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    US lawmakers call on EPA to ban pesticide linked to Parkinson’s disease

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    More than 50 US lawmakers are calling on the Environmental Protection Agency (EPA) to join dozens of other countries in banning a widely used weedkiller linked to Parkinson’s disease and other health dangers.In a 31 October letter to the agency, seven US senators said that paraquat, a weedkiller commonly applied on US farms, was a “highly toxic pesticide whose continued use cannot be justified given its harms to farmworkers and rural communities”. The call for a ban from the senators came after 47 members of the US House of Representatives sent a similar letter to the EPA calling for a ban earlier in October.The lawmakers cite scientific links between paraquat use and development of Parkinson’s and other “life threatening diseases” as well as “grave impacts on the environment”. “Health risks include a higher risk of Parkinson’s disease, with some studies finding a 64% increase in the likelihood of developing Parkinson’s, non-Hodgkin’s Lymphoma, thyroid cancer, and other thyroid issues,” they wrote.The New Jersey senator Cory Booker, organizer of the Senate letter, said the risks of paraquat exposure were “well documented” and that it was “irresponsible” for the EPA to continue to allow its use. “I hope the EPA will follow the science and ban paraquat,” Booker said.The EPA has long maintained that there is no “clear link” between paraquat exposure and Parkinson’s disease, though the agency does have a number of restrictions on use of the chemical due to its acute toxicity. The agency issued a draft report earlier this year affirming its position.Still, the agency said at that time that it would be reviewing more scientific studies and would issue a final report by 17 January 2025.When asked about the congressional call for a ban, an EPA spokesperson said only that the agency “will respond to the letter appropriately”.Several California lawmakers pushed for a ban in the most recent state legislative session, also citing the risks of Parkinson’s. A compromise measure signed by the governor last month requires an expedited regulatory review of paraquat.The push to ban paraquat in the US was “long overdue”, said Ray Dorsey, a professor of neurology at the University of Rochester who studies the causes of Parkinson’s disease.“For 60 years, paraquat has been helping fuel the rise of Parkinson’s disease,” Dorsey said. “The evidence from human, laboratory and apparently even the company’s own research is overwhelming. When paraquat is banned, more lives will be spared the consequences of Parkinson’s.”Chinese-owned Syngenta, the longtime maker and marketer of paraquat products did not respond to a request for comment about the congressional letters. The company has denied there is any valid connection between Parkinson’s and paraquat. In response to previous reporting, it asserted that no “peer-reviewed scientific publication has established a causal connection between paraquat and Parkinson’s disease”.Internal Syngenta documents revealed by the Guardian show the company was aware many years ago of scientific evidence that paraquat could affect the brain in ways that cause Parkinson’s, and that it secretly sought to influence scientific research to counter the evidence of harm.Syngenta was allegedly aided in suppressing the risks of paraquat by a “reputation management” firm called v-Fluence, the Guardian reported in September.Thousands of US paraquat users who suffer from Parkinson’s are currently suing Syngenta, alleging the company should have warned them of the risk of developing the incurable brain disease, but instead worked to hide the evidence of risk.This story is co-published with the New Lede, a journalism project of the Environmental Working Group More

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      A Personalized Brain Pacemaker for Parkinson’s

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      When Shawn Connolly was diagnosed with Parkinson’s disease nine years ago, he was a 39-year-old daredevil on a skateboard, flipping and leaping from walls, benches and dumpsters through the streets of San Francisco. He appeared in videos and magazines, and had sponsorships from skateboard makers and shops.But gradually, he began to notice that “things weren’t really working right” with his body. He found that his right hand was cupping, and he began cradling his arm to hold it in place. His balance and alignment started to seem off.Over time, he developed a common Parkinson’s pattern, fluctuating between periods of rapid involuntary movements like “I’ve got ants in my pants” and periods of calcified slowness when, he said, “I could barely move.”A couple of years ago, Mr. Connolly volunteered for an experiment that summoned his daring and determination in a different way. He became a participant in a study exploring an innovative approach to deep brain stimulation.In the study, which was published Monday in the journal Nature Medicine, researchers transformed deep brain stimulation — an established treatment for Parkinson’s — into a personalized therapy that tailored the amount of electrical stimulation to each patient’s individual symptoms.The researchers found that for Mr. Connolly and the three other participants, the individualized approach, called adaptive deep brain stimulation, cut in half the time they experienced their most bothersome symptom.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe. More

