable of crossing oceans, a finding that is “absolutely pushing the limits of what we know arthropods could do,” he said.What are commonly known as sea scorpions were a diverse group of arthropods called eurypterids. They came in many shapes and sizes but are perhaps best known for their largest representatives, which could grow to more than nine feet long. With huge claws, a beefy exoskeleton and a strong set of legs for swimming, the larger sea scorpions most likely ruled the seas.However fearsome these arthropods must have been to Paleozoic prey, they went extinct without much of a bang. The fossil record of eurypterids peaked in the Silurian period, which started about 444 million years ago, and they then abruptly died out after the early Devonian period ended about 393 million years ago.That sudden turn of fate has left scientists bewildered.“They appear, they start doing really well, they get very big, and then they go extinct,” said James Lamsdell, a paleobiologist at West Virginia University who was not involved in the study. “For a while they were so dominant, and then they just burned out.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    For Stonehenge’s Altar Stone, an Improbably Long Ancient Journey

    A six-ton megalith at the heart of the archaeological site traveled more than 450 miles to get there, a new study concludes.Near the center of the roughly 5,000-year-old circular monument known as Stonehenge is a six-ton, rectangular chunk of red sandstone. In Arthurian legend, the so-called Altar Stone was part of the ring of giant rocks that the wizard Merlin magically transported from Mount Killaurus, in Ireland, to Salisbury Plain, a chalk plateau in southern England — a journey chronicled around 1136 by a Welsh cleric, Geoffrey of Monmouth, in his “Historia Regum Britanniae.”Since then, the accepted provenance of the Altar Stone has shifted, spanning a range of possible sites from east Wales and the Marches to northern England. On Wednesday, a study in the journal Nature reroutes the megalith’s odyssey more definitively, proposing a path much longer than scientists had thought possible.The researchers analyzed the chemical composition and the ages of mineral grains in two microscopic fragments of the Altar Stone. This pinpointed the stone’s source to the Orcadian Basin in northeast Scotland, an area that spans Inverness, the Orkney Islands and Shetland. To reach the archaeological site in Wiltshire, the megalith would have traveled at least 465 miles by land or more than 620 miles along the present-day coastline if it came by sea.“This is a genuinely shocking result,” said Rob Ixer, a retired mineralogist and research fellow at University College London who collaborated on the project. “The work prompts two important questions: How and why did the stone travel the length of Britain?”Stonehenge features two kinds of rocks: larger sarsens and smaller bluestones. The sarsens are sandstone slabs found naturally in southern England. They weigh 20 tons on average and were erected in two concentric arrangements. The inner ring is a horseshoe of five trilithons (two uprights capped by a horizontal lintel), of which three complete ones still stand.Richard Bevins examining Bluestone Stone 46, a rhyolite most probably from north Pembrokeshire, on Wales’s southwest coast.Nick Pearce/Aberystwyth University.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    A Blood Test Accurately Diagnosed Alzheimer’s 90% of the Time, Study Finds

    It was much more accurate than primary care doctors using cognitive tests and CT scans. The findings could speed the quest for an affordable and accessible way to diagnose patients with memory problems.Scientists have made another major stride toward the long-sought goal of diagnosing Alzheimer’s disease with a simple blood test. On Sunday, a team of researchers reported that a blood test was significantly more accurate than doctors’ interpretation of cognitive tests and CT scans in signaling the condition.The study, published Sunday in the journal JAMA, found that about 90 percent of the time the blood test correctly identified whether patients with memory problems had Alzheimer’s. Dementia specialists using standard methods that did not include expensive PET scans or invasive spinal taps were accurate 73 percent of the time, while primary care doctors using those methods got it right only 61 percent of the time.“Not too long ago measuring pathology in the brain of a living human was considered just impossible,” said Dr. Jason Karlawish, a co-director of the Penn Memory Center at the University of Pennsylvania who was not involved in the research. “This study adds to the revolution that has occurred in our ability to measure what’s going on in the brain of living humans.”The results, presented Sunday at the Alzheimer’s Association International Conference in Philadelphia, are the latest milestone in the search for affordable and accessible ways to diagnose Alzheimer’s, a disease that afflicts nearly seven million Americans and over 32 million people worldwide. Medical experts say the findings bring the field closer to a day when people might receive routine blood tests for cognitive impairment as part of primary care checkups, similar to the way they receive cholesterol tests.“Now, we screen people with mammograms and PSA or prostate exams and other things to look for very early signs of cancer,” said Dr. Adam Boxer, a neurologist at the University of California, San Francisco, who was not involved in the study. “And I think we’re going to be doing the same thing for Alzheimer’s disease and hopefully other forms of neurodegeneration.”In recent years, several blood tests have been developed for Alzheimer’s. They are currently used mostly to screen participants in clinical trials and by some specialists like Dr. Boxer to help pinpoint if a patient’s dementia is caused by Alzheimer’s or another condition.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Moving In Childhood Contributes to Depression, Study Finds

