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    Akira Endo, Scholar of Statins That Reduce Heart Disease, Dies at 90

    The Japanese biochemist found in the 1970s that cholesterol-lowering drugs lowered the LDL, or “bad” cholesterol, level in the blood.Akira Endo, a Japanese biochemist whose research on fungi helped to lay the groundwork for widely prescribed drugs that lower a type of cholesterol that contributes to heart disease, died on June 5. He was 90.Chiba Kazuhiro, the president of Tokyo University of Agriculture and Technology, where Dr. Endo was a professor emeritus, confirmed the death in a statement. The statement did not give a cause or say where he died.Cholesterol, mostly made in the liver, has important functions in the body. It is also a major contributor to coronary artery disease, a leading cause of death in the United States, Japan and many other countries.In the early 1970s, Dr. Endo grew fungi in an effort to find a natural substance that could block a crucial enzyme that is part of the production of cholesterol. Some scientists worried that doing so might threaten cholesterol’s positive functions.But by 1980, Dr. Endo’s team had found that a cholesterol-lowering drug, or statin, lowered the LDL, or “bad” cholesterol level, in the blood. And by 1987, after other researchers in the field had published additional research on statins, Merck was manufacturing the first licensed statin.Such drugs have proven effective in reducing the risk for cardiovascular disease, and millions of people in the United States and beyond now take them for high levels of LDL.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Houthis Attack Merchant Ship in Red Sea Off Yemen’s Coast

    Yemen’s Houthi rebels attacked a merchant ship in the Red Sea on Wednesday in the latest escalation of the Iran-backed militia’s campaign against shipping in support of Palestinians in the Gaza Strip.A British government maritime agency said the vessel was “hit on the stern by a small craft” about 66 nautical miles southwest of the Houthi-held port of Hodeida in Yemen.After the attack, the ship was “taking on water, and not under command of the crew,” the agency, The United Kingdom Maritime Trade Operations, said in a statement on its website. The statement said the ship’s master had reported it was also “hit for a second time by an unknown airborne projectile.”A Houthi military spokesman, Yahya Saree, said in a televised speech that the group had used unmanned surface boats, a number of drones and ballistic missiles to target the ship, which he identified as the Tutor, a Greek-owned bulk carrier. He claimed the ship was seriously damaged and could sink.On Wednesday, the Houthis said they launched two joint military operations with the Islamic Resistance in Iraq, on the Israeli cities Ashdod and Haifa, a claim Israel denied.Since November, the Houthis have launched dozens of attacks on ships in the vital sea route in the Red Sea and Gulf of Aden, stifling global maritime trade.In retaliation, the U.S. and British navies have been intensifying airstrikes against Houthi targets, the latest coming on June 7 after the rebel group detained 11 United Nations employees in Yemen.The U.S. Central Command said its forces had destroyed four aerial drones and two anti-ship missiles in Houthi-controlled areas of Yemen last Friday, as well as a Houthi patrol boat in the Red Sea.In February, American military officials said the United States struck five Houthi military targets, including an undersea drone they described as an “unmanned underwater vessel” that they believed the Houthis could have received from Iran. More

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    NYT Crossword Answers for June 13, 2024

    Kevin Curry offers a different read on things.Jump to: Today’s Theme | Tricky CluesTHURSDAY PUZZLE — I’ve developed a Pavlovian association with Thursday crosswords such that, if I so much as glance at the empty puzzle, my hackles go up. I solve as though I were a detective in the parlor scene of a murder mystery — there’s a dastardly theme in here somewhere, and every clue is a suspect.Kevin Curry was kind enough to relieve us of such sleuthing by making it clear where his themed clues lay in today’s crossword (they’re in all caps). It’s still a Thursday challenge, to be sure, but I believe we can solve it together.Today’s ThemeMr. Curry has concealed a series of idioms in this grid, representing them using capitalized clues and parentheses around certain letters. The trick is to read the letters phonetically and then note their locations in the words. 15-Across, for instance, reads “EM(B)RACE.” This solves to B IN TOUCH — because it’s the letter B inside a word that means “touch.” 23-Across reads “ALMIGHT(Y),” which solves to Y IN GOD’S NAME.Other themed phrases use the word OF instead of IN to indicate the parenthesized letter’s placement: “TROP(I)CAL STORM” (39A) solves to I OF THE HURRICANE.Can’t place the remaining phrases? You can click to reveal them below.53A. “(C)OMPASSION”C OF HUMANITY We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Disney and DeSantis Reach Agreement, Ending Protracted Fight