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      Virginia Democrat battling ‘Parkinson’s on steroids’ won’t seek re-election

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      Democratic congresswoman Jennifer Wexton said on Monday that she will finish out her term but not seek re-election for the northern Virginia-based seat that she has held since beating a Republican incumbent in 2018.Wexton, who was diagnosed with Parkinson’s disease earlier this year, said in a statement that her doctor had “modified my diagnosis to supra-nuclear Palsy”. She described it as a “kind of ‘Parkinson’s on steroids’”.The congresswoman, who is 55, added that she was “heartbroken to have to give up something I have loved after so many years of serving my community”. But she said that taking her prognosis for the coming years into consideration had prompted her to decide “not to seek re-election once my term is complete”.Wexton was part of a new influx of Democrats to Congress that helped flip control of the body midway through Donald Trump’s presidency. Before being elected to Virginia’s 10th district, an area that includes the western Washington DC suburbs of Leesburg and Loudoun county through Fauquier county, Wexton was a member of the state’s senate, a judge and a prosecutor.In 2022, she won re-election by more than 6%.Wexton said that she had not been making as much progress as she had hoped with what was then believed to Parkinson’s. Her new diagnosis – progressive supranuclear palsy (PSP) – is caused by damage to nerve cells in areas of the brain that control thinking and body movements.The National Institutes of Health report that most people with PSP develop eye problems as the condition progresses, and they tend to lean backwards as well as extend their necks. People with Parkinson’s tend to bend forward rather than backwards.The Washington Post reported that Weston had told her staff of her condition: “It’s not OK. It’s not OK at all … I’m going to die, which isn’t fair.”skip past newsletter promotionafter newsletter promotionWexton’s statement said she wanted to spend her “valued time” with her family and friends. She said that until her term in office ends she is “confident and committed as ever to keep up the work that got me into this fight in the first place”. More

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      Rep. Jennifer Wexton Announces Rare Neurological Disorder Diagnosis

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      Ms. Wexton, a Democrat who disclosed a Parkinson’s diagnosis in April, will not seek re-election after learning she has progressive supranuclear palsy, for which there is no effective treatment.Representative Jennifer Wexton, Democrat of Virginia, announced on Monday that she would not seek re-election next year after receiving a diagnosis of a rare neurological disorder.Ms. Wexton, 55, who represents a competitive district in the Virginia suburbs west of Washington, D.C., revealed in a statement that she has progressive supranuclear palsy, which she described in a statement as “Parkinson’s on steroids.”“I’m heartbroken to have to give up something I have loved after so many years of serving my community,” she said.Ms. Wexton was elected to represent Virginia’s 10th Congressional District in 2018, defeating a two-term Republican incumbent, Barbara Comstock, by 12 percentage points.In April, Ms. Wexton announced that she had been diagnosed with Parkinson’s disease, saying at the time that it would not stop her from continuing to live her life, or pursuing her political career.“I’m doing well, and I want to bring about as much good from this diagnosis as I can — including here in Congress,” Ms. Wexton wrote on X, the platform formerly known as Twitter.However, she wrote in her statement on Monday that she had noticed that people in her Parkinson’s support group weren’t having the same experience she was, and that she wasn’t making as much progress as she had hoped. She sought out other medical opinions and testing, which she said had led to her new diagnosis.Ms. Wexton said she planned to serve out the remainder of her term.“While my time in Congress will soon come to a close,” Ms. Wexton said, “I’m just as confident and committed as ever to keep up the work that got me into this fight in the first place for my remaining time in office — to help build the future we want for our children.”What is progressive supranuclear palsy?It is not uncommon for people with progressive supranuclear palsy, also known as P.S.P., to be misdiagnosed with Parkinson’s, as Ms. Wexton was. The two disorders share many symptoms, such as difficulty swallowing, and speech and balance issues.P.S.P. is caused by damage to nerve cells in areas of the brain that control thinking and body movement. It affects walking and balance as well as eye movement, and progresses more rapidly than Parkinson’s. There is currently no treatment that effectively stops or slows the disorder’s progression or symptoms, according to the National Institutes of Health.Symptoms typically appear when a person is in their mid-to-late 60s, later than when Parkinson’s symptoms usually start. Most people with P.S.P. develop severe disability within three to five years of the onset of symptoms, and may experience serious complications such as pneumonia, choking or the risk of head injuries from falls. It can also cause changes in behavior, such as forgetfulness and increased irritability.Given the nature of the disorder, Ms. Wexton said she wanted to spend her “valued time” with her friends and loved ones, including her husband and two sons.Her diagnosis has political implications for 2024.When Ms. Wexton won in 2018, she flipped her Northern Virginia district from red to blue, part of an anti-Trump wave that led to Democrats regaining control of the House. She came into Congress along with two other Democratic women who had flipped seats in Virginia, Abigail Spanberger and Elaine Luria.While Ms. Luria lost her race for re-election last year, Ms. Wexton won her third term by six points. But Ms. Wexton’s district, one of the wealthiest in the country, remains competitive, and is likely to be even more so without an incumbent running for the seat.Ms. Wexton’s decision not to run again leaves Republicans, who hold a slim majority in the House, with an opportunity to pick up a seat in the 2024 election, when Democrats will be angling to win back control of the chamber.Annie Karni More