    A study of more than a million Danes found that frequent moves in childhood had a bigger effect than poverty on adult mental health risk.In recent decades, mental health providers began screening for “adverse childhood experiences” — generally defined as abuse, neglect, violence, family dissolution and poverty — as risk factors for later disorders.But what if other things are just as damaging?Researchers who conducted a large study of adults in Denmark, published on Wednesday in the journal JAMA Psychiatry, found something they had not expected: Adults who moved frequently in childhood have significantly more risk of suffering from depression than their counterparts who stayed put in a community.In fact, the risk of moving frequently in childhood was significantly greater than the risk of living in a poor neighborhood, said Clive Sabel, a professor at the University of Plymouth and the paper’s lead author.“Even if you came from the most income-deprived communities, not moving — being a ‘stayer’ — was protective for your health,” said Dr. Sabel, a geographer who studies the effect of environment on disease.“I’ll flip it around by saying, even if you come from a rich neighborhood, but you moved more than once, that your chances of depression were higher than if you hadn’t moved and come from the poorest quantile neighborhoods,” he added.The study, a collaboration by Aarhus University, the University of Manchester and the University of Plymouth, included all Danes born between 1982 and 2003, more than a million people. Of those, 35,098, or around 2.3 percent, received diagnoses of depression from a psychiatric hospital.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Melodies of Popular Songs Have Gotten Simpler Over Time

    “Well, we’re all in the mood for a melody,” Billy Joel crooned in “Piano Man,” his iconic 1973 barroom ballad. That may have been true enough when Mr. Joel wore a younger man’s clothes, but a new study conducted by computational musicologists at Queen Mary University of London has found that vocal melodies in popular music have become much less complex over time.The study, published on Thursday in the journal Scientific Reports, used mathematical models and algorithms to pinpoint three “melodic revolutions” — in 1975, 1996 and 2000 — that brought increasing simplicity to the two main components of melody: rhythm, or the pattern of sounds and silences in a piece of music, and pitch, the measure of how high or low the notes are.The study looked at the top five Billboard songs every year from 1950 to 2023. Both rhythm and pitch became steadily less complex over that period, the study found. “Conservatively, they have both decreased by 30 percent,” said Madeline Hamilton, a graduate student at Queen Mary University of London who led the research.The 1975 hit “Love Will Keep Us Together” by Captain & Tennille contains a lot of unexpected notes and rhythmic complexity.“Breathe” by Faith Hill, the top song of 2000, has no accidentals, lots of repetition and straightforward rhythms.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Gilead Shot Provides Total Protection From HIV in Trial of Young African Women

    An injection given just twice a year could herald a breakthrough in protecting the population that has the highest infection rates.Researchers and activists in the trenches of the long fight against H.I.V. got a rare piece of exciting news this week: Results from a large clinical trial in Africa showed that a twice-yearly injection of a new antiviral drug gave young women total protection from the virus.“I got cold shivers,” said Dr. Linda-Gail Bekker, an investigator in the trial of the drug, lenacapavir, describing the startling sight of a line of zeros in the data column for new infections. “After all our years of sadness, particularly over vaccines, this truly is surreal.”Yvette Raphael, the leader of a group called Advocacy for Prevention of H.I.V. and AIDS in South Africa, said it was “the best news ever.”The randomized controlled trial, called Purpose 1, was conducted in Uganda and South Africa. It tested whether the every-six-months injection of lenacapavir, made by Gilead Sciences, would provide better protection against H.I.V. infection than two other drugs in wide use in high-income countries, both daily pills.The results were so convincing that the trial was halted early at the recommendation of the independent data review committee, which said all participants should be offered the injection because it clearly provided superior protection against the virus.None of the 2,134 women in the arm of the trial who received lenacapavir contracted H.I.V. By comparison, 16 of the 1,068 women (or 1.5 percent) who took Truvada, a daily pill that has been available for more than a decade, and 39 of 2,136 women (1.8 percent) who received a newer daily pill called Descovy were infected.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More