    The deal locks in a 15-year expansion plan for Disney World and clears a path for Disney to restart political donations in Florida.Disney and Gov. Ron DeSantis of Florida have finally ended their feud, clearing the way for $17 billion in planned development at Walt Disney World near Orlando.On Wednesday night, the Central Florida Tourism Oversight District — an entity that Mr. DeSantis took over in 2022, ending 55 years of Disney control and sparking multiple lawsuits — gave the company a big part of what it wanted all along: a locked-in, long-term plan for expanding Disney World. At least for the next 15 years, the length of the new agreement, Disney can develop the resort without worrying about interference by Florida politicians.Put bluntly, state leaders can no longer use growth at the 25,000-acre resort as a political weapon, as Mr. DeSantis did two years ago after Disney said it would fight to repeal a state education law that opponents called anti-gay.Jeff Vahle, the president of Disney World, said in a statement that the agreement would support “the growth of this global destination, fueling the Florida economy.” It gives Disney the ability to build a fifth theme park, add three small parks, expand retail and office space and build 14,000 hotel rooms, for a resort total of nearly 54,000.Disney has earmarked $17 billion to expand the complex over the next decade, growth it has said will create an estimated 13,000 jobs.The district noted that, under the agreement, Disney is obligated to spend at least $8 billion. The company also must expand an affordable housing initiative and carry out a “buy local initiative,” with at least 50 percent of its total spending in expanding Disney World going to Florida businesses.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Western Governors Give Bipartisanship a Try. At Least for a Few Days.

    The bipartisan boat ride on Lake Tahoe was scrapped because of scheduling issues. At least three of the participating Republicans were suing the administration of one of the Democrats.At the opening reception, Gov. Mark Gordon of Wyoming, a conservative in cowboy boots, turned to Gov. Gavin Newsom of California, a liberal in sunglasses and a ball cap, and joked, “You and I shouldn’t be seen together.”Not everybody laughed.As the Western Governors’ Association marked its 40th anniversary this week in Olympic Valley, Calif., the organization did its best to maintain a tradition that has long been its hallmark: the increasingly lost art of governing across party lines.Under sunny skies and a snowcapped Sierra Nevada, experts from the private sector to members of the Biden administration presented on disaster management, opioids and carbon capture. Aides rushed between meeting rooms. Eight governors appeared on a panel examining the organization’s longstanding culture of consensus — but seven of them were no longer in office.“We used to have this bumper sticker — ‘Bipartisanship Happens,’” Steve Bullock, the former Democratic governor of Montana, said. “But bipartisanship doesn’t just happen. It takes work.”Mr. Newsom welcomed the 300 or so attendees to the meeting, but he did not stay for the full conference.Jim Wilson/The New York TimesWe are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Hunter Biden Is Expected to Appeal Conviction on Gun Charges