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      Compassionate Release for Those Aging Behind Bars

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      More from our inbox:Living Well, and Pursuing One’s Passion, With Parkinson’sThe ‘Absurd Contradictions’ of the Migrant SystemA Civilized Argument A Debate QuestionCecilia CarlstedtTo the Editor: Re “Inside a Dementia Unit in a Federal Prison” (Opinion guest essay, Aug. 13):Katie Engelhart vividly describes the absurdity and cruelty of incarcerating frail elders with debilitating dementia. It would be a mistake, though, to conclude simply that expanding compassionate release is the answer. Certainly, that’s warranted, but policymakers should be proactive, not just reactive.As a former parole commissioner, I know that dementia is just the tip of the iceberg of the problem of mass aging behind bars.Countless people (not just men) effectively face a slow death penalty behind bars because of extreme sentences or repeated denials of parole release despite these individuals’ complete transformations. Far from being helpless, many are violence interrupters, mentors, scholars and artists, including people previously convicted of causing serious harm. They have changed.Enacting elder parole bills, which do not guarantee release based on age but rather allow older adults to be individually considered for release by a parole board, can help resolve the crisis of aging behind bars, save substantial money, and return people to the community to repair the harm they long ago caused — before they are on death’s doorstep.Carol ShapiroNew YorkTo the Editor:Dementia units in prisons should primarily serve as a conduit to helping achieve compassionate release. As physicians volunteering with the Medical Justice Alliance, we review the medical care of numerous patients with dementia who are undiagnosed and untreated in the prison system. Patients wake up unsure why they are in prison, hoping that President Nixon might pardon them.We must consider the high cost of normalizing the imprisonment of elderly patients with dementia. Financially, developing “dementia-friendly” prison units incurs significant costs; that money could instead be used to improve community resources such as nursing facilities. Ethically, we must grapple with punishing people who do not pose a threat to others and are unable to understand why they are being punished.Compassionate release laws at the state and federal levels should make dementia an explicit criterion for early release. Facilities should also screen older patients for dementia on a regular basis and develop protocols for requesting compassionate release and expediting placement in memory care facilities. The U.S. prison population is aging and change is urgently needed.Caitlin FarrellNicole MusheroWilliam WeberTo the Editor:As a person who has served three federal prison terms for antiwar protests for a total of almost three years, I found myself shaking my head that the Federal Bureau of Prisons maintains Federal Medical Center Devens to hold men with dementia.The essay noted that most of the men in the dementia unit have no memories of their crimes or why they are incarcerated, yet few are deemed eligible for compassionate release. The United States incarcerates nearly two million people in our thousands of jails and prisons. The U.S. prison system is primitive, lacks redemption and only metes out punishment. The term rehabilitation is simply not part of this cruel system.In my time in more than a half dozen federal prisons, I never met a man I would not have to my home as a dinner guest. Our jails and prisons are filled mostly with people convicted of nonviolent crimes. Many — perhaps the majority — of incarcerated people are poor, mentally ill or substance abusers. Most need medical treatment, not incarceration.I agree with F.M.C. Devens’s clinical director, Dr. Patricia Ruze, who thinks it would