Here’s what you need to know at the end of the day.(Want to get this newsletter in your inbox? Here’s the sign-up.)Good evening. Here’s the latest at the end of Wednesday.President Biden with military leaders in the White House Cabinet Room.Sarahbeth Maney/The New York Times1. Russia test-launched a new missile as its forces in Ukraine unleashed artillery and rocket strikes in the eastern Donbas region. President Vladimir Putin said the new intercontinental ballistic missile should cause anyone threatening Russia to “think twice.”The Russian Defense Ministry said the new missile could deploy nuclear warheads at hypersonic speeds anywhere in the world but it needed further testing before deployment.In Ukraine, the air force has bolstered its operations after receiving spare parts shipments coordinated by the U.S. But in the devastated city of Mariupol, citizens and soldiers sheltering in an abandoned steel plant may have only hours left before it falls. They vowed to fight until the “last drop of blood.” President Biden met top U.S. defense officials, a day after promising to send more artillery to help Ukraine. The U.N. Secretary General, António Guterres, requested to meet with the leaders of Russia and Ukraine to discuss “urgent steps to bring about peace.” Travelers heading to O’Hare Airport in Chicago yesterday.Jamie Kelter Davis for The New York Times2. The C.D.C. said a mask mandate for airplanes and other public transport “remains necessary for the public health.” It said it had asked the Justice Department to appeal the Florida judge’s ruling that struck down the federal mask requirement on planes, trains, buses and other modes of transportation. The debate over the mandates comes as a nationwide poll found that 56 percent of Americans still support masking on public transit, with only 24 percent opposed. Times reporters took a closer look at how Americans are responding to the confusion over guidelines. And Covid cases are up again in some areas: New York’s governor, Kathy Hochul, warned today of another spike driven by two new versions of the Omicron variant. In other Covid news, there are concerns about the alarming rise in chronic student absenteeism in the U.S., spurred by the pandemic. French President Emmanuel Macron and his opponent, Marine Le Pen, faced off tonight.Pool photo by Ludovic Marin3. President Emmanuel Macron and Marine Le Pen, the far-right leader, debated ahead of Sunday’s French presidential election. But what they said could matter less than how some voters feel about Macron: They hate him. A veteran political journalist called the level of loathing “unprecedented.” It stems, he thinks, from perceptions of Macron as an elitist. Le Pen herself takes every opportunity to remind voters of that as she campaigns. She referred at one rally to “words of a power without empathy.” The televised debate was crucial for Le Pen’s long quest to build her credibility and continue softening her image. Macron was under pressure to defend a five-year record tested by a series of social and economic crises. Though polls show that Macron holds the lead, it’s possible many French voters may simply stay home. The ranch in Sante Fe, N.M, where “Rust” was being filmed. Jae C. Hong/Associated Press4. New Mexico regulators faulted the producers of the movie “Rust” for the death of a cinematographer, Halyna Hutchins, who was shot during a scene in which the actor Alec Baldwin had to draw a gun. Hutchins was shot and killed on Oct. 21 when the gun, which was not supposed to be loaded with live ammunition, went off as Baldwin pointed it at the camera. Baldwin and other producers have been named in lawsuits seeking damages.New Mexico’s Occupational Health and Safety Bureau said that the film’s producers “knew that firearm safety procedures were not being followed on set and demonstrated plain indifference to employee safety.” The agency issued a $136,793 penalty, the maximum allowed..William Husel at his murder trial in Columbus, Ohio. Pool photo by Barbara Perenic5. A doctor in Ohio was acquitted of murdering his patients, who overdosed on fentanyl, the powerful opioid. The verdict, on 14 counts, brought an end to one of the state’s largest murder cases, which set off a debate about end-of-life medical care. The doctor, William Husel, was charged in 2019 after two hospital pharmacists raised concerns that he had been prescribing unusually high doses of fentanyl to gravely ill patients. Husel called it “comfort medication” to treat patients in severe pain. Prosecutors said he was abusing sick patients. Russia’s Daniil Medvedev during the 2021 Wimbledon tournament.Adrian Dennis/Agence France-Presse — Getty Images6. Wimbledon will bar Russian and Belarusian players from competing at this year’s tournament in London. What to Know About France’s Presidential ElectionCard 1 of 4Heading to a runoff. More