    Lawyers for Mr. Biden are considering a number of challenges to the guilty verdict, including one based on the Second Amendment.Hunter Biden is expected to appeal his felony conviction for falsifying a federal firearms application, likely arguing that the judge in the case violated his constitutional rights in her instructions to the jury, according to people in his orbit and legal experts.Mr. Biden’s lawyer Abbe Lowell has also signaled that any appeal would be based on the Supreme Court’s landmark decision in 2022 that vastly expanded gun rights, a ruling that spawned legal challenges to the part of the federal firearms form at the center of the Biden case. In Mr. Biden’s case, it included a question asking buyers about their drug use.Any appeal would be an uphill climb, and the lawyers representing President Biden’s son cannot officially file one until he is sentenced at the courthouse in Wilmington, Del., within 120 days, or about a month after he is scheduled to go on trial on federal tax charges in Los Angeles.There is still a possibility that David C. Weiss, the special counsel in the case, will seek a plea agreement before the tax trial begins, and would have leverage in negotiations now that Mr. Biden is already a convicted felon, according to former prosecutors. Mr. Biden might have greater incentive to reach a deal to avoid another public airing of his personal ordeal beyond what was presented in Wilmington last week.On Tuesday, after deliberating for a little more than three hours, a jury convicted Mr. Biden of three felony counts related to lying on a federal firearms application and illegally possessing a weapon.Mr. Lowell suggested that he might appeal, vowing to “vigorously pursue all the legal challenges available to Hunter.” President Biden said in a statement that he would “accept the outcome of this case and will continue to respect the judicial process as Hunter considers an appeal.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Christophe Deloire, Who Strove to Protect Journalists, Dies at 53

    As the leader and spokesman for Reporters Without Borders, he rescued some, sought refuge for others and lobbied for pluralism in the press.Christophe Deloire, whose nonpartisan organization to protect journalists rescued dissidents from jail and championed a diversity of viewpoints in the profession around the world, died on Saturday in Paris. He was 53.The cause was complications of brain cancer, according to Reporters Without Borders, the media group for which he served as secretary general for the last 12 years.Mr. Deloire, who was himself a journalist and an author, lobbied publicly and labored behind the scenes to promote a free press in countries that muzzled journalists. He helped negotiate freedom for those who had been threatened with arrest, imprisoned or held hostage.Marina Ovsyannikova, a former Russian state journalist who fled her country with the help of Reporters Without Borders, at the group’s offices in Paris in 2023.Dmitry Kostyukov for The New York TimesIn 2023, Reporters Without Borders, known by its French initials R.S.F., coordinated the clandestine escape of Marina Ovsyannikova, a former Russian state TV journalist who incensed the Kremlin by storming a live news program in 2022 to denounce the invasion of Ukraine.Ms. Ovsyannikova was fined and forced to choose between prison and exile. Then, after another public protest, she was placed under house arrest pending a trial. On her lawyers’ advice, she fled Russia with her 11-year-old daughter, evading the authorities by switching cars several times before trudging through mud to cross the border and make her way to France.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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    Senate Republicans Block Supreme Court Ethics Measure Pushed by Democrats

    Democrats made what they knew was a doomed attempt as they faced pressure from the left to do more to try to hold the court accountable.Senate Republicans on Wednesday blocked an effort by Democrats to quickly pass Supreme Court ethics and transparency legislation they had pushed forward in the wake of disclosures about justices taking unreported gifts and travel and other ethical issues surrounding the high court.The unsuccessful outcome was predetermined, but represented an effort by Senate Democrats to show they were pressing the case against the court. It was also aimed at demonstrating the limits of their power given the narrow divide in the Senate and deep Republican opposition to Congress taking action to impose stricter ethics rules on the justices.“The ethics crisis at the Supreme Court, the highest court in the land, is unacceptable,” Senator Richard J. Durbin, the Illinois Democrat who chairs the Judiciary Committee, said in calling for the measure to be approved. “It is unsustainable and it’s unworthy of the highest court in the land.”Republicans assailed the bill as a naked effort by Democrats to undercut the court because of ideological disagreements with its decisions, particularly with major rulings about to be handed down. They accused Democrats of trying to intimidate the justices.“Let’s be clear: This is not about improving the court, this is about undermining the court,” said Senator Lindsey Graham of South Carolina, the top Republican on the Judiciary Committee, who lodged the objection to taking up the bill. “This will be an unconstitutional overreach. This would undermine the court’s ability to operate effectively.”The move by Democrats came as progressives have been ramping up their demands for more aggressive action in the Senate.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More