be “totally appropriate” to release the whole unit on compassionate grounds and relocate the men to community nursing homes.I’d go one step further: Let’s release all nonviolent people from prison with appropriate community support to help them prosper and avoid recidivism, as well as offer programs of human uplift to the remaining prisoners using the money we save by closing the prisons we will no longer need.Patrick O’NeillGarner, N.C.Living Well, and Pursuing One’s Passion, With Parkinson’sThe pianist Nicolas Hodges has continued to perform and record — with alterations and tough decisions — after receiving a Parkinson’s disease diagnosis.Roderick Aichinger for The New York TimesTo the Editor: Re “Pianist Adapts His Life to Parkinson’s” (Arts & Leisure, Aug. 13):Thank you for demonstrating how the pianist Nicolas Hodges is adapting to life with Parkinson’s disease. Mr. Hodges is testament to the fact that it is possible to continue to live well with Parkinson’s, and the article highlights two key ways to manage symptoms: consistently taking medications (dopamine) and reducing commitments or stress. Exercise and physical activity are also critical to managing symptoms.Recent research published by the Parkinson’s Foundation shows that the number of people in the U.S. diagnosed with Parkinson’s annually has increased by 50 percent, from approximately 60,000 to 90,000. This means that every six minutes, someone in the U.S. is diagnosed with the disease and may encounter similar challenges to those faced by Mr. Hodges.Further funding to support research and drug development are needed in order to find a cure, and the Parkinson’s Foundation and other organizations work tirelessly to advance this.In the meantime, we applaud Mr. Hodges for speaking about his experience with the disease and continuing to pursue his passion. Play on, Mr. Hodges.John L. LehrNew YorkThe writer is president and C.E.O. of the Parkinson’s Foundation.The ‘Absurd Contradictions’ of the Migrant SystemTo the Editor: We have millions of square feet of office space no longer being used and tens of thousands of homeless people and displaced immigrants needing shelter. Many employers cannot fill open jobs while the talents and proven determination of immigrants sit untapped in detention.We can strengthen our economy and confirm our commitment to human dignity and decency by correcting these absurd contradictions.It would be far more cost-effective to use the migrant detention system funds to create a system where people can be quickly helped and trained to be productive contributors to society instead of expensive drains on us all.Even if common decency is not a motivation, pure selfish economic need dictates that we end the waste and do the right thing.Michael E. MakoverGreat Neck, N.Y.A Civilized Argument Christopher Smith for The New York TimesTo the Editor: Re “Imagining the Face-Off in Trump’s Jan. 6 Case,” by David French (column, Aug. 12):I started feeling odd as I read Mr. French’s column. It was so quiet! Two measured, rational voices speaking through the ink, each backing up their arguments with researchable references and free of bitter, ad hominem jabs. A few bits of pique and tooth grinding to humanize both the defense and the prosecution, but all for the sake of clarifying a complex position.How civilized! How rare! It’s a shame that the essay was the voice of one man working his careful way through a thicket of legal complexity and not a real-life exchange of ideas in search of a mutually arrived at truth.Leslie BellDavenport, IowaA Debate QuestionTo the Editor: At the Republican debate I would like to see the moderator ask each of the participants if as president they would pardon Donald Trump if he is convicted of federal crimes.Walter RonaghanHarrison, N.Y. More

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      From Kremlin leak to sperm counts: our readers’ favourite stories of 2021

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      From Kremlin leak to sperm counts: our readers’ favourite stories of 2021 Here are 20 articles that may have helped convince people to support the Guardian’s journalismThe Guardian benefited from hundreds of thousands of acts of support from digital readers in 2021 – almost one for every minute of the year. Here we look at the articles from 2021 that had a big hand in convincing readers to support our open, independent journalism.Kremlin papers appear to show Putin’s plot to put Trump in White House – Luke Harding, Julian Borger and Dan SabbaghExclusive leak reveals Moscow’s deliberations on how it might help Donald Trump win 2016 US presidential race‘We are witnessing a crime against humanity’ – Arundhati RoyThe author and activist plumbs the depths of India’s Covid catastrophe and finds much to reproach the prime minister, Narendra Modi, for‘I’m facing a prison sentence’: US Capitol rioters plead with Trump for pardons – Oliver MilmanThe past very quickly catches up with those who ransacked the seat of US democracyClimate crisis: Scientists spot warning signs of Gulf Stream collapse – Damian CarringtonA shutdown of the Atlantic current circulation system would have catastrophic consequences around the worldAn Afghan woman in Kabul: ‘Now I have to burn everything I achieved’ – A Kabul residentAs the Taliban take the Afghan capital, one woman describes being “a victim of a war that men started”.Plummeting sperm counts, shrinking penises: toxic chemicals threaten humanity – Erin BrockovichA warning from the environmental advocate and author about the damage being wrought by toxic chemicalsPandora papers: biggest ever leak of offshore data exposes financial secrets of rich and powerful – Guardian investigations teamMillions of documents reveal deals and assets of more than 100 billionaires, 30 world leaders and 300 public officialsThe Hill We Climb: the poem that stole the inauguration show – Amanda GormanShe spoke, and millions listened, at Joe Biden’s inaugurationRates of Parkinson’s disease are exploding. A common chemical may be to blame – Adrienne MateiIs an epidemic on the horizon? And is an unpronounceable chemical compound to blame?Capitalism is killing the planet – it’s time to stop buying into our own destruction – George MonbiotThe Guardian columnist at his most incandescent‘Take it easy, nothing matters in the end’: William Shatner at 90, on love, loss and Leonard Nimoy – Hadley FreemanThe actor discusses longevity, tragedy, friendship, success and his Star Trek co-star‘Our biggest challenge? Lack of imagination’: the scientists turning the desert green – Steve RoseIn China, scientists have turned vast swathes of arid land into a lush oasis. Now a team of maverick engineers want to do the same to the SinaiOff-road, off-grid: the modern nomads wandering America’s back country – Stevie TrujilloAcross US public lands thousands of people are taking to van lifeThe greatest danger for the US isn’t China. It’s much closer to home – Robert ReichThe columnist and former secretary of labour warns of enemies withinThe rice of the sea: how a tiny grain could change the way humanity eats – Ashifa KassamCelebrated chef discovered something in the seagrass that could transform our understanding of the sea itself – as a vast gardenRevealed: leak uncovers global abuse of cyber-surveillance weapon – Guardian staffThe Guardian teams up with 16 media organisations around the world to investigate hacking software sold by the Israeli surveillance company NSO GroupBeware: Gaia may destroy humans before we destroy the Earth – James LovelockLegendary environmentalist argues that Covid-19 may well have been one attempt by the planet to protect itself, and that next time it may try harder with something even nastierThe Rosenbergs were executed for spying in 1953. Can their sons reveal the truth? – Hadley FreemanEthel and Julius Rosenberg were sent to the electric chair for being Soviet spies, but their sons have spent decades trying to clear their mother’s name. Are they close to a breakthrough?Out of thin air: the mystery of the man who fell from the sky – Sirin KaleWho was the stowaway who fell from the wheel well of a Boeing plane into a south London garden in the summer of 2019?The life and tragic death of John Eyers – a fitness fanatic who refused the vaccine – Sirin KaleThe 42-year-old did triathlons, bodybuilding and mountain climbing and became sceptical of the Covid jab. Then he contracted the virusIf these pieces move you to support our independent journalism into 2022, you can do so here